SecReT4
Effector Protein ID: 296108151
T4SS name [ID]Dot/Icm [43]
Gene symbolsidC
Locus taglpa_03669
StrainLegionella pneumophila 2300/99 Alcoy
Repliconchromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon]
Location [Strand]2948869..2951598 [+]
ProductSidC Protein
Effector typeProtein
DescriptonSidC
T4CP requirementT4CP Depedent
Target/EffectionSidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole. (Ragaz et al, 2008)
UniProt IDD5T8Z9
KEGG IDlpa:lpa_03669
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 909 a.a.     [Download]
>gi|296108151|ref|YP_003619852.1| SidC Protein [Legionella pneumophila 2300/99 Alcoy]
MVDVIKFKEPERCDYLYIDENNKVHILLPIVGGDEIGLDNTCQTAVELITFFYGSAHSGVTKYSAEHQLS
EYKRQLEEDIKAINSQKKISPHAYDDLLKEKKERLQQIEKYIELIQVLKGQNAEQDIRQLRTGGIPKLPA
AVKEIIKSSENAFAVRLSPYDNDKFTRFDDPLFNVKRNISKYDTPSRQAPIPIYEGLGYRLRSTLFPKEK
TPTPINKKSLREKVKSTVLSHYKEEDRIDGEKRDEKLSELITKLQNELVKELVKIDPQYSKLSLSKDPRG
NEINYNYLVNSLMLVDDDSKIGEWIETILDSTVDSTVWEAQASSPFYDGAKEIKSDKEADRISIRVQYLL
AEANIYCKTNKLSDANFGEFFDKEPHATEIAKRVKEGFTQGAEIEPIIYDYINNNHAELGLKSPLTGEQL
QEITEKFTRHYNTIKESPHFDEFFVADPDKKGNIFCHQGRISCHFLDFFTRHTKGNYPLGDLANHQESLQ
KGTSNRLHHKNELVAQGYERLDQFKKEVVKLLAEDKPKELLDYLLTNSPTGVPNYSMLSKETQNYIAYNR
NWPAIQKELEQTTNIPENQKQDLLRLLSRDNLSHDNLSAITWSKYSSKPLLDVELNKIAEGLELTAKIYN
EKRGSEWWFKGSRNQARNTQCEELQRVAKEINALLQNETLTKSQVLEKVLNSIETLDKIDRDISAESNWF
KSTLQKEVRLFRDQLKDICQLDKYAFKSTKLDEIISLEMEEQFQKIEDPVVQKIVRDLPAHCHNDEAIEF
FKTLNPEEAAKVASYLSLEYREINKSTDKKTLLEQDIPKLFKEVNALLLSKLKEEKAIDEQVHEKLSQLA
DKIPPEHFTRNNIIKWSATPEKLEESNLNELIKSVESPTTKQTSKQFREAMGEITGRNEPPKDTLGHTI
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Nucleotide Sequence: 2730 bp     [Download]
>gi|296105497|ref|NC_014125.1|:2948869-2951598 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome
ATGGTTGACGTAATCAAATTCAAAGAGCCGGAACGTTGTGACTATCTATATATTGATGAAAACAACAAAG
TTCATATCCTTTTACCGATTGTAGGAGGAGATGAAATAGGTCTGGATAACACCTGTCAAACAGCAGTTGA
GTTGATCACATTTTTCTATGGTAGTGCGCACAGTGGTGTGACTAAATATTCTGCCGAACACCAACTCAGT
GAATACAAAAGGCAATTGGAAGAAGACATCAAAGCCATCAATAGTCAAAAGAAAATTTCACCCCATGCTT
ATGACGATTTATTAAAAGAGAAAAAAGAACGCCTGCAACAAATTGAAAAATACATTGAATTAATTCAAGT
ATTAAAAGGTCAAAATGCTGAACAAGATATCAGGCAACTCCGTACCGGAGGAATCCCAAAATTGCCCGCT
GCTGTAAAGGAAATCATTAAATCCTCTGAAAATGCTTTTGCTGTGAGGCTTTCTCCTTATGACAACGATA
AATTTACTCGCTTTGATGACCCTTTATTCAATGTCAAAAGAAACATCTCTAAATACGATACGCCCTCAAG
GCAAGCTCCTATTCCAATATACGAGGGATTAGGGTATCGCCTGCGTTCAACTCTGTTCCCGAAAGAGAAA
ACACCGACTCCAATCAATAAAAAATCACTTAGAGAAAAAGTAAAAAGCACTGTTCTTAGTCATTATAAAG
AGGAAGATAGAATTGATGGAGAAAAAAGAGATGAAAAATTAAGCGAGTTAATTACTAAACTTCAAAATGA
ACTTGTAAAAGAGTTAGTAAAAATTGATCCTCAATATTCGAAGCTATCATTATCTAAAGATCCAAGAGGA
AATGAAATAAATTACAATTATTTAGTTAATAGTTTAATGCTTGTAGATGACGACTCTAAAATTGGTGAGT
GGATTGAAACGATTCTCGACTCTACAGTAGATTCGACTGTATGGGAAGCTCAAGCATCCAGCCCTTTCTA
TGATGGCGCTAAAGAAATAAAATCAGACAAAGAAGCAGACAGGATATCCATCAGAGTTCAGTACCTGTTG
GCGGAAGCAAACATTTATTGTAAAACAAACAAATTATCGGACGCTAACTTCGGAGAATTTTTCGACAAAG
AGCCTCATGCTACTGAAATTGCGAAAAGAGTAAAGGAAGGATTTACGCAAGGTGCAGAGATAGAACCAAT
TATATACGACTACATTAACAACAACCATGCTGAATTGGGATTAAAATCCCCGTTAACAGGCGAACAACTA
CAAGAAATCACTGAGAAATTTACGAGACATTATAATACGATTAAGGAATCTCCTCATTTTGATGAGTTTT
TTGTCGCAGATCCTGATAAAAAAGGCAATATCTTTTGTCATCAAGGCAGAATCAGTTGTCATTTTCTGGA
TTTCTTTACTCGACATACCAAAGGCAATTATCCACTTGGTGATCTTGCAAATCATCAGGAATCTCTCCAA
AAAGGAACCTCCAATCGGTTACATCACAAAAATGAGTTAGTAGCTCAGGGATATGAGAGACTGGATCAAT
TCAAGAAAGAAGTTGTAAAACTACTGGCTGAGGATAAACCAAAAGAATTATTGGATTACTTGCTCACTAA
CTCACCCACAGGTGTTCCAAATTACTCCATGCTTTCAAAGGAAACTCAAAATTACATTGCTTACAATCGT
AACTGGCCAGCCATTCAAAAAGAGCTGGAACAGACTACCAACATACCAGAGAATCAAAAACAAGATCTCC
TAAGATTGCTTTCTCGTGATAATCTGAGCCACGATAATCTAAGCGCAATTACCTGGTCAAAATATTCCTC
CAAGCCATTATTGGATGTGGAATTAAACAAAATCGCTGAAGGATTAGAACTCACTGCAAAAATTTACAAT
GAAAAAAGAGGAAGTGAATGGTGGTTTAAAGGTTCAAGAAATCAAGCTCGTAATACTCAATGTGAAGAAT
TGCAAAGAGTGGCTAAAGAAATCAATGCTCTTTTGCAAAATGAAACTTTAACCAAAAGCCAGGTCCTTGA
AAAAGTTTTAAACTCTATAGAAACATTGGATAAAATTGACAGAGACATTTCCGCCGAATCCAATTGGTTT
AAAAGTACTTTGCAAAAGGAAGTCAGATTATTTCGGGATCAATTGAAAGATATTTGCCAATTGGATAAGT
ATGCCTTTAAATCAACAAAACTTGATGAAATTATCTCTCTGGAAATGGAAGAACAATTTCAAAAGATAGA
AGATCCTGTTGTTCAGAAAATTGTCAGGGACTTGCCTGCTCATTGCCACAATGATGAAGCAATTGAATTC
TTTAAGACATTGAACCCTGAAGAGGCAGCTAAAGTGGCTAGCTATTTAAGCCTGGAATACCGGGAAATTA
ATAAATCAACAGATAAGAAAACTCTCCTTGAGCAAGATATTCCCAAACTGTTTAAAGAAGTAAATGCACT
ACTACTCTCCAAATTAAAAGAAGAAAAAGCCATTGATGAGCAAGTCCATGAAAAACTCAGTCAACTGGCT
GACAAAATTCCTCCTGAGCATTTTACAAGAAATAACATTATAAAATGGTCTGCTACCCCTGAAAAGCTTG
AGGAATCAAATCTTAATGAGCTAATCAAATCAGTCGAAAGCCCTACTACTAAACAAACATCAAAACAATT
CAGGGAAGCCATGGGTGAAATCACTGGAAGAAATGAGCCTCCTAAAGACACCCTTGGGCATACAATATAG

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature