SecReT4
Effector Protein ID: 296108165
T4SS name [ID]Dot/Icm [43]
Gene symbol-
Locus taglpa_03688
StrainLegionella pneumophila 2300/99 Alcoy
Repliconchromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon]
Location [Strand]2965740..2967362 [-]
Producthypothetical protein
Effector typeProtein
DescriptonLnaB
T4CP requirementT4CP Depedent
Target/EffectionLnaB is a activator of NF-kappaB (Losick, et al. 2010)
UniProt IDD5T913
KEGG IDlpa:lpa_03688
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 540 a.a.     [Download]
>gi|296108165|ref|YP_003619866.1| hypothetical protein lpa_03688 [Legionella pneumophila 2300/99 Alcoy]
MSYQKIELSISLSLDSPKLDESDFILLSVKYLEKSLGKKKEFSGFFEDIEKLYFNQNYKEAIEKILDFCK
KNESLLSEQVVQRLAEVAPRLKSNPKDNESRRLYETLYADHLESAIKQESDLSVFNELRDSYNAVKPEYA
VTHETEIKTLDEAKQFILSFVMLNDNVELPLKAQSERYPKKDRSREELGNTPSANPGIMKPNSPNFTDNL
VPVRDVPKIAINEKVVGGYSKTKPTTPFVASLSGTTYSLMVVLTDYIEKHKTDKDIEKKVNQIINLWISS
YIKEGYHSYSEVVDVLTEPFLQSIFDKANIKLNYGVLDDTHAEFRKAQDYVFGLTIRAAMHHELQERFKN
KEKLQEEVKNFESGLNKLNQDVESTGRHREALNKLNEVFQDWSAGKKSYDAFKSESNQLIRDIESEEQKS
NRGLGSMLKNFGNYLLYLITLRFLKEDYLKPSSPVSMLVTELRGTLEQIDNFHKNSLSLKKATQPDPKNT
SPSVETSDVLKSAVDNDKLNKNQDSEVKKTLDSEQMEEVQRQDDKSARLQ
-
Nucleotide Sequence: 1623 bp     [Download]
>gi|296105497|ref|NC_014125.1|:c2967362-2965740 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome
ATGTCATACCAAAAAATAGAACTCAGTATTTCATTATCATTAGATTCTCCAAAATTAGATGAGTCTGATT
TTATATTGCTCTCAGTTAAGTATCTTGAAAAGTCACTTGGCAAAAAGAAAGAGTTTTCTGGTTTTTTTGA
AGACATAGAAAAGCTCTATTTTAACCAGAATTACAAGGAAGCAATTGAAAAAATATTGGATTTTTGTAAA
AAAAATGAATCCTTGTTAAGTGAGCAAGTTGTCCAGAGGCTGGCAGAGGTCGCTCCCAGATTAAAAAGCA
ATCCTAAAGACAATGAAAGCAGAAGGCTTTATGAAACCTTGTATGCAGATCACCTTGAATCAGCCATTAA
ACAAGAGAGTGATCTTTCCGTATTTAACGAATTGAGAGACAGTTATAATGCGGTGAAACCTGAGTATGCA
GTAACTCATGAGACCGAAATCAAAACTTTGGATGAAGCAAAGCAATTTATTTTATCTTTTGTCATGCTGA
ATGATAATGTTGAATTACCTTTAAAAGCGCAATCAGAGAGATACCCCAAAAAGGACAGATCCAGAGAGGA
ATTGGGGAATACTCCATCTGCGAATCCAGGGATTATGAAACCTAACTCACCTAATTTTACTGATAATCTG
GTGCCTGTCAGAGATGTGCCCAAAATAGCCATTAATGAGAAAGTGGTGGGTGGATATTCAAAAACCAAGC
CTACTACTCCTTTTGTGGCGTCGCTGTCTGGCACAACCTATTCTCTTATGGTGGTGTTAACGGACTATAT
TGAAAAGCATAAAACGGATAAAGACATTGAAAAAAAAGTAAACCAGATTATTAATTTATGGATTTCCAGT
TATATCAAGGAAGGTTATCACAGCTACAGTGAGGTTGTGGATGTTTTGACAGAGCCGTTTCTTCAATCCA
TTTTTGATAAAGCAAATATTAAATTAAATTACGGTGTACTAGACGACACGCATGCAGAATTTCGTAAAGC
TCAGGATTATGTTTTTGGTTTGACAATTCGAGCAGCAATGCATCATGAGTTACAAGAGCGATTTAAGAAT
AAAGAAAAACTTCAGGAAGAGGTAAAGAATTTTGAGTCTGGGTTAAATAAACTCAACCAGGATGTCGAAA
GTACAGGTCGCCATCGCGAGGCACTGAATAAATTAAACGAGGTATTTCAGGATTGGTCTGCGGGCAAAAA
AAGCTATGATGCTTTTAAAAGTGAGTCTAATCAACTGATTCGTGATATTGAATCTGAAGAACAAAAAAGT
AATCGTGGTCTTGGTTCGATGCTGAAGAACTTCGGAAACTATCTTTTATACTTGATTACCCTTCGTTTTT
TGAAAGAAGACTATCTAAAACCATCTAGTCCGGTCTCAATGTTAGTCACTGAATTAAGAGGGACACTTGA
GCAAATAGATAATTTTCATAAAAATAGCCTCTCTTTAAAAAAGGCAACGCAGCCTGACCCTAAAAATACT
TCACCATCTGTTGAGACATCAGATGTTCTGAAATCAGCTGTGGATAATGACAAGCTTAATAAAAACCAGG
ACAGTGAAGTAAAAAAGACATTAGATTCTGAGCAAATGGAGGAAGTTCAAAGGCAAGATGACAAAAGCGC
TCGGTTACAGTAG

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature