| Effector Protein ID: 33594641 |
 T4SS name [ID] | Ptl [386] |
| Gene symbol | ptxE |
| Locus tag | BP3786 |
| Strain | Bordetella pertussis Tohama I |
| Replicon | chromosome [GenBank: NC_002929] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 3990212..3990613 [+] |
| Product | toxin subunit 5 |
| Effector type | Protein |
| Descripton | PtxE |
| T4CP requirement | T4CP Indepedent |
| Target/Effection | A subunit of pertussis toxin (PT). PT is involved in the colonization of the respiratory tract and the establishment of infection of Bordetella pertussis causing whooping cough |
| UniProt ID | P04981 |
| KEGG ID | bpe:BP3786 |
| PDB ID | 1PTO, 1BCP, 1PRT |
| Domain hit(s) vs Pfam | Pertus-S5-tox [PF09276], Evalue: 8.8e-66, Aligned region: 37..133 |
| Protein Sequence: 133 a.a. [Download] |
| >gi|33594641|ref|NP_882285.1| toxin subunit 5 [Bordetella pertussis Tohama I] MQRQAGLPLKANPMHTIASILLSVLGIYSPADVAGLPTHLYKNFTVQELALKLKGKNQEFCLTAFMSGRS LVRACLSDAGHEHDTWFDTMLGFAISAYALKSRIALTVEDSPYPGTPGDLLELQICPLNGYCE |
| - |
| Nucleotide Sequence: 402 bp [Download] |
| >gi|33591275|ref|NC_002929.2|:3990212-3990613 Bordetella pertussis Tohama I chromosome, complete genome ATGCAGCGGCAAGCAGGATTGCCCCTGAAGGCGAACCCCATGCATACCATCGCATCCATCCTGTTGTCCG TGCTCGGCATATACAGCCCGGCTGACGTCGCCGGCTTGCCGACCCATCTGTACAAGAACTTCACTGTCCA GGAGCTGGCCTTGAAACTGAAGGGCAAGAATCAGGAGTTCTGCCTGACCGCCTTCATGTCGGGCAGAAGC CTGGTCCGGGCGTGCCTGTCCGACGCGGGACACGAGCACGACACGTGGTTCGACACCATGCTTGGCTTTG CCATATCCGCGTATGCGCTCAAGAGCCGGATCGCGCTGACGGTGGAAGACTCGCCGTATCCGGGCACTCC CGGCGATCTGCTCGAACTGCAGATCTGCCCGCTCAACGGATATTGCGAATGA |
| Reference |
(1) Rambow-Larsen AA; Weiss AA (2004). Temporal expression of pertussis toxin and Ptl secretion proteins by Bordetella pertussis. J Bacteriol. 186(1):43-50. [PudMed:14679223] 
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| experimental literature |