| Effector Protein ID: 52840390 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | sdhB |
| Locus tag | lpg0135 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 157650..163277 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | SdhB |
| T4CP requirement | T4CP Depedent |
| Target/Effection | SdhB may play minor roles in Legionella replication |
| UniProt ID | Q5ZZ76 |
| KEGG ID | lpn:lpg0135 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 1875 a.a. [Download] |
| >gi|52840390|ref|YP_094189.1| hypothetical protein lpg0135 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MLLLSIEVINMPDHNSSDIPLSQQIDEVRGLLLKALKAQLDDLIAGKLTPQPSGVPFVHFEKDPPQIATL KKVINCLYHAEEAFKSWESIDTSTLLGKAKAAPKLIRALTQIYKSLGLLDEATPEIRSVIADNYHLLEPL FTQAYTIVQESGWLSEFMEMDVTDKASKVIFQGMDLLGPDIDKWHDTHPLVDAFAKISKLVETISKLQEK DMPGKEKEQAVELVRALLDDLDNNPFISKLSISDFEDSKAIKDLLEWFKNIQDDGFDFSKKSIKQYVSWA NHYLPTLITFADQLERQNYLKPGSLSTNLCSQIEHLGKQVNGILSEPNFGITERVVSIESLKGKREQQIH NAQANSVRAIMATEKQQAATADFYRILEAYKGMNLSQVTEPDRILLRQLYPQIQTALAHASLDLENLLTS VLNTTGPEKTPAKPKSWWELAKGGLGYVASYVVNYNVDKILGTRESVDRFLSSQIASEQFKILIAEKARE KLRTGSDKLEETALQYKAEVRVNAIKSTLRKQPLQREAPPSTFVAVKPSKLVNLRGTLTAIQEMQLSTTV NSTRTNVDTLIHRHLPEKYQACFSTLPYQVNEKDPELVKQIKTIENNLFQLEKALKDFEKIDLSYGIMIR LHYFIAIASAASKLKSSVKELSPEGQKALAPLLQQIMTLGSSFSDTNYTTNDLSALQQLKTEGQARPGSP LGTSPEKTKTLPEETIKGNDKKPKEKTTELLDYADKISTARTLLLSKFKSTLSPAIADSLNPQEHGVPFI HLDQDPPQTAAIKKIINSMYHAECALKTWHGIDTSTRLGKIAAAHQGVAALSQVYKSFALFTEDFSDIHN LIRENHDLIAPVIIEANKLVKEYGWASQFSELDVAQKLGSILGQGINTVQPKTDEITQTASLVKLFSEIP RLLNNISSSLDENAEKSVDELRINSKKIEAIGAVFELFFEENAYLMSMFKGFSAISGLIELNKKIQREGN NLQEITIRQYQKWLKEGYPNLMMMLDEIETRHYLTPGLLSAPIALELDQINDKLNEIIETKPDFKLQKIP LSFYMGDKRIERLMTKKTEHCLALLQIEEQKKAVNTFFGILKHYSGQPLSNIKPNELAQLRLAFVKIQSA MANSNLELSNDFVAALNQLETSPSEEINKIKVTVSQLIKLQPAVENNLSEQKKSSELKIAVIDKAIEHVI AKSFELKSDVSKEINIPQLRRTFLETESKKPIVGPGELKPTSVSSLNTVRGNLAYIQELKLSSTVGMIRE QFSALTRDNFSTRMQKYLIKPPGKPLHVINDKDPLMVRQIKEVENSLYHLETALKQFEQMKKSDSFVSQT KALVEIANHAHELKMAVERFSPELKEHYGPVVRTALSFSNKVQSINYNKEDWADLQFILNRAHKELLKRK TPRDHRIEKAFFEAGIREVQIDRTESAGKKAAKLGVKYAHLASPQLEKARAYLSSRYKNAFGQQPKAIRS LTREQLANEEFMDAEISRLKKTLEEKYGFNIATIKVLLALLEQIQRAGAQAAEVAGMVNTLVTYDFPKIK ENAYRDLLTKLSQEEDYLNLKPGTLINPAMAAVNQLFLSAALELDMPFSKKLSILDDTTYVNILVRQTES DLQTLRKKLSEDPSNHEIAFEIEIKNDKLAFLRQQMVLLEDKNPNQTRNVLLDMQFEVSLRNHLVYTTLK APIAQEYEQIAREYYKKNKNRFLYADDCSKELLQGLKEFEKKHLPDHLIVFEAYDRLRLFSAKLPPKNQD VKEYIENINRELQNRDIPIEQRAIKVKSLPNDAVFIEKLSSADKGTHFLRKFIQFITIITASITEAIKTG GSLIYIYRQKQMEQSIKNIEKSISLKEELHTIKNTDGASPRKGEGQEGEIEFTKL |
| - |
| Nucleotide Sequence: 5628 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:c163277-157650 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGCTACTATTAAGCATAGAGGTGATAAATATGCCAGATCATAACTCATCAGATATTCCGTTATCGCAGC AAATAGATGAAGTCAGGGGATTGCTCCTTAAAGCCCTTAAAGCGCAATTGGATGATCTGATAGCTGGAAA ACTCACACCACAACCAAGTGGCGTTCCTTTTGTTCATTTTGAGAAGGATCCACCACAAATTGCAACTCTA AAAAAAGTCATTAATTGTCTTTATCATGCTGAGGAAGCATTTAAAAGCTGGGAAAGCATTGATACCAGTA CGCTATTGGGTAAAGCCAAAGCAGCACCCAAATTAATCCGTGCACTAACCCAGATATACAAATCCCTGGG TTTACTTGATGAGGCTACCCCTGAAATAAGGAGTGTCATAGCCGACAATTATCATTTACTTGAACCGCTG TTTACTCAAGCTTATACCATCGTGCAAGAGTCTGGCTGGCTATCAGAATTCATGGAAATGGATGTGACCG ATAAAGCATCCAAAGTGATCTTCCAAGGGATGGATTTATTGGGTCCCGATATCGATAAATGGCATGATAC GCATCCTCTTGTTGACGCCTTTGCAAAAATATCAAAACTGGTAGAAACCATATCCAAACTACAAGAAAAG GACATGCCAGGAAAAGAGAAAGAACAAGCGGTAGAATTGGTTCGCGCCTTACTTGATGACCTGGACAATA ACCCTTTTATCAGCAAATTAAGTATCAGTGATTTTGAAGACTCAAAAGCCATAAAGGATTTATTAGAATG GTTTAAGAACATACAAGACGATGGTTTTGATTTTAGCAAGAAATCCATTAAGCAATATGTTTCCTGGGCT AATCACTATTTACCCACATTAATCACCTTCGCTGATCAACTGGAACGACAAAACTATTTAAAACCAGGCA GTTTAAGTACCAATTTGTGTTCTCAAATAGAGCATTTAGGCAAGCAAGTGAATGGCATACTATCTGAACC TAATTTTGGTATTACTGAGCGCGTTGTATCCATAGAATCATTGAAGGGGAAAAGAGAGCAACAAATTCAT AATGCTCAGGCCAACAGTGTGCGAGCTATCATGGCTACCGAAAAACAGCAAGCGGCTACTGCTGATTTTT ATCGAATCCTGGAAGCCTATAAGGGCATGAATCTTTCACAAGTTACAGAGCCGGATCGGATATTACTAAG ACAATTATATCCCCAAATACAAACGGCACTGGCTCATGCCAGTTTAGATCTTGAAAATCTGTTAACCTCT GTTTTAAATACTACCGGCCCTGAAAAAACCCCAGCCAAACCCAAATCATGGTGGGAATTAGCCAAAGGTG GTTTAGGTTATGTAGCCAGTTATGTGGTCAATTACAACGTTGATAAAATCCTTGGAACCAGGGAGTCTGT TGATCGTTTTCTGTCAAGCCAAATTGCGTCCGAGCAATTTAAGATCCTGATTGCTGAAAAAGCTCGTGAA AAATTAAGGACAGGATCAGATAAGCTAGAAGAAACCGCACTGCAATATAAAGCTGAAGTTCGTGTCAATG CTATAAAATCAACTCTGAGAAAACAACCCTTGCAGAGGGAGGCTCCTCCATCCACATTTGTTGCAGTGAA ACCTTCGAAATTAGTCAATCTTCGTGGAACACTAACTGCCATTCAGGAAATGCAATTATCGACTACAGTA AACAGCACAAGAACAAATGTCGATACTCTGATTCATCGCCATTTGCCAGAAAAATATCAAGCCTGTTTTT CAACTCTTCCGTATCAAGTCAATGAAAAGGATCCTGAGTTGGTGAAACAAATTAAAACCATTGAAAATAA TTTGTTTCAATTAGAAAAAGCACTTAAAGATTTTGAAAAAATCGATTTGAGCTATGGAATTATGATCCGA TTGCATTATTTTATCGCAATCGCTTCTGCAGCTTCCAAACTAAAATCAAGTGTCAAAGAACTTTCACCAG AGGGTCAAAAAGCACTAGCTCCACTGTTGCAACAAATTATGACTTTAGGGTCATCTTTCTCAGACACCAA TTATACAACTAATGACTTATCCGCCTTGCAACAATTAAAAACAGAAGGCCAAGCCAGGCCCGGAAGTCCA CTCGGAACATCTCCGGAAAAAACAAAAACATTACCTGAAGAAACTATAAAGGGAAATGACAAAAAACCAA AAGAAAAAACGACTGAATTATTGGATTATGCTGATAAAATCAGTACTGCTCGGACATTGTTATTAAGTAA GTTTAAATCCACCTTATCTCCCGCCATAGCCGACAGTTTAAACCCACAGGAACATGGCGTTCCGTTTATT CATCTTGATCAAGACCCGCCTCAAACAGCGGCAATAAAAAAAATCATCAACAGTATGTATCATGCGGAGT GTGCTCTTAAAACCTGGCATGGCATAGATACCAGCACTAGATTAGGTAAGATTGCTGCAGCACATCAAGG CGTAGCAGCATTATCCCAAGTGTACAAATCATTTGCGTTGTTTACTGAGGATTTCTCAGACATTCACAAT TTAATTCGTGAGAATCACGATTTAATAGCACCTGTGATCATCGAAGCAAACAAGCTGGTTAAAGAGTATG GATGGGCAAGTCAATTCAGTGAACTTGACGTCGCCCAAAAACTGGGAAGCATTTTAGGTCAGGGAATTAA TACAGTTCAACCTAAAACGGATGAAATAACCCAAACCGCTTCACTGGTTAAATTATTTTCAGAAATTCCA AGGCTACTGAACAATATTTCAAGTTCATTGGATGAAAACGCTGAGAAATCAGTTGATGAGTTAAGAATCA ACAGCAAAAAAATTGAAGCCATTGGCGCAGTATTTGAATTGTTTTTTGAAGAAAATGCCTACTTAATGAG CATGTTTAAAGGATTCAGCGCTATCTCAGGTCTTATCGAATTAAATAAAAAAATTCAACGCGAAGGAAAC AACCTGCAAGAAATCACTATTCGACAATACCAGAAATGGTTAAAAGAAGGTTATCCCAATTTGATGATGA TGCTTGATGAAATTGAGACACGCCACTACTTAACCCCAGGCCTGTTATCAGCACCTATTGCCCTGGAATT AGACCAAATTAACGACAAGCTTAATGAAATTATTGAAACCAAACCTGATTTTAAATTACAAAAAATTCCT CTTTCATTCTATATGGGAGATAAGCGCATAGAGCGCTTAATGACTAAAAAAACGGAACACTGCCTCGCAT TGCTGCAAATAGAAGAGCAAAAAAAAGCAGTGAACACTTTTTTCGGGATACTTAAACACTATTCAGGCCA ACCGCTGTCAAACATAAAGCCAAATGAGCTCGCTCAATTGCGTCTTGCTTTTGTTAAGATTCAATCCGCA ATGGCGAATAGTAATTTGGAATTAAGCAATGATTTTGTTGCTGCTTTAAATCAACTTGAAACGTCCCCAT CTGAAGAAATAAATAAAATCAAAGTTACAGTCTCTCAATTGATAAAATTGCAACCTGCTGTTGAAAACAA TTTAAGCGAACAGAAAAAATCCAGTGAATTAAAAATTGCAGTCATTGATAAAGCCATAGAGCACGTTATA GCCAAATCTTTCGAGTTAAAATCTGATGTATCAAAAGAAATCAATATACCCCAGCTGCGCAGAACATTTT TAGAAACTGAAAGCAAGAAGCCTATTGTAGGTCCTGGGGAATTAAAACCAACATCGGTCTCATCTCTCAA CACCGTTCGTGGTAATTTGGCTTACATTCAAGAATTAAAATTATCATCCACTGTGGGTATGATACGAGAG CAATTTTCGGCTCTTACCAGAGATAATTTCTCCACTCGAATGCAAAAATATTTAATCAAACCTCCAGGTA AGCCTTTGCATGTGATAAATGACAAAGATCCGCTCATGGTAAGGCAAATTAAAGAAGTCGAAAACAGTTT ATATCACCTGGAAACCGCTTTAAAACAATTCGAGCAAATGAAAAAGAGCGACAGCTTTGTATCGCAAACA AAAGCGTTGGTAGAAATTGCAAACCATGCTCATGAATTAAAAATGGCAGTGGAACGATTTTCACCCGAGT TAAAAGAGCATTATGGCCCAGTAGTTCGTACCGCATTGAGCTTCAGCAATAAAGTTCAATCCATCAATTA CAACAAAGAGGATTGGGCTGATCTTCAGTTTATTCTGAATAGAGCCCATAAAGAATTGTTAAAAAGAAAA ACTCCAAGAGACCATCGTATTGAAAAAGCTTTTTTTGAAGCCGGGATTCGTGAAGTACAAATCGATCGGA CTGAATCAGCAGGAAAAAAAGCCGCAAAACTGGGTGTAAAATACGCGCATCTGGCCTCCCCTCAGTTAGA GAAAGCAAGAGCCTATTTAAGTTCCAGATACAAAAATGCGTTTGGTCAACAACCTAAGGCTATTCGTTCG TTGACTCGAGAACAATTAGCAAATGAAGAATTTATGGACGCTGAAATTAGCAGATTGAAAAAAACATTGG AAGAGAAGTATGGTTTTAATATTGCAACGATCAAAGTTCTTCTTGCTTTATTAGAACAAATTCAACGGGC TGGAGCTCAGGCTGCTGAGGTAGCCGGTATGGTCAATACCTTGGTTACTTATGACTTCCCCAAGATAAAA GAAAATGCGTATAGGGATTTACTGACAAAATTATCTCAGGAAGAAGACTATCTGAATTTAAAACCAGGCA CATTAATTAATCCAGCCATGGCTGCAGTCAACCAATTATTCTTATCTGCAGCCCTGGAATTGGACATGCC TTTTAGTAAAAAATTATCTATTCTGGACGATACCACTTATGTCAATATTCTCGTCAGACAAACCGAAAGC GATCTGCAAACATTAAGGAAAAAGCTATCCGAAGATCCCTCGAATCATGAAATAGCATTTGAAATTGAGA TTAAGAACGATAAACTAGCTTTCCTCAGGCAACAGATGGTGTTGCTTGAAGATAAAAACCCCAATCAAAC CAGAAATGTCTTATTGGACATGCAGTTCGAGGTGTCATTACGTAATCACCTTGTTTATACAACGCTTAAA GCACCCATTGCCCAGGAATATGAACAAATTGCCAGAGAATATTACAAAAAAAACAAAAATCGCTTTCTGT ATGCCGATGACTGTTCAAAAGAGTTGCTGCAAGGATTGAAAGAATTTGAAAAAAAACATTTGCCTGATCA TTTGATAGTTTTTGAAGCCTACGACAGGCTTCGCCTATTCAGTGCAAAACTTCCCCCTAAAAATCAGGAT GTCAAAGAGTATATTGAGAACATCAATAGAGAATTACAAAATAGAGATATCCCTATAGAGCAACGTGCTA TAAAAGTTAAATCATTACCTAATGACGCTGTCTTTATTGAAAAATTAAGTTCAGCAGATAAAGGCACTCA TTTCCTAAGAAAATTCATTCAGTTCATTACAATCATTACAGCAAGCATCACTGAAGCAATAAAAACCGGG GGCAGTTTGATTTATATTTATCGCCAAAAGCAAATGGAACAATCAATAAAGAATATAGAAAAATCGATAA GCCTTAAAGAAGAACTTCATACCATAAAAAATACTGATGGCGCTTCACCCCGCAAGGGAGAAGGGCAAGA AGGTGAAATCGAATTTACCAAATTGTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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| experimental literature |
| in silico analysis literature |