Effector Protein ID: 296108202 |
T4SS name [ID] | Dot/Icm [43] |
Gene symbol | sPS1 |
Locus tag | lpa_03745 |
Strain | Legionella pneumophila 2300/99 Alcoy |
Replicon | chromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 3000890..3002278 [+] |
Product | Serine/threonine protein kinase |
Effector type | Protein |
Descripton | LegK3 |
T4CP requirement | T4CP Depedent |
Target/Effection | Unknown |
UniProt ID | D5T950 |
KEGG ID | lpa:lpa_03745 |
PDB ID | NA |
Domain hit(s) vs Pfam | Pkinase [PF00069], Evalue: 3.2e-25, Aligned region: 50..311 Pkinase_Tyr [PF07714], Evalue: 9.3e-12, Aligned region: 50..309 |
Protein Sequence: 462 a.a. [Download] |
>gi|296108202|ref|YP_003619903.1| Serine/threonine protein kinase [Legionella pneumophila 2300/99 Alcoy] MFDRNIKEIINELQEKDLLPDTGKIIGGPRNQFDKKGEMKQGYLFSVINKEPIGKGGFASVYPVTLYRQG ETGFVKKSTDHKKFVTKKFNLNKLKIKYTNLNIENLIEKEFEFCRKAGHLSIKPPVYNNNKCYLTMKRMP GIDLNRIFNKLMANPHYLTEGQRIKITYALLLALKNQVIDKGIIHRDIKPENIHVKVVDPVEVNIFDYGL AKNAGEDDNLFPGSESWAAPEMFTGLKHDSKADIFSMGRVIAFLWGESATNYLSNNPLNKSRNAAKNLNL PAQVKWVEPFLKQMLAERQEDRIEIDSAINQFKQLASINAPKLKLPQSSIKNHSNINNLCFFQNPTKSTN NSDLIQLNIQRNIKKDLQELLENLPSEFSHYRSNIIFKNTIGRFTTIQKMMNELNQIMDENESQDIPMEL YDFIHQYQNKFLHASEANIIRKINGFLEDIEYQNLTNSGFEL |
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Nucleotide Sequence: 1389 bp [Download] |
>gi|296105497|ref|NC_014125.1|:3000890-3002278 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome ATGTTTGATAGAAATATAAAAGAAATAATCAATGAATTACAAGAAAAGGATTTACTTCCGGACACTGGAA AAATTATCGGCGGACCCCGAAATCAATTTGATAAGAAAGGAGAGATGAAACAAGGGTATCTTTTTTCAGT TATTAACAAAGAACCAATAGGAAAAGGTGGGTTCGCTTCTGTTTATCCTGTTACGCTGTATCGGCAAGGT GAAACTGGATTTGTTAAAAAATCTACTGATCATAAGAAGTTTGTAACAAAGAAATTTAATTTAAATAAAC TTAAAATAAAATACACCAACTTAAATATAGAAAATTTAATTGAAAAAGAGTTTGAGTTTTGTCGAAAAGC AGGGCACTTAAGTATAAAACCACCTGTTTACAATAATAATAAATGTTATCTGACGATGAAACGAATGCCA GGGATAGATTTAAATCGTATCTTCAATAAATTAATGGCTAATCCTCATTATCTTACAGAGGGTCAGCGAA TTAAGATAACCTATGCTTTATTATTGGCTTTGAAAAATCAGGTGATTGATAAAGGAATTATTCATCGAGA TATAAAGCCTGAGAATATTCATGTTAAAGTGGTTGACCCTGTTGAAGTGAATATTTTCGATTACGGACTT GCCAAAAATGCAGGCGAAGACGATAACCTATTTCCTGGAAGTGAAAGTTGGGCAGCGCCTGAAATGTTTA CTGGCTTAAAGCACGATAGTAAAGCTGATATTTTTTCAATGGGAAGAGTTATTGCCTTCTTATGGGGCGA AAGTGCTACAAACTATTTGAGCAATAACCCCCTTAATAAAAGCCGAAATGCAGCAAAAAACCTTAATTTG CCCGCACAAGTTAAATGGGTAGAGCCATTTTTGAAACAAATGTTAGCGGAAAGACAAGAGGATAGAATAG AGATTGATTCCGCAATAAACCAATTTAAGCAACTTGCGTCCATTAACGCGCCGAAGCTTAAATTACCTCA ATCCTCAATAAAGAATCACTCAAATATTAATAATCTCTGCTTTTTTCAAAATCCAACTAAAAGCACAAAC AATTCTGATCTTATACAATTAAATATTCAGCGGAATATCAAAAAGGATTTGCAGGAATTATTAGAGAATC TTCCTAGTGAATTTTCTCATTATCGCAGTAATATAATTTTTAAAAACACAATAGGCCGTTTTACAACAAT ACAAAAAATGATGAATGAACTAAATCAGATCATGGATGAAAACGAATCTCAAGATATACCCATGGAATTA TATGATTTTATTCATCAATATCAGAATAAATTTTTGCATGCAAGCGAAGCTAATATTATAAGAAAAATAA ATGGCTTCTTAGAAGATATAGAGTATCAAAATTTAACCAATTCAGGCTTTGAATTATAA |
Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] |
in silico analysis literature |