| Effector Protein ID: 52840385 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg0130 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 151762..154230 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | sidP |
| T4CP requirement | T4CP Depedent |
| Target/Effection | PI-3-phosphatase involved in control of PIP-levels on the LCV and evasion of the endosomal pathway. |
| UniProt ID | Q5ZZ81 |
| KEGG ID | lpn:lpg0130 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 822 a.a. [Download] |
| >gi|52840385|ref|YP_094184.1| hypothetical protein lpg0130 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MGKGIILRVLENTILSPQVFDTLERLLPGYKVEYFKEQPDYRKSIARRIDSLHDAFSFILKAYPLDPKHT SLTVATLSTYAAECKASCDLEKLTLEELHLELERFTAKLVEAIAIAWKWPKGKAVKEAIASLNEAEQYVL MSRGRSDIATIMPIEMGSETKYVLQYDESLSPVYEQWLSELKQLKEYNFPKTPAWFKNLPPYQQAYYCNL NLSSVDPKKALQHFNTFFGNWGDIAKRSLNLTTELNQIHTNSPPYPSWFNELSPAQQAMIRVLSATPHEI KSSLKEFKKFMVEQARNDQYASTLSLVPKLPQWYWVLSEKQQYFLEYALKNAEKIEDVVSYLSSRHRTLP APGNYGAHSLYLIDDEGKETLFYDKRYRSSHVASRDSLKFPEDVQQRHVDSNLVKVMEFAKPQQPLLLQT LISPIHAVDYIPTVVTDFLPELPPDLELYKIAREAVTRSKRRHEIFQHNHPFNIAKRYYYTQATDTDSEF LLKAAQKYASSKPGLQALIDDYKAVLESPLGSATFWDYDGRELFLSSLEELIILNMGGYSYGSCVSGKDR KAVELLHTDAMILYKAKYGNWPKFGIPKEKQERVNFINIVVDLYISRHQHELAGQNAPGSEGIKTPDWYW PNDIAEAINERLGTEKALAYDDRLATDNEVKNISKDLRSFFLPENELHCLLIAKQLGEKMCTMLYDVLSA LINEERRFQKSSKDSWKLRWFSDKDVSSTPTGILNIREVMHDENSGNDNVLRIGKIFAAVLNRPESDSSR TTATNSVYDRIRKLLQPLSSETTLQTLAEEAILEWSSLFESSKRENSGLVYV |
| - |
| Nucleotide Sequence: 2469 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:151762-154230 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGGGAAAAGGTATAATTTTACGTGTTTTGGAAAATACAATATTATCTCCTCAGGTATTTGATACACTAG AGCGACTTCTACCTGGTTACAAAGTAGAGTATTTCAAAGAGCAGCCAGATTATCGTAAAAGCATCGCTCG CCGGATAGACAGCCTTCATGATGCCTTTTCATTTATCTTAAAAGCTTACCCCCTCGATCCAAAACATACT TCTCTGACGGTTGCAACCTTAAGTACTTATGCCGCAGAATGCAAGGCTTCATGTGACCTGGAAAAACTGA CATTAGAAGAGTTGCATCTTGAGCTCGAACGATTTACGGCCAAATTGGTTGAAGCTATTGCAATCGCGTG GAAATGGCCTAAAGGTAAGGCAGTCAAAGAGGCGATAGCCAGCCTTAATGAAGCAGAGCAGTATGTCTTA ATGAGTCGGGGTCGTAGCGATATCGCTACCATAATGCCTATTGAAATGGGCAGTGAGACAAAGTATGTTT TGCAATATGATGAATCCCTTTCTCCCGTTTATGAACAATGGCTAAGTGAATTAAAACAATTAAAAGAATA TAATTTTCCTAAAACACCTGCCTGGTTTAAAAATCTGCCGCCCTATCAACAAGCTTATTATTGTAATCTG AATTTAAGTTCTGTTGATCCTAAAAAAGCGCTGCAGCACTTTAATACATTTTTTGGCAATTGGGGAGATA TTGCAAAAAGGTCACTGAATTTGACCACGGAATTAAATCAAATACATACCAACTCACCGCCTTATCCTTC CTGGTTCAATGAATTAAGCCCTGCTCAGCAAGCCATGATTCGCGTCTTGTCTGCTACTCCACATGAGATT AAATCCAGCTTAAAAGAGTTTAAAAAATTTATGGTTGAGCAGGCCAGGAATGATCAATACGCATCGACTT TGAGCCTAGTGCCTAAGCTTCCACAGTGGTATTGGGTTTTGTCCGAGAAACAACAATACTTTTTGGAATA TGCTCTCAAAAATGCAGAAAAGATTGAGGATGTCGTATCTTATTTATCAAGCCGGCACCGAACTTTGCCT GCTCCAGGCAATTATGGTGCGCACAGTTTATATTTAATCGATGATGAGGGTAAAGAAACTTTATTTTATG ACAAGAGGTATCGTTCAAGCCATGTTGCCAGCCGTGATTCGTTAAAATTTCCTGAGGATGTCCAGCAGCG TCATGTTGACTCTAATCTGGTTAAGGTGATGGAATTTGCCAAACCTCAGCAGCCTTTGTTATTGCAAACA TTAATTAGCCCTATCCATGCAGTAGATTATATTCCAACGGTGGTTACAGACTTTTTACCGGAATTACCTC CTGATCTGGAGTTGTATAAAATTGCCCGAGAAGCGGTTACCCGGAGCAAACGCAGGCATGAAATATTCCA GCATAATCATCCTTTTAATATTGCCAAGCGTTATTATTATACTCAGGCAACGGATACAGACAGCGAGTTT TTATTAAAAGCAGCGCAGAAATATGCGTCTTCCAAGCCTGGATTGCAGGCGCTAATCGATGATTATAAGG CCGTTTTAGAGTCGCCTTTAGGCTCTGCAACATTTTGGGATTACGATGGCAGGGAATTATTTCTTAGCTC TTTGGAAGAACTGATTATTCTCAACATGGGCGGCTATAGCTATGGCTCCTGTGTCAGTGGTAAAGACAGA AAAGCAGTAGAGTTATTGCATACTGATGCGATGATTTTGTATAAAGCAAAATATGGAAATTGGCCTAAAT TTGGAATTCCCAAAGAAAAACAAGAACGAGTCAATTTCATCAATATTGTTGTAGATCTTTATATCTCCAG ACATCAACATGAGCTTGCAGGGCAAAATGCGCCAGGTTCAGAGGGAATCAAAACGCCTGATTGGTACTGG CCAAACGATATCGCTGAGGCCATTAACGAGCGCTTGGGCACTGAGAAAGCATTAGCCTATGATGACCGAT TAGCCACTGATAATGAAGTGAAGAATATTAGCAAGGATTTGCGTTCCTTTTTTCTACCAGAAAACGAATT GCATTGCTTGTTAATTGCCAAACAGCTAGGCGAAAAAATGTGTACAATGCTTTATGATGTACTAAGCGCT TTAATCAATGAGGAGCGCAGATTTCAAAAATCAAGCAAAGATTCCTGGAAATTACGTTGGTTCTCTGATA AAGATGTGAGCTCAACACCTACTGGAATACTCAATATTCGTGAAGTAATGCATGATGAAAACTCGGGCAA TGATAATGTTCTTCGGATTGGAAAAATATTTGCAGCTGTTTTAAATCGGCCAGAAAGCGACTCATCAAGA ACTACAGCAACCAATTCAGTCTATGATCGTATTAGGAAATTATTACAGCCCCTGTCATCAGAAACCACAT TACAAACATTGGCAGAAGAAGCCATTTTAGAATGGTCTTCTTTGTTTGAGAGTTCCAAAAGAGAAAACAG TGGCTTGGTTTATGTGTAA |
| Reference |
(1) Toulabi L et al. (2013). Identification and structural characterization of a Legionella phosphoinositide phosphatase. J Biol Chem. 288(34):24518-27. [PudMed:23843460] 
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(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| experimental literature |
| in silico analysis literature |