| Effector Protein ID: 33598789 |
 T4SS name [ID] | Ptl [387] |
| Gene symbol | ptxA |
| Locus tag | BPP4304 |
| Strain | Bordetella parapertussis 12822 |
| Replicon | chromosome [GenBank: NC_002928] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 4637270..4638079 [+] |
| Product | toxin subunit 1 |
| Effector type | Protein |
| Descripton | PtxA |
| T4CP requirement | T4CP Indepedent |
| Target/Effection | A subunit of pertussis toxin (PT). PT is involved in the colonization of the respiratory tract and the establishment of infection of Bordetella pertussis causing whooping cough |
| UniProt ID | Q7W2U8 |
| KEGG ID | bpa:BPP4304 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Pertussis_S1 [PF02917], Evalue: 3.6e-127, Aligned region: 36..268 |
| Protein Sequence: 269 a.a. [Download] |
| >gi|33598789|ref|NP_886432.1| ptxA gene product [Bordetella parapertussis 12822] MRCTRAIRQTARTGWLTWLAILAVTAPMTSPAWADDPPATVYRYDSRPPEDVFQNGFTAWGNNDNVLEHL TGRSCQVGSSNSAFVSTSSSRRYTEVYLEHRMQEAVEAERAGRGTGHFIGYIYEIRADNNFYGAASSYFE YVDTYGDNAGRILAGALATYQSEYLAHRRIPPENIRTVTRVYHNGITGETTTTEYPNLRYVSQQTRANTN PYTSRRSTASIVGTLVRMAPVTGACMARQAESPEAMAAWSERTGEAMVLVYYESIAYSF |
| - |
| Nucleotide Sequence: 810 bp [Download] |
| >gi|33594723|ref|NC_002928.3|:4637270-4638079 Bordetella parapertussis 12822 chromosome, complete genome ATGCGTTGCACTCGGGCAATTCGCCAAACCGCAAGAACAGGCTGGCTGACGTGGCTGGCGATTCTTGCCG TCACGGCGCCCATGACTTCGCCGGCATGGGCCGACGATCCGCCCGCCACGGTATACCGCTATGACTCCCG CCCGCCGGAGGACGTTTTCCAGAACGGATTCACGGCGTGGGGAAACAACGACAATGTGCTTGAACACCTG ACCGGACGTTCCTGCCAGGTCGGCAGCAGCAACAGCGCTTTCGTCTCCACCAGCAGCAGCCGGCGCTATA CCGAGGTCTATCTCGAACATCGCATGCAGGAAGCGGTCGAGGCCGAACGCGCCGGCAGGGGCACCGGCCA CTTCATCGGCTACATCTACGAAATCCGCGCCGACAACAATTTCTACGGCGCCGCCAGCTCGTACTTCGAA TACGTCGACACTTATGGCGACAATGCCGGCCGTATCCTCGCCGGCGCGCTGGCCACCTACCAGAGCGAAT ATCTGGCGCACCGGCGCATTCCGCCCGAGAACATCCGCACGGTAACGCGCGTCTATCACAACGGCATCAC CGGCGAGACCACGACCACGGAATATCCGAACCTTCGCTACGTCAGCCAGCAGACTCGCGCCAATACCAAC CCCTATACATCGCGAAGGTCCACCGCGTCGATCGTCGGCACATTGGTGCGCATGGCGCCGGTGACGGGCG CTTGCATGGCGCGGCAGGCCGAAAGCCCCGAGGCCATGGCAGCCTGGTCCGAGCGCACCGGCGAGGCGAT GGTTCTCGTGTACTACGAAAGCATCGCGTATTCGTTCTAG |
| Reference |
| (1) Parkhill J; Sebaihia M; Preston A; Murphy LD; Thomson N; Harris DE; Holden MT; Churcher CM; Bentley SD; Mungall KL; Cerdeno-Tarraga AM; Temple L; James K; Harris B; Quail MA; Achtman M; Atkin R; Baker S; Basham D; Bason N; Cherevach I; Chillingworth T; Collins M; Cronin A; Davis P; Doggett J; Feltwell T; Goble A; Hamlin N; Hauser H; Holroyd S; Jagels K; Leather S; Moule S; Norberczak H; O'Neil S; Ormond D; Price C; Rabbinowitsch E; Rutter S; Sanders M; Saunders D; Seeger K; Sharp S; Simmonds M; Skelton J; Squares R; Squares S; Stevens K; Unwin L; Whitehead S; Barrell BG; Maskell DJ (2003). Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. Nat Genet. 35(1):32-40. [PudMed:12910271] |