| Effector Protein ID: 29655057 |
 T4SS name [ID] | Dot/Icm [157] |
| Gene symbol | - |
| Locus tag | CBU_1769 |
| Strain | Coxiella burnetii RSA 493 |
| Replicon | chromosome [GenBank: NC_002971] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1700146..1700763 [-] |
| Product | alpha/beta hydrolase |
| Effector type | Protein |
| Descripton | coxH3 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q83AV9 |
| KEGG ID | cbu:CBU_1769 |
| PDB ID | 3TRD |
| Domain hit(s) vs Pfam | Abhydrolase_5 [PF12695], Evalue: 5.5e-25, Aligned region: 39..188 Abhydrolase_6 [PF12697], Evalue: 3e-18, Aligned region: 39..136 Abhydrolase_6 [PF12697], Evalue: 3e-18, Aligned region: 144..190 Abhydrolase_1 [PF00561], Evalue: 1e-10, Aligned region: 63..134 Peptidase_S15 [PF02129], Evalue: 1.6e-09, Aligned region: 15..124 DLH [PF01738], Evalue: 4.7e-08, Aligned region: 85..190 |
| Protein Sequence: 205 a.a. [Download] |
| >gi|29655057|ref|NP_820749.1| alpha/beta hydrolase [Coxiella burnetii RSA 493] MTNEDFLIQGPVGQLEVMITRPKGIEKSVTGIICHPHPLHGGTMNNKVVTTLAKALDELGLKTVRFNFRG VGKSQGRYDNGVGEVEDLKAVLRWVEHHWSQDDIWLAGFSFGAYISAKVAYDQKVAQLISVAPPVFYEGF ASLTQMASPWLIVQGDQDEVVPFEQVKAFVNQISSPVEFVVMSGASHFFHGRLIELRELLVRNLA |
| - |
| Nucleotide Sequence: 618 bp [Download] |
| >gi|77358712|ref|NC_002971.3|:c1700763-1700146 Coxiella burnetii RSA 493 chromosome, complete genome ATGACGAATGAAGATTTTTTAATCCAAGGCCCGGTTGGGCAGTTAGAAGTAATGATTACTCGTCCCAAAG GAATTGAAAAGTCGGTGACGGGGATTATTTGTCATCCACACCCCTTGCATGGTGGGACGATGAATAACAA GGTGGTTACCACCTTAGCTAAGGCCTTGGACGAATTGGGATTGAAAACCGTGCGTTTTAATTTTCGTGGC GTGGGTAAGAGTCAGGGGCGATACGATAATGGGGTAGGCGAGGTCGAGGATTTAAAAGCGGTTCTTCGAT GGGTCGAGCACCACTGGTCTCAGGATGACATTTGGCTTGCTGGTTTTTCTTTTGGCGCTTATATCTCAGC GAAGGTGGCATACGATCAAAAAGTAGCGCAGTTGATTAGCGTTGCTCCTCCTGTTTTTTACGAAGGCTTC GCTTCGTTGACTCAAATGGCTTCCCCGTGGCTAATTGTTCAGGGTGACCAGGATGAAGTAGTGCCATTTG AGCAGGTAAAAGCATTTGTTAACCAAATTTCCTCTCCGGTAGAGTTTGTAGTTATGTCCGGCGCAAGCCA TTTTTTTCATGGGCGTTTGATTGAGTTAAGGGAATTATTGGTCCGAAATTTAGCATAG |
| Reference |
| (1) McDonough JA; Newton HJ; Roy CR (2012). Coxiella burnetii Secretion Systems. Adv Exp Med Biol. 984:171-97. [PudMed:22711632] |
(2) Chen C; Banga S; Mertens K; Weber MM; Gorbaslieva I; Tan Y; Luo ZQ; Samuel JE (2010). Large-scale identification and translocation of type IV secretion substrates by Coxiella burnetii. Proc Natl Acad Sci U S A. 107(50):21755-60. [PudMed:21098666] 
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| experimental literature |