| Effector Protein ID: 33598790 |
 T4SS name [ID] | Ptl [387] |
| Gene symbol | ptxD |
| Locus tag | BPP4306 |
| Strain | Bordetella parapertussis 12822 |
| Replicon | chromosome [GenBank: NC_002928] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 4638793..4639251 [+] |
| Product | toxin subunit 4 |
| Effector type | Protein |
| Descripton | PtxD |
| T4CP requirement | T4CP Indepedent |
| Target/Effection | A subunit of pertussis toxin (PT). PT is involved in the colonization of the respiratory tract and the establishment of infection of Bordetella pertussis causing whooping cough |
| UniProt ID | P0A3R6 |
| KEGG ID | bpa:BPP4306 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Pertus-S4-tox [PF09275], Evalue: 7.3e-77, Aligned region: 43..152 |
| Protein Sequence: 152 a.a. [Download] |
| >gi|33598790|ref|NP_886433.1| ptxD gene product [Bordetella parapertussis 12822] MLRRFPTRTTAPGQGGARRSRVRALAWLLASGAMTHLSPALADVPYVLVKTNMVVTSVAMKPYEVTPTRM LVCGIAAKLGAAASSPDAHVPFCFGKDLKRPGSSPMEVMLRAVFMQQRPLRMFLGPKQLTFEGKPALELI RMVECSGKQDCP |
| - |
| Nucleotide Sequence: 459 bp [Download] |
| >gi|33594723|ref|NC_002928.3|:4638793-4639251 Bordetella parapertussis 12822 chromosome, complete genome ATGCTGAGACGCTTCCCCACTCGAACCACCGCCCCGGGACAGGGCGGCGCCCGGCGGTCGCGCGTGCGCG CCCTGGCGTGGTTGCTGGCATCCGGCGCGATGACGCATCTTTCCCCCGCCCTGGCCGACGTTCCTTATGT GCTGGTGAAGACCAATATGGTGGTCACCAGCGTAGCCATGAAGCCGTATGAAGTCACCCCGACGCGCATG CTGGTCTGCGGCATCGCCGCCAAGCTGGGCGCCGCGGCCAGCAGCCCGGACGCGCACGTGCCGTTCTGCT TCGGCAAGGATCTCAAGCGTCCCGGCAGCAGTCCCATGGAAGTCATGTTGCGCGCCGTCTTCATGCAACA ACGGCCGCTGCGCATGTTCCTGGGTCCCAAGCAACTCACTTTCGAAGGCAAGCCCGCGCTCGAACTGATC CGGATGGTCGAATGCAGCGGCAAGCAGGATTGCCCCTGA |
| Reference |
| (1) Parkhill J; Sebaihia M; Preston A; Murphy LD; Thomson N; Harris DE; Holden MT; Churcher CM; Bentley SD; Mungall KL; Cerdeno-Tarraga AM; Temple L; James K; Harris B; Quail MA; Achtman M; Atkin R; Baker S; Basham D; Bason N; Cherevach I; Chillingworth T; Collins M; Cronin A; Davis P; Doggett J; Feltwell T; Goble A; Hamlin N; Hauser H; Holroyd S; Jagels K; Leather S; Moule S; Norberczak H; O'Neil S; Ormond D; Price C; Rabbinowitsch E; Rutter S; Sanders M; Saunders D; Seeger K; Sharp S; Simmonds M; Skelton J; Squares R; Squares S; Stevens K; Unwin L; Whitehead S; Barrell BG; Maskell DJ (2003). Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. Nat Genet. 35(1):32-40. [PudMed:12910271] |