| Effector Protein ID: 29654003 |
 T4SS name [ID] | Dot/Icm [157] |
| Gene symbol | - |
| Locus tag | CBU_0665 |
| Strain | Coxiella burnetii RSA 493 |
| Replicon | chromosome [GenBank: NC_002971] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 607020..608006 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | CvpA（Coxiella vacuolar protein A） |
| T4CP requirement | T4CP Depedent |
| Target/Effection | CvpA modulates clathrin-medi ated vesicle transport events on the PV membrane that promote vacuole biogenesis. |
| UniProt ID | Q83DN3 |
| KEGG ID | cbu:CBU_0665 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 328 a.a. [Download] |
| >gi|29654003|ref|NP_819695.1| hypothetical protein CBU_0665 [Coxiella burnetii RSA 493] MLLRGIIVSRESKEESKLLSEEQTETKVFHSFISHLLGDADSVSRPKEFASFWETYRVLNYKDLFEEYHP HNRNEQNRIKENALDILLDAANQPTAYLRRNNYIKTRMINAGIPAEAIEKKNTERVRLGIKKSICLEGIR LNGDILETPNYGFVTPLTYPEHLALMRELYSEQLPCIRHINLLFMNFRYGWRGYSSKQHIVELCEIIEST KQLQSLDLANCQIRADNLKMVLQTIIGDSQRSQSLQKLVLDCNYLSKDLLNFIKNDLLPQCQNLSELSLN YVMEDVFTEDSKFIESGTDSETCEHLIAEIQQLLSMGARDQMGLTRLQ |
| - |
| Nucleotide Sequence: 987 bp [Download] |
| >gi|77358712|ref|NC_002971.3|:607018-608004 Coxiella burnetii RSA 493 chromosome, complete genome ATGCTTTTAAGAGGAATAATAGTGTCACGCGAATCAAAAGAAGAATCTAAATTATTATCAGAAGAACAAA CTGAAACGAAAGTATTTCATTCCTTTATTTCCCATTTGTTAGGGGATGCCGATAGTGTTAGTAGGCCCAA AGAATTTGCATCGTTTTGGGAGACTTATAGGGTCTTAAATTACAAAGATCTATTTGAAGAATATCATCCC CACAATCGGAATGAGCAAAACAGAATAAAAGAGAATGCTCTTGATATCCTTCTCGATGCAGCCAATCAGC CAACGGCATACCTTCGTCGAAATAATTATATTAAAACCCGCATGATTAATGCGGGTATACCTGCCGAGGC TATAGAGAAAAAAAATACTGAACGGGTAAGGTTAGGGATAAAGAAATCTATTTGTCTAGAGGGAATAAGA TTGAATGGAGATATCCTTGAGACACCAAATTATGGTTTTGTGACTCCTCTAACTTATCCGGAACATCTTG CACTGATGCGAGAATTATATTCCGAACAACTTCCCTGTATTCGTCATATAAATTTACTTTTCATGAATTT TCGCTATGGATGGAGAGGTTACTCAAGCAAACAACATATCGTGGAGTTGTGTGAGATTATTGAATCAACC AAGCAATTACAATCGCTGGATTTAGCCAACTGTCAGATACGTGCAGATAATTTAAAAATGGTATTGCAAA CTATTATTGGCGACTCACAAAGAAGTCAATCGCTTCAAAAGCTAGTATTGGATTGTAATTATCTTAGCAA AGACTTATTAAATTTTATAAAAAATGACCTATTACCCCAATGTCAAAATTTAAGCGAATTGAGTTTAAAT TATGTAATGGAGGATGTTTTTACTGAGGATTCAAAATTTATCGAAAGTGGCACAGATTCTGAGACTTGTG AACACTTGATAGCTGAAATACAGCAATTATTATCAATGGGGGCAAGAGATCAAATGGGTTTAACCAGACT TCAATAG |
| Reference |
(1) Larson CL et al. (2013). Coxiella burnetii effector protein subverts clathrin-mediated vesicular trafficking for pathogen vacuole biogenesis. Proc Natl Acad Sci U S A. 110(49):E4770-9. [PudMed:24248335] 
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| experimental literature |