| Effector Protein ID: 29655148 |
 T4SS name [ID] | Dot/Icm [157] |
| Gene symbol | - |
| Locus tag | CBU_1863 |
| Strain | Coxiella burnetii RSA 493 |
| Replicon | chromosome [GenBank: NC_002971] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1791765..1793576 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | CvpE（Coxiella vacuolar protein E） |
| T4CP requirement | T4CP Depedent |
| Target/Effection | CvpB, CvpC, CvpD and CvpE confer effector functions associated with PV bio genesis. They are C. burnetii effectors that target components of the late endosomal system, and that CvpC also targets recycling endosomes. |
| UniProt ID | Q83AM0 |
| KEGG ID | cbu:CBU_1863 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 603 a.a. [Download] |
| >gi|29655148|ref|NP_820840.1| hypothetical protein CBU_1863 [Coxiella burnetii RSA 493] MRNDDDTHSTLTSSSEQVSESKIVPKDSQKPSDPNVHQNGTDVTDSAKQNASLKEVTVVTLPPDLKALEG DTHPTPMPSSREVLFNPNVHKNGTPLTHSVDPNGLSKDDEVTIVALESESKALEKELKKKGINYFKIGKT IANVAYTASLCLVFYKLSAPRGVADGVISALVNAPSAAIFFDQFFGKVLINYNPKRVTKTHFALSLTGLA AGNIAAIAGEQIAEDAVKGSSAWIFYGGLGVSLIYTFTSRTLGLPGAVGYLLNPLLGRCRPFPELEQFRK DLEKNYLNPAVQRINEKTPERFIEVFYDTIKENPNKWTGYDIYKNTIEKAFQVGGLIAVQHFFGLFQQLA AEGWGKISPQLENNCGLNSISAATTAFFYYLLVLKLPPTFRKSLEQIWILGVHNSRTLPAKIIKTALLLA TLGGAGVAAYFSGSGMAEETARYDQLAQNGTLPFCVNNPPLSPWEGIDGNVNELWMTIVAGVGCNFTGML FLFNPILDFFIKKSHENPWCIQSMLAVLESAPILNSNQLEKELGSWIPLIQGKRPTAIQAIENKRSLVKI AENTNLPRPKFWFCGDLWKCSSNDENTRLLSETEDPVPSALTA |
| - |
| Nucleotide Sequence: 1812 bp [Download] |
| >gi|77358712|ref|NC_002971.3|:c1793370-1791559 Coxiella burnetii RSA 493 chromosome, complete genome ATGCGAAATGATGATGATACTCATTCAACGTTGACCTCGTCTTCTGAACAAGTTTCTGAGAGTAAAATTG TTCCCAAAGATTCACAAAAACCTTCCGATCCAAACGTACACCAAAATGGCACAGACGTGACTGATTCTGC TAAGCAAAATGCCTCTTTGAAGGAGGTTACCGTTGTCACACTGCCGCCGGATTTAAAGGCGCTTGAAGGT GATACTCATCCAACGCCGATGCCGTCTTCTAGAGAAGTTCTTTTTAATCCAAACGTTCATAAAAATGGCA CTCCTTTGACTCATTCTGTCGATCCAAATGGCCTTTCGAAGGATGATGAAGTTACCATTGTCGCACTGGA GTCGGAGTCAAAGGCGCTTGAAAAAGAATTGAAAAAAAAGGGTATTAATTATTTTAAAATTGGAAAAACA ATCGCGAATGTAGCCTATACCGCCTCACTTTGTTTAGTTTTTTATAAATTAAGCGCTCCCCGGGGGGTGG CTGATGGCGTTATTTCCGCTCTTGTCAATGCGCCTTCTGCGGCTATATTTTTCGATCAATTCTTTGGTAA AGTACTCATTAATTATAATCCTAAACGTGTCACCAAGACTCATTTTGCTTTGTCTTTAACCGGCTTGGCG GCTGGAAATATTGCCGCTATTGCAGGAGAACAAATTGCAGAAGATGCTGTAAAAGGTTCTTCGGCATGGA TCTTTTATGGTGGATTAGGGGTATCTCTTATCTATACCTTTACAAGCCGTACGCTTGGTTTGCCTGGAGC AGTAGGATATTTACTTAATCCTCTCTTAGGGCGATGTAGACCCTTTCCAGAGCTAGAGCAATTTCGCAAA GATTTGGAAAAAAATTATTTAAATCCTGCGGTGCAAAGGATTAATGAGAAAACCCCAGAACGATTTATTG AGGTTTTTTATGATACGATAAAAGAAAATCCCAACAAATGGACAGGTTACGATATTTATAAAAACACCAT CGAAAAAGCGTTTCAAGTTGGGGGCCTCATCGCCGTGCAACATTTTTTTGGTCTTTTTCAACAGCTGGCG GCAGAAGGTTGGGGAAAAATCTCCCCCCAACTCGAAAATAATTGTGGGCTAAATTCTATTTCCGCCGCGA CCACCGCTTTTTTTTATTATCTTTTGGTCTTGAAACTTCCACCCACCTTTCGCAAGTCCTTGGAACAAAT CTGGATCTTGGGAGTACATAATTCGAGAACGCTGCCAGCGAAAATAATAAAGACCGCACTCTTGTTGGCC ACCCTCGGTGGCGCTGGAGTTGCTGCTTATTTTTCTGGGTCGGGCATGGCGGAGGAAACAGCGCGTTATG ACCAACTTGCCCAGAACGGGACGTTGCCATTTTGCGTTAATAACCCCCCTCTAAGTCCTTGGGAGGGAAT AGATGGTAACGTGAACGAACTGTGGATGACAATCGTCGCGGGCGTAGGGTGTAATTTCACGGGTATGCTT TTCTTGTTTAATCCAATTCTGGATTTTTTTATTAAGAAAAGTCATGAGAATCCATGGTGTATTCAAAGTA TGTTAGCTGTGTTGGAAAGCGCTCCAATATTAAATTCAAATCAACTTGAGAAAGAATTGGGTAGTTGGAT CCCTCTGATACAAGGAAAGAGACCCACTGCGATTCAAGCGATTGAGAATAAGCGTTCTCTAGTTAAAATC GCTGAAAATACCAATCTTCCAAGACCAAAATTCTGGTTCTGTGGAGATTTATGGAAGTGTTCCTCTAACG ATGAGAATACTCGATTGCTATCGGAAACAGAAGATCCTGTACCTTCTGCACTTACTGCGTAA |
| Reference |
(1) Larson CL et al. (2015). Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication. Infect Immun. 83(2):661-70. [PudMed:25422265]  
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| experimental literature |
| in silico analysis literature |