| Effector Protein ID: 29655105 |
 T4SS name [ID] | Dot/Icm [157] |
| Gene symbol | - |
| Locus tag | CBU_1818 |
| Strain | Coxiella burnetii RSA 493 |
| Replicon | chromosome [GenBank: NC_002971] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1749016..1750461 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | CvpD（Coxiella vacuolar protein D） |
| T4CP requirement | T4CP Depedent |
| Target/Effection | CvpB, CvpC, CvpD and CvpE confer effector functions associated with PV bio genesis. They are C. burnetii effectors that target components of the late endosomal system, and that CvpC also targets recycling endosomes. |
| UniProt ID | Q83AR2 |
| KEGG ID | cbu:CBU_1818 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 481 a.a. [Download] |
| >gi|29655105|ref|NP_820797.1| hypothetical protein CBU_1818 [Coxiella burnetii RSA 493] MSRLPSKTKYHSSHRSLNRKTPLLQRSSETNSLRESGIETASSQLSLAASSYTPIDEEMTELELKIYLFL FTRALNHKLGYTQENNPDDKAQKAGIDINLDCLNYLLEILYQNLEPQLEKGANLSYHKSSTARKALEYHE TLNSRLKKKIAKDAEHKNPLTLLRILNTKTTSISTLIGTGGGIGITGAGAIAGSAAAGIGTAVTVGVLLF YLCWRTTSEYWKKKNAEKLFEHTDQIDNENIIELVSALSAFYIVKEFEHKNMQKASLKLSLNPESLFEIF QNIYHNKSFRLPSQLPIQKELKAIAKQAKIDADKIHTHLIEYVNTNKAQSISINLYALIIPSFAYNSEES PTVVKTVAALHAWLWALDKTLDMKDFLFRNSFEKRLEKVRAGVVKTMKTFKEEVNNVLLETDDSSSGVSL LADEDKTDRVKEWVNKQKLPSPGALSPIKSASHLALFSSLREQKDKAVNSSGSRLSLRLGN |
| - |
| Nucleotide Sequence: 1446 bp [Download] |
| >gi|77358712|ref|NC_002971.3|:1748815-1750260 Coxiella burnetii RSA 493 chromosome, complete genome ATGTCTAGATTGCCATCCAAAACTAAATATCATTCTTCTCATCGCAGCCTAAATAGAAAAACCCCATTAC TTCAGAGAAGTTCTGAAACTAATAGTCTTCGTGAAAGTGGAATAGAAACGGCATCTAGTCAATTATCCCT AGCCGCATCAAGTTATACACCTATTGACGAAGAAATGACTGAATTAGAATTAAAAATATATTTATTTCTT TTTACTAGAGCGCTCAATCATAAACTTGGCTACACTCAAGAGAACAACCCCGACGATAAAGCACAAAAGG CTGGAATTGACATTAATTTAGATTGTTTGAACTATTTACTGGAAATTTTATACCAAAACTTAGAACCTCA ATTAGAAAAAGGCGCTAATTTGAGCTACCACAAATCTTCAACAGCTCGTAAAGCCCTTGAATATCATGAG ACGCTTAATAGTAGGCTAAAAAAGAAAATCGCCAAAGATGCCGAACATAAAAACCCGCTCACTCTCCTTC GGATTTTGAATACAAAAACAACCTCTATTTCAACTTTAATCGGCACGGGCGGAGGAATTGGAATAACCGG AGCTGGGGCCATAGCGGGAAGCGCTGCGGCGGGTATTGGGACAGCCGTAACGGTTGGCGTATTACTTTTT TATTTATGCTGGCGAACAACTTCGGAATATTGGAAGAAAAAAAATGCTGAAAAACTCTTTGAACATACAG ATCAAATCGATAATGAAAACATAATAGAGTTAGTTTCAGCCCTGTCTGCGTTTTATATTGTAAAAGAATT TGAACATAAAAATATGCAAAAAGCCTCCCTAAAACTAAGTCTGAACCCTGAATCTCTTTTTGAGATATTC CAAAATATATACCATAATAAATCATTTCGTTTGCCGTCCCAACTACCCATTCAAAAAGAATTAAAAGCAA TTGCCAAACAAGCTAAAATAGATGCTGATAAAATTCATACGCATCTAATAGAATATGTTAACACTAATAA AGCTCAATCTATTTCTATAAATCTCTATGCACTAATCATTCCTAGTTTTGCATATAATTCTGAAGAATCT CCAACTGTTGTAAAGACAGTAGCTGCTTTACATGCCTGGCTGTGGGCATTAGATAAAACGCTAGATATGA AGGATTTCCTTTTTAGAAATTCTTTTGAAAAGCGATTAGAAAAAGTAAGGGCAGGAGTAGTAAAAACAAT GAAAACCTTTAAAGAGGAAGTGAATAACGTTTTGTTAGAAACTGACGATAGTTCATCCGGGGTATCGCTT TTGGCAGATGAAGATAAAACGGATAGAGTCAAGGAGTGGGTTAACAAGCAAAAACTCCCATCCCCTGGTG CGTTAAGCCCTATCAAAAGCGCCTCCCACCTTGCATTATTCTCTTCTCTTCGAGAGCAGAAAGACAAGGC AGTTAATTCAAGTGGTTCTCGACTCTCGTTGCGTCTGGGAAACTAG |
| Reference |
(1) Larson CL et al. (2015). Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication. Infect Immun. 83(2):661-70. [PudMed:25422265]  
|
| experimental literature |
| in silico analysis literature |