| Effector Protein ID: 29654516 |
 T4SS name [ID] | Dot/Icm [157] |
| Gene symbol | - |
| Locus tag | CBU_1213 |
| Strain | Coxiella burnetii RSA 493 |
| Replicon | chromosome [GenBank: NC_002971] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1157067..1159040 [+] |
| Product | ankyrin repeat-containing protein |
| Effector type | Protein |
| Descripton | AnkI |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q83CB4 |
| KEGG ID | cbu:CBU_1213 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Ank_2 [PF12796], Evalue: 6e-19, Aligned region: 362..428 Ank_2 [PF12796], Evalue: 6e-19, Aligned region: 372..453 Ank_2 [PF12796], Evalue: 6e-19, Aligned region: 440..508 Ank_4 [PF13637], Evalue: 2.7e-11, Aligned region: 369..426 Ank_4 [PF13637], Evalue: 2.7e-11, Aligned region: 408..450 Ank_5 [PF13857], Evalue: 6.8e-09, Aligned region: 400..449 |
| Protein Sequence: 657 a.a. [Download] |
| >gi|29654516|ref|NP_820208.1| ankyrin repeat-containing protein [Coxiella burnetii RSA 493] MRESSENQKKVFYSYLRDEFGLKPYIQLPVHYIAYCGQMKDVIRVLQMAKNRLKPETFQSLLKDTRHTDK VTGTVYAHFYYNAVRNINIWKVDNIIKVLNLFKYEDDNTLQNKENVILAYIYLTLSRNDVSLLEECINKF KTAFPITTIHALKFGCFDDKMRLSAYALQKGASLAIAYFKFTPLALAEYLNTRASRKDAIETWVSLMREG LLLLDNLTAILKDLKGEILKIIPQVINLIYPLIDSPEEKEEKQPEKHTTLKDYCNVLISTYNDLDRSTFL GNSDTSNEQKFQLIAAQFLYSEDKDSKCLNEVTDNLSLKKRIHQPLNSSGLLLLNELIRKNKHRTVYSLV SPDSAVRVANPDEKDVTKRSALHWAVEKSDDSVEWLKTIQLLLHQMTTQADPDKEGKTAVHIAARTQKPK TLKLLLQHFRCRESILIKNNKGETPLHIAAVTKTDDSGTIIRLLAEQPDTQCNLEERNWNGNTAFLVACT ENNTSAVFELMSLGCDQDTCGRHGQRVYKNLINSNHSSYNEAFVNKLEELRNNSASRNSKFTSFAPSAPS FPLNQPRQNHEEREEGLTLEQKGETKEEQNHGHEADEMAKRLALFKCKVTRLLQIRQAQTCTVIVGGESI SGVHSPPSRKSLGVLLIPFGSVPPLKQ |
| - |
| Nucleotide Sequence: 1974 bp [Download] |
| >gi|77358712|ref|NC_002971.3|:1157067-1159040 Coxiella burnetii RSA 493 chromosome, complete genome ATGAGAGAATCATCAGAAAATCAAAAAAAGGTATTTTATAGTTACCTAAGGGATGAGTTTGGCCTGAAGC CCTACATCCAACTTCCAGTACATTACATTGCTTATTGTGGTCAGATGAAGGACGTGATACGAGTATTGCA AATGGCTAAAAACAGGCTCAAGCCAGAAACATTTCAGTCATTACTCAAAGACACGCGCCACACGGATAAA GTTACCGGAACGGTTTATGCACACTTTTACTATAATGCAGTTCGTAATATTAATATCTGGAAAGTTGACA ATATCATCAAAGTGTTAAATCTATTTAAATACGAAGATGACAACACATTGCAAAATAAAGAAAACGTAAT TCTAGCTTATATCTATTTGACCCTCTCTCGAAATGATGTATCTTTATTAGAAGAATGTATTAACAAGTTT AAGACCGCTTTCCCTATAACCACTATTCACGCACTGAAGTTCGGCTGCTTTGATGATAAGATGAGGTTAT CTGCCTATGCCCTCCAAAAGGGGGCATCATTGGCAATTGCTTATTTTAAATTTACGCCTTTGGCTTTAGC AGAATATCTTAATACGCGGGCTTCTCGTAAAGACGCCATCGAAACATGGGTTTCCCTCATGAGAGAAGGA TTACTACTTTTGGATAATTTGACTGCTATTTTGAAGGATCTAAAGGGAGAAATTTTAAAAATTATCCCTC AAGTGATTAATCTCATCTATCCACTCATTGATTCGCCAGAAGAAAAAGAGGAAAAACAACCAGAGAAGCA CACAACGCTGAAAGATTATTGCAATGTTCTTATATCAACATATAACGATCTTGACCGTTCAACTTTCCTA GGGAATTCTGACACATCAAATGAGCAAAAATTTCAGCTCATTGCGGCTCAGTTTCTATATTCAGAAGATA AAGACTCAAAATGTCTTAACGAGGTTACTGATAACCTTAGCTTGAAAAAAAGAATACATCAGCCCCTGAA TTCCAGCGGTTTATTGTTATTGAATGAATTGATTAGGAAAAATAAACATCGCACCGTTTATAGTTTGGTA TCCCCAGATTCCGCTGTGCGGGTTGCTAATCCCGATGAAAAGGATGTCACTAAACGATCCGCTTTACATT GGGCAGTTGAAAAAAGCGACGACAGCGTGGAATGGCTTAAAACGATTCAGCTATTACTTCATCAAATGAC AACACAGGCCGATCCCGATAAAGAAGGTAAAACAGCCGTGCATATCGCCGCGCGCACTCAAAAACCAAAA ACGCTAAAGTTATTACTTCAGCATTTTCGTTGTCGAGAATCAATTTTGATAAAAAACAATAAAGGTGAGA CCCCCTTACACATTGCAGCCGTCACGAAAACGGATGATAGTGGTACCATTATTCGCTTATTAGCAGAACA ACCCGATACCCAATGTAATCTAGAAGAACGAAATTGGAACGGTAATACCGCATTCTTGGTAGCGTGTACG GAAAACAATACAAGCGCCGTTTTTGAATTAATGAGCTTGGGATGCGATCAGGATACTTGTGGTCGTCATG GACAGCGTGTCTATAAAAATCTGATAAATTCCAATCACTCCTCTTATAACGAAGCCTTTGTAAATAAACT TGAAGAGTTACGTAACAATTCCGCTTCAAGGAATAGTAAGTTCACTTCCTTTGCGCCATCGGCGCCTTCG TTCCCGCTCAACCAGCCCAGGCAAAATCATGAAGAAAGAGAAGAAGGTCTTACCTTAGAGCAAAAGGGTG AAACGAAAGAAGAACAAAATCATGGCCACGAAGCCGACGAGATGGCTAAGCGGTTGGCTTTATTTAAATG TAAAGTCACCCGCCTACTGCAAATTCGGCAAGCGCAAACTTGTACTGTTATTGTGGGTGGCGAATCAATA TCAGGAGTTCATAGCCCGCCTTCAAGAAAGAGCTTGGGGGTATTATTGATACCATTTGGGAGTGTACCTC CATTGAAGCAATAA |
| Reference |
| (1) McDonough JA; Newton HJ; Roy CR (2012). Coxiella burnetii Secretion Systems. Adv Exp Med Biol. 984:171-97. [PudMed:22711632] |
(2) Voth DE; Howe D; Beare PA; Vogel JP; Unsworth N; Samuel JE; Heinzen RA (2009). The Coxiella burnetii ankyrin repeat domain-containing protein family is heterogeneous, with C-terminal truncations that influence Dot/Icm-mediated secretion. J Bacteriol. 191(13):4232-42. [PudMed:19411324] 
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(3) Zusman T; Aloni G; Halperin E; Kotzer H; Degtyar E; Feldman M; Segal G (2007). The response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii. Mol Microbiol. 63(5):1508-23. [PudMed:17302824]
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| experimental literature |