Effector Protein ID: 296108150 |
T4SS name [ID] | Dot/Icm [43] |
Gene symbol | - |
Locus tag | lpa_03668 |
Strain | Legionella pneumophila 2300/99 Alcoy |
Replicon | chromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 2945983..2948706 [+] |
Product | SdcA |
Effector type | Protein |
Descripton | SdcA |
T4CP requirement | T4CP Depedent |
Target/Effection | A paralog of sidC which is important for Legionella-containing vacuole recruitment of endoplasmic reticulum -derived vesicles |
UniProt ID | D5T8Z8 |
KEGG ID | lpa:lpa_03668 |
PDB ID | NA |
Domain hit(s) vs Pfam | NA |
Protein Sequence: 907 a.a. [Download] |
>gi|296108150|ref|YP_003619851.1| SdcA [Legionella pneumophila 2300/99 Alcoy] MNMVDKIKFKEPERCEYLHIDKDNKVHILLPIVGGDEIGLDNTCETTGELLAFFYGKTHGGTKYSAEHHL NEYKKNLEDDIKAIGVQRKISPNAYEDLLKEKKERLEQIEKYIDLIKVLKEKFDEQREIDKLRTEGIPQL PSGVKEVIKSSKNAFALRLSPDRPDSFTRFDDPLFSLKRNRSQYEAGGYQRATDGLGARLRSELLPPDKD TPIVFNKKSMKDKIVDSVLAQLDKDFNTKDGDRDQKFEDIKKLVLEEYKKIDSELQVDEDTYHQPLNLDY LENIACTLDDNSTAKDWVYGIIGATTEADYWPKKESESGTEKVSVFYEKQKEIKFESDTNTMSIKVQYLL AEINFYCKANKLSDANFGEFFDKEPHATEVAKRVKEGLVQGAEIEPIIYNYINSHYAELGLTSQLSSKQR EEITEKFTQRYHIIENSPHFDEFFVADPDKKGNIFSHQGRMSCHFLDFFARQTKGKHPLGDLAGHQEALQ AGTSNRLHHKNEIVAQGYEKFDQFKKEVVKLLAESKPKELLDYLVATSPTGVPNYSMLSKETQNYIAYNR NWPAIQKELEKTTDIPENQKQDLLRLLSRNNLQYDNLSAITWSKYSSKPLLDVELNKIAEGLDLTAKIYN EKRKSEWFKGSRNRARKTQCEELQRVSQEINALLQSESLTKSQVLEKVLNSIEALDKIDRDISAEYNLFN STLQKEVQLFRDQLKDICQLDNYAFKSIKLDEIISLEMEEQFQMIKDPAIQQIVRDLPSHCHNNEAIEFF MTLNPEEAAKVASYLSLEYRELNKSTDKKTLLEQDIPKLFKEVNMQLLSQLKQDSAVKEDVFEKLSQLAD KIPPEHFTRNNIRKWSANPEKLEESNLGELLKSSDSSLTEMARKYRDTINEMTRRNEPPRETVRHTI |
- |
Nucleotide Sequence: 2724 bp [Download] |
>gi|296105497|ref|NC_014125.1|:2945983-2948706 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome ATGAACATGGTTGACAAAATAAAATTCAAAGAGCCAGAGCGATGCGAATATTTACATATCGATAAGGATA ATAAAGTCCATATTCTTTTACCTATTGTAGGTGGGGATGAAATAGGACTGGATAATACCTGTGAAACAAC AGGTGAGTTATTAGCCTTTTTCTATGGAAAAACGCATGGTGGGACAAAGTATTCTGCTGAACATCACCTA AATGAATATAAAAAGAACCTGGAAGATGATATAAAAGCAATCGGTGTTCAAAGAAAAATTTCACCAAACG CCTACGAAGATCTATTAAAGGAGAAAAAAGAACGCCTGGAACAAATCGAAAAATATATTGATTTAATCAA AGTACTCAAAGAGAAATTTGATGAGCAAAGAGAAATAGACAAACTACGCACAGAAGGAATCCCGCAATTA CCTTCTGGAGTAAAGGAAGTCATTAAATCTTCTAAAAATGCCTTTGCTTTAAGGCTTTCCCCGGATAGAC CAGACTCATTTACTCGCTTTGATGATCCTCTGTTTAGTCTCAAAAGAAACAGATCTCAATATGAAGCTGG GGGATACCAACGGGCAACTGATGGATTAGGGGCTCGTTTGCGTTCTGAGCTTCTACCACCAGATAAAGAC ACTCCTATTGTTTTTAATAAAAAATCAATGAAGGACAAAATCGTAGATTCTGTTTTAGCGCAACTTGACA AAGATTTTAATACAAAAGATGGCGATCGTGATCAAAAATTTGAGGATATAAAAAAACTCGTTCTAGAAGA GTACAAGAAAATTGATTCCGAACTTCAAGTGGACGAGGATACCTATCACCAGCCACTTAACTTGGATTAT TTGGAAAACATAGCATGTACGTTAGATGACAACTCCACCGCAAAAGATTGGGTTTATGGAATTATTGGCG CTACAACAGAAGCTGATTATTGGCCAAAAAAGGAAAGTGAAAGTGGGACTGAAAAAGTTAGTGTATTCTA TGAGAAGCAAAAGGAAATAAAATTTGAATCTGATACAAATACAATGTCAATTAAAGTCCAATATCTATTG GCTGAGATTAATTTTTATTGTAAAGCCAACAAATTATCAGATGCTAACTTCGGTGAATTTTTTGATAAAG AGCCCCATGCTACTGAAGTAGCCAAAAGAGTGAAAGAAGGACTTGTTCAAGGAGCAGAGATTGAGCCTAT TATTTACAATTACATTAACAGCCACTACGCCGAACTGGGATTAACATCTCAGTTAAGCAGCAAGCAACGA GAGGAAATTACTGAAAAATTTACTCAACGTTATCACATTATTGAGAACTCGCCTCACTTTGATGAATTTT TTGTCGCTGATCCTGATAAAAAAGGGAATATATTCTCCCATCAAGGCAGAATGAGTTGTCATTTCCTGGA TTTCTTCGCTCGACAAACCAAAGGCAAACATCCCCTTGGTGATCTTGCAGGTCATCAGGAAGCACTCCAG GCAGGAACTTCCAATCGGTTACATCACAAGAATGAGATAGTCGCTCAAGGATACGAAAAATTTGATCAAT TCAAGAAAGAAGTCGTCAAACTGCTGGCAGAGAGTAAACCAAAAGAATTATTGGATTATTTGGTTGCTAC CTCCCCAACAGGTGTTCCTAATTATTCCATGCTCTCAAAGGAAACTCAAAATTATATTGCTTACAACCGT AACTGGCCAGCCATTCAAAAAGAGCTTGAAAAAACTACTGACATACCAGAGAACCAAAAACAAGATCTTT TAAGATTGCTTTCTCGTAATAATCTGCAATACGATAATCTCAGTGCAATTACCTGGTCAAAATATTCTTC CAAGCCATTATTGGATGTGGAATTAAATAAAATTGCCGAAGGTTTAGATCTAACTGCTAAAATTTACAAT GAAAAAAGAAAAAGTGAATGGTTTAAAGGTTCAAGAAATAGGGCTCGTAAGACCCAATGCGAAGAATTGC AAAGAGTATCTCAAGAAATCAATGCTCTTCTACAAAGTGAATCGTTAACAAAAAGCCAAGTTCTTGAAAA AGTTTTAAACTCCATAGAAGCATTGGATAAAATTGATAGAGACATTTCTGCTGAATATAATTTATTTAAT AGTACTCTGCAAAAAGAAGTGCAATTATTTCGAGATCAATTGAAGGATATCTGTCAATTAGATAACTATG CCTTTAAATCAATAAAACTTGATGAAATTATCTCTCTGGAAATGGAAGAGCAATTTCAAATGATTAAAGA TCCTGCTATCCAACAAATTGTCCGAGACTTGCCTTCTCATTGTCATAATAATGAAGCGATTGAATTCTTT ATGACATTGAATCCTGAAGAAGCAGCTAAGGTAGCTAGCTATTTAAGCCTCGAGTACCGGGAACTCAATA AATCAACAGATAAGAAAACTCTCCTTGAACAAGATATTCCTAAATTATTTAAAGAAGTGAATATGCAACT GTTATCCCAGTTAAAACAAGATAGTGCCGTTAAGGAAGACGTCTTTGAAAAACTCAGTCAACTAGCTGAC AAAATACCTCCCGAACATTTTACAAGGAATAATATCAGGAAATGGTCTGCCAATCCTGAAAAGCTTGAGG AGTCCAATCTCGGCGAATTATTAAAATCATCTGATAGCTCACTTACTGAAATGGCAAGAAAATATAGAGA CACCATAAATGAAATGACAAGAAGAAATGAGCCACCCAGGGAAACCGTTAGACACACGATATAG |
Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] |
in silico analysis literature |