Effector Protein ID: 296108151 |
T4SS name [ID] | Dot/Icm [43] |
Gene symbol | sidC |
Locus tag | lpa_03669 |
Strain | Legionella pneumophila 2300/99 Alcoy |
Replicon | chromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 2948869..2951598 [+] |
Product | SidC Protein |
Effector type | Protein |
Descripton | SidC |
T4CP requirement | T4CP Depedent |
Target/Effection | SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole. (Ragaz et al, 2008) |
UniProt ID | D5T8Z9 |
KEGG ID | lpa:lpa_03669 |
PDB ID | NA |
Domain hit(s) vs Pfam | NA |
Protein Sequence: 909 a.a. [Download] |
>gi|296108151|ref|YP_003619852.1| SidC Protein [Legionella pneumophila 2300/99 Alcoy] MVDVIKFKEPERCDYLYIDENNKVHILLPIVGGDEIGLDNTCQTAVELITFFYGSAHSGVTKYSAEHQLS EYKRQLEEDIKAINSQKKISPHAYDDLLKEKKERLQQIEKYIELIQVLKGQNAEQDIRQLRTGGIPKLPA AVKEIIKSSENAFAVRLSPYDNDKFTRFDDPLFNVKRNISKYDTPSRQAPIPIYEGLGYRLRSTLFPKEK TPTPINKKSLREKVKSTVLSHYKEEDRIDGEKRDEKLSELITKLQNELVKELVKIDPQYSKLSLSKDPRG NEINYNYLVNSLMLVDDDSKIGEWIETILDSTVDSTVWEAQASSPFYDGAKEIKSDKEADRISIRVQYLL AEANIYCKTNKLSDANFGEFFDKEPHATEIAKRVKEGFTQGAEIEPIIYDYINNNHAELGLKSPLTGEQL QEITEKFTRHYNTIKESPHFDEFFVADPDKKGNIFCHQGRISCHFLDFFTRHTKGNYPLGDLANHQESLQ KGTSNRLHHKNELVAQGYERLDQFKKEVVKLLAEDKPKELLDYLLTNSPTGVPNYSMLSKETQNYIAYNR NWPAIQKELEQTTNIPENQKQDLLRLLSRDNLSHDNLSAITWSKYSSKPLLDVELNKIAEGLELTAKIYN EKRGSEWWFKGSRNQARNTQCEELQRVAKEINALLQNETLTKSQVLEKVLNSIETLDKIDRDISAESNWF KSTLQKEVRLFRDQLKDICQLDKYAFKSTKLDEIISLEMEEQFQKIEDPVVQKIVRDLPAHCHNDEAIEF FKTLNPEEAAKVASYLSLEYREINKSTDKKTLLEQDIPKLFKEVNALLLSKLKEEKAIDEQVHEKLSQLA DKIPPEHFTRNNIIKWSATPEKLEESNLNELIKSVESPTTKQTSKQFREAMGEITGRNEPPKDTLGHTI |
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Nucleotide Sequence: 2730 bp [Download] |
>gi|296105497|ref|NC_014125.1|:2948869-2951598 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome ATGGTTGACGTAATCAAATTCAAAGAGCCGGAACGTTGTGACTATCTATATATTGATGAAAACAACAAAG TTCATATCCTTTTACCGATTGTAGGAGGAGATGAAATAGGTCTGGATAACACCTGTCAAACAGCAGTTGA GTTGATCACATTTTTCTATGGTAGTGCGCACAGTGGTGTGACTAAATATTCTGCCGAACACCAACTCAGT GAATACAAAAGGCAATTGGAAGAAGACATCAAAGCCATCAATAGTCAAAAGAAAATTTCACCCCATGCTT ATGACGATTTATTAAAAGAGAAAAAAGAACGCCTGCAACAAATTGAAAAATACATTGAATTAATTCAAGT ATTAAAAGGTCAAAATGCTGAACAAGATATCAGGCAACTCCGTACCGGAGGAATCCCAAAATTGCCCGCT GCTGTAAAGGAAATCATTAAATCCTCTGAAAATGCTTTTGCTGTGAGGCTTTCTCCTTATGACAACGATA AATTTACTCGCTTTGATGACCCTTTATTCAATGTCAAAAGAAACATCTCTAAATACGATACGCCCTCAAG GCAAGCTCCTATTCCAATATACGAGGGATTAGGGTATCGCCTGCGTTCAACTCTGTTCCCGAAAGAGAAA ACACCGACTCCAATCAATAAAAAATCACTTAGAGAAAAAGTAAAAAGCACTGTTCTTAGTCATTATAAAG AGGAAGATAGAATTGATGGAGAAAAAAGAGATGAAAAATTAAGCGAGTTAATTACTAAACTTCAAAATGA ACTTGTAAAAGAGTTAGTAAAAATTGATCCTCAATATTCGAAGCTATCATTATCTAAAGATCCAAGAGGA AATGAAATAAATTACAATTATTTAGTTAATAGTTTAATGCTTGTAGATGACGACTCTAAAATTGGTGAGT GGATTGAAACGATTCTCGACTCTACAGTAGATTCGACTGTATGGGAAGCTCAAGCATCCAGCCCTTTCTA TGATGGCGCTAAAGAAATAAAATCAGACAAAGAAGCAGACAGGATATCCATCAGAGTTCAGTACCTGTTG GCGGAAGCAAACATTTATTGTAAAACAAACAAATTATCGGACGCTAACTTCGGAGAATTTTTCGACAAAG AGCCTCATGCTACTGAAATTGCGAAAAGAGTAAAGGAAGGATTTACGCAAGGTGCAGAGATAGAACCAAT TATATACGACTACATTAACAACAACCATGCTGAATTGGGATTAAAATCCCCGTTAACAGGCGAACAACTA CAAGAAATCACTGAGAAATTTACGAGACATTATAATACGATTAAGGAATCTCCTCATTTTGATGAGTTTT TTGTCGCAGATCCTGATAAAAAAGGCAATATCTTTTGTCATCAAGGCAGAATCAGTTGTCATTTTCTGGA TTTCTTTACTCGACATACCAAAGGCAATTATCCACTTGGTGATCTTGCAAATCATCAGGAATCTCTCCAA AAAGGAACCTCCAATCGGTTACATCACAAAAATGAGTTAGTAGCTCAGGGATATGAGAGACTGGATCAAT TCAAGAAAGAAGTTGTAAAACTACTGGCTGAGGATAAACCAAAAGAATTATTGGATTACTTGCTCACTAA CTCACCCACAGGTGTTCCAAATTACTCCATGCTTTCAAAGGAAACTCAAAATTACATTGCTTACAATCGT AACTGGCCAGCCATTCAAAAAGAGCTGGAACAGACTACCAACATACCAGAGAATCAAAAACAAGATCTCC TAAGATTGCTTTCTCGTGATAATCTGAGCCACGATAATCTAAGCGCAATTACCTGGTCAAAATATTCCTC CAAGCCATTATTGGATGTGGAATTAAACAAAATCGCTGAAGGATTAGAACTCACTGCAAAAATTTACAAT GAAAAAAGAGGAAGTGAATGGTGGTTTAAAGGTTCAAGAAATCAAGCTCGTAATACTCAATGTGAAGAAT TGCAAAGAGTGGCTAAAGAAATCAATGCTCTTTTGCAAAATGAAACTTTAACCAAAAGCCAGGTCCTTGA AAAAGTTTTAAACTCTATAGAAACATTGGATAAAATTGACAGAGACATTTCCGCCGAATCCAATTGGTTT AAAAGTACTTTGCAAAAGGAAGTCAGATTATTTCGGGATCAATTGAAAGATATTTGCCAATTGGATAAGT ATGCCTTTAAATCAACAAAACTTGATGAAATTATCTCTCTGGAAATGGAAGAACAATTTCAAAAGATAGA AGATCCTGTTGTTCAGAAAATTGTCAGGGACTTGCCTGCTCATTGCCACAATGATGAAGCAATTGAATTC TTTAAGACATTGAACCCTGAAGAGGCAGCTAAAGTGGCTAGCTATTTAAGCCTGGAATACCGGGAAATTA ATAAATCAACAGATAAGAAAACTCTCCTTGAGCAAGATATTCCCAAACTGTTTAAAGAAGTAAATGCACT ACTACTCTCCAAATTAAAAGAAGAAAAAGCCATTGATGAGCAAGTCCATGAAAAACTCAGTCAACTGGCT GACAAAATTCCTCCTGAGCATTTTACAAGAAATAACATTATAAAATGGTCTGCTACCCCTGAAAAGCTTG AGGAATCAAATCTTAATGAGCTAATCAAATCAGTCGAAAGCCCTACTACTAAACAAACATCAAAACAATT CAGGGAAGCCATGGGTGAAATCACTGGAAGAAATGAGCCTCCTAAAGACACCCTTGGGCATACAATATAG |
Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] |
in silico analysis literature |