| Effector Protein ID: 33594642 |
 T4SS name [ID] | Ptl [386] |
| Gene symbol | ptxC |
| Locus tag | BP3787 |
| Strain | Bordetella pertussis Tohama I |
| Replicon | chromosome [GenBank: NC_002929] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 3990696..3991379 [+] |
| Product | toxin subunit 3 |
| Effector type | Protein |
| Descripton | PtxC |
| T4CP requirement | T4CP Indepedent |
| Target/Effection | A subunit of pertussis toxin (PT). PT is involved in the colonization of the respiratory tract and the establishment of infection of Bordetella pertussis causing whooping cough |
| UniProt ID | P04979 |
| KEGG ID | bpe:BP3787 |
| PDB ID | 1PTO, 1BCP, 1PRT |
| Domain hit(s) vs Pfam | Pertussis_S2S3 [PF02918], Evalue: 6.8e-62, Aligned region: 118..226 APT [PF03440], Evalue: 5.1e-37, Aligned region: 31..117 |
| Protein Sequence: 227 a.a. [Download] |
| >gi|33594642|ref|NP_882286.1| toxin subunit 3 [Bordetella pertussis Tohama I] MLINNKKLLHHILPILVLALLGMRTAQAVAPGIVIPPKALFTQQGGAYGRCPNGTRALTVAELRGNAELQ TYLRQITPGWSIYGLYDGTYLGQAYGGIIKDAPPGAGFIYRETFCITTIYKTGQPAADHYYSKVTATRLL ASTNSRLCAVFVRDGQSVIGACASPYEGRYRDMYDALRRLLYMIYMSGLAVRVHVSKEEQYYDYEDATFQ TYALTGISLCNPAASIC |
| - |
| Nucleotide Sequence: 684 bp [Download] |
| >gi|33591275|ref|NC_002929.2|:3990696-3991379 Bordetella pertussis Tohama I chromosome, complete genome ATGCTGATCAACAACAAGAAGCTGCTTCATCACATTCTGCCCATCCTGGTGCTCGCCCTGCTGGGCATGC GCACGGCCCAGGCCGTTGCGCCAGGCATCGTCATCCCGCCGAAGGCACTGTTCACCCAACAGGGCGGCGC CTATGGACGCTGCCCGAACGGAACCCGCGCCTTGACCGTGGCCGAACTGCGCGGCAACGCCGAATTGCAG ACGTATTTGCGCCAGATAACGCCCGGCTGGTCCATATACGGTCTCTATGACGGTACGTACCTGGGCCAGG CGTACGGCGGCATCATCAAGGACGCGCCGCCAGGCGCGGGGTTCATTTATCGCGAAACTTTCTGCATCAC GACCATATACAAGACCGGGCAACCGGCTGCGGATCACTACTACAGCAAGGTCACGGCCACGCGCCTGCTC GCCAGCACCAACAGCAGGCTGTGCGCGGTATTCGTCAGGGACGGGCAATCGGTCATCGGAGCCTGCGCCA GCCCGTATGAAGGCAGGTACAGAGACATGTACGACGCGCTGCGGCGCCTGCTGTACATGATCTATATGTC CGGCCTTGCCGTACGCGTCCACGTCAGCAAGGAAGAGCAGTATTACGACTACGAGGACGCCACATTCCAG ACCTATGCCCTCACCGGCATTTCCCTCTGCAACCCGGCAGCGTCGATATGCTGA |
| Reference |
(1) Rambow-Larsen AA; Weiss AA (2004). Temporal expression of pertussis toxin and Ptl secretion proteins by Bordetella pertussis. J Bacteriol. 186(1):43-50. [PudMed:14679223] 
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| experimental literature |