SecReT4
Effector Protein ID: 296108435
T4SS name [ID]Dot/Icm [43]
Gene symbol-
Locus taglpa_04063
StrainLegionella pneumophila 2300/99 Alcoy
Repliconchromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon]
Location [Strand]3256362..3259808 [+]
Productinteraptin
Effector typeProtein
DescriptonLepA
T4CP requirementT4CP Depedent
Target/EffectionBacterial egress
UniProt IDD5TAJ9
KEGG IDlpa:lpa_04063
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 1148 a.a.     [Download]
>gi|296108435|ref|YP_003620136.1| interaptin [Legionella pneumophila 2300/99 Alcoy]
MNEIILHLMNEISALTPPINPLNLKQIFSSTLLPEGKAPVEVESQLNLLLLIKKYVDEYSSLAEEQEEYK
RKKHKLDEVMKKGEELQRKISDLAKKIEHAKNELNPLYKEIEPKANEVLSKQNPLAPPYKFPEYGEVQKS
IVVGHYSYLFKTSKEIETTRAKLKLVLLKNKWNALMTDLSQLGIQPPVEEDAVDSLQKFIAAVELEIKKL
TRACEKWDELQKRFAKQLSATDINKKETELEKQIELLLKDLGRIETAVTNHSLAPDLKAELIRKFQESED
PQGLIQEYQNQIDGLLSNFNPSSWLSWYSDSNYSDNQQKLKNSVSFLQLLAQQKELKIKHHELVKQQELL
IEAIPEIPSNEEDISIYKKLVPDAIDLINEIPIESIPNFVLPSGLSYDSSPADFYLVLLILMPKISEKKE
QFSQALEKLQEMPALGKQIQQLRSGYDLPITMDVQLPSLHEAEENKDSLNEEDPLKEELKSQIKLCQSYL
ETAKQIDLLMKDHGQTTNEAKALIEQLRLISNQPLKNEDINSIKEDLSTLANQIQSLVSELNQLPLPNLN
DEKIDPPLEKQEIAVDKAIPLTVELMNPAQVIQIGNDSHIEKQQLDNEEETPVVLESLRPRPVIHKESES
ITQKLQVDNGHEMPVVLDSTCPPQVIHKELESTTEKLQVGNGHEIPLVLESTRSPQIIHPEPESVGKKQH
VEVEQEIPVALELIRPSSMVEKDSVATVEKQQATERQETPIVLESTRPSPMVQKDTGLSGEKQHKEIEQE
IPVIPELTPRTQVVRQDSESSLEQQVPNGQETLAFVKSSPSEPLRPSSPEIPVISRKPNGLSLFNGHDEL
SEDNILDFFDEASISSEEDSETLAIDKGKVNSLGIDKAFKEKPVSTGHELDKLSNPQHQESAPSISPLLP
PSSILLKQKLDSFHVQNMEYIKHHSEEIQLWYKGLYDAVQSSCVNETLGLKALHLLKDILFELKNQNDLS
ALLAYKRMCPNPLQDIQNILRLKPALPILDESIDEEQQLKNWPEELQKFHQQYVKLKKEYPLEAELFIQA
IHSLISIKHLMELPDAKTSNREAMPLITQDPRYEPLKRHRGFTKAWEYIEDFFRMLIGKLTGQDEYEYSK
RPCFFKTRSHRLLEEADTMLHSMAPTSS
-
Nucleotide Sequence: 3447 bp     [Download]
>gi|296105497|ref|NC_014125.1|:3256362-3259808 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome
ATGAACGAAATCATACTGCACTTAATGAATGAAATCTCTGCCTTGACTCCACCAATTAACCCCTTAAATT
TAAAGCAAATATTTAGTTCAACCCTACTGCCGGAAGGAAAAGCTCCTGTTGAAGTTGAATCCCAATTAAA
TCTTTTATTGTTAATTAAAAAATATGTTGATGAATATTCCAGTTTAGCTGAAGAACAAGAAGAGTATAAA
AGGAAAAAACACAAACTAGATGAGGTCATGAAAAAAGGAGAAGAACTGCAAAGAAAAATTTCTGATTTGG
CTAAAAAAATTGAACACGCAAAAAATGAATTAAATCCTTTATACAAAGAAATCGAACCTAAAGCGAACGA
AGTCCTGTCCAAACAAAATCCATTAGCGCCTCCTTATAAATTCCCTGAATACGGAGAGGTTCAAAAATCA
ATTGTAGTCGGGCACTACAGTTATCTCTTCAAAACCAGTAAGGAAATAGAAACTACACGTGCCAAATTAA
AGTTGGTTTTGCTCAAAAATAAATGGAATGCCTTAATGACAGATTTGTCTCAGTTGGGCATTCAACCCCC
TGTGGAAGAAGATGCTGTTGATAGTTTACAAAAATTTATAGCTGCAGTTGAATTGGAAATTAAAAAATTA
ACTCGCGCTTGCGAAAAATGGGATGAATTGCAAAAGCGATTCGCCAAACAATTATCTGCAACTGATATTA
ACAAAAAAGAGACTGAGCTAGAAAAACAAATTGAACTATTGCTTAAAGACCTGGGTCGTATTGAAACCGC
AGTGACTAACCACTCCCTGGCACCCGATTTAAAAGCAGAGTTAATCAGGAAATTTCAGGAAAGTGAAGAC
CCTCAAGGATTGATACAGGAATACCAAAATCAGATTGATGGATTATTATCTAATTTTAACCCATCTTCCT
GGCTTTCATGGTATTCGGATTCTAATTATTCTGATAATCAGCAAAAACTTAAGAATTCAGTTAGCTTCCT
GCAATTATTAGCTCAACAAAAAGAGCTAAAAATCAAACATCATGAACTTGTGAAACAGCAAGAACTGTTG
ATTGAAGCGATACCAGAAATTCCTTCAAATGAAGAGGATATATCTATTTATAAAAAATTAGTTCCTGATG
CCATTGACCTGATAAATGAAATACCAATAGAAAGTATACCAAATTTTGTTTTACCAAGTGGCCTTTCTTA
TGACTCTTCACCGGCCGATTTTTATTTGGTACTTCTCATTCTCATGCCAAAAATTTCGGAAAAGAAGGAA
CAATTTTCACAAGCGTTGGAAAAACTTCAAGAAATGCCTGCTCTGGGCAAACAAATACAACAACTAAGAA
GTGGATACGATTTACCTATAACTATGGATGTACAACTTCCAAGTTTGCATGAAGCTGAAGAAAATAAAGA
TTCATTGAATGAAGAGGATCCTCTTAAAGAAGAGTTAAAAAGCCAGATTAAACTATGCCAATCTTATCTT
GAAACAGCCAAGCAAATTGATTTGCTTATGAAAGATCATGGACAAACAACCAATGAAGCAAAAGCACTTA
TTGAGCAATTGCGTTTAATTTCAAATCAACCGCTAAAGAACGAAGACATAAACTCTATTAAAGAAGATTT
ATCTACTCTTGCCAATCAAATCCAATCCCTTGTGTCTGAATTAAATCAATTACCTTTGCCTAATCTGAAC
GATGAAAAAATTGATCCTCCATTGGAAAAACAGGAAATAGCAGTAGATAAAGCAATCCCTCTTACTGTGG
AATTGATGAACCCTGCCCAAGTAATTCAGATAGGCAATGATTCTCACATAGAAAAACAGCAGCTAGACAA
TGAGGAAGAAACGCCGGTTGTTCTGGAATCATTACGCCCCCGCCCAGTCATTCATAAGGAGTCTGAATCT
ATCACCCAAAAACTGCAAGTAGACAATGGACACGAAATGCCAGTTGTTCTGGATTCAACATGCCCTCCTC
AAGTCATTCATAAGGAACTTGAATCTACCACTGAAAAACTGCAAGTAGGCAATGGACACGAAATACCGCT
TGTTCTCGAGTCAACACGCTCTCCTCAAATCATTCATCCTGAGCCTGAATCTGTTGGTAAAAAACAGCAT
GTAGAAGTAGAGCAAGAGATACCAGTCGCACTGGAATTAATACGACCCTCTTCTATGGTTGAAAAGGATT
CCGTGGCTACTGTAGAAAAACAGCAAGCAACTGAGAGACAAGAAACACCAATCGTCCTTGAATCAACACG
ACCCTCTCCTATGGTTCAGAAAGACACTGGGCTTTCTGGTGAAAAACAGCATAAAGAGATAGAACAAGAA
ATACCTGTCATTCCGGAATTAACGCCCCGCACCCAAGTGGTTCGGCAAGACTCTGAGTCCAGTTTAGAAC
AACAAGTACCCAACGGGCAAGAAACACTGGCTTTTGTCAAATCAAGCCCATCGGAACCATTGAGACCATC
AAGCCCCGAGATTCCAGTTATATCCAGGAAACCAAATGGCTTGTCATTATTCAATGGTCACGATGAATTA
TCAGAAGATAATATTTTAGACTTTTTTGATGAGGCTAGTATCTCATCTGAAGAAGATTCTGAGACACTTG
CCATAGACAAAGGAAAAGTAAATTCCTTAGGTATTGATAAAGCATTTAAAGAAAAACCGGTTTCTACAGG
CCATGAGTTAGATAAATTATCAAATCCTCAACACCAGGAATCCGCTCCTAGCATCTCCCCTTTACTACCA
CCATCTTCTATCCTGCTTAAGCAAAAATTAGATTCATTTCATGTACAAAACATGGAATATATAAAGCATC
ATTCAGAAGAAATACAGCTATGGTATAAAGGTTTATATGATGCAGTGCAAAGTTCTTGTGTAAATGAGAC
TTTGGGTCTTAAAGCACTTCATCTTTTAAAAGACATCTTGTTTGAATTAAAAAATCAAAATGATTTATCT
GCATTACTGGCTTACAAGCGCATGTGCCCAAACCCATTGCAAGATATACAAAATATTCTCCGCTTAAAAC
CTGCTCTGCCTATACTTGATGAATCGATTGATGAAGAACAGCAGTTAAAGAATTGGCCTGAAGAATTGCA
AAAATTTCATCAGCAATATGTAAAATTGAAAAAGGAATATCCATTGGAAGCTGAATTATTTATTCAGGCA
ATCCATTCACTTATTTCAATTAAACATTTGATGGAACTCCCTGATGCAAAAACTTCAAACCGAGAAGCCA
TGCCTCTCATTACTCAAGATCCTCGATATGAGCCTTTAAAACGGCATAGAGGATTTACAAAAGCATGGGA
ATATATTGAAGATTTTTTCCGAATGTTAATAGGTAAGTTAACAGGGCAAGATGAATATGAGTATTCAAAA
AGACCTTGTTTTTTCAAAACAAGATCTCACCGATTACTTGAAGAGGCTGATACAATGCTCCACTCCATGG
CTCCAACAAGTAGTTAA

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature