SecReT4
Effector Protein ID: 296108150
T4SS name [ID]Dot/Icm [43]
Gene symbol-
Locus taglpa_03668
StrainLegionella pneumophila 2300/99 Alcoy
Repliconchromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon]
Location [Strand]2945983..2948706 [+]
ProductSdcA
Effector typeProtein
DescriptonSdcA
T4CP requirementT4CP Depedent
Target/EffectionA paralog of sidC which is important for Legionella-containing vacuole recruitment of endoplasmic reticulum -derived vesicles
UniProt IDD5T8Z8
KEGG IDlpa:lpa_03668
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 907 a.a.     [Download]
>gi|296108150|ref|YP_003619851.1| SdcA [Legionella pneumophila 2300/99 Alcoy]
MNMVDKIKFKEPERCEYLHIDKDNKVHILLPIVGGDEIGLDNTCETTGELLAFFYGKTHGGTKYSAEHHL
NEYKKNLEDDIKAIGVQRKISPNAYEDLLKEKKERLEQIEKYIDLIKVLKEKFDEQREIDKLRTEGIPQL
PSGVKEVIKSSKNAFALRLSPDRPDSFTRFDDPLFSLKRNRSQYEAGGYQRATDGLGARLRSELLPPDKD
TPIVFNKKSMKDKIVDSVLAQLDKDFNTKDGDRDQKFEDIKKLVLEEYKKIDSELQVDEDTYHQPLNLDY
LENIACTLDDNSTAKDWVYGIIGATTEADYWPKKESESGTEKVSVFYEKQKEIKFESDTNTMSIKVQYLL
AEINFYCKANKLSDANFGEFFDKEPHATEVAKRVKEGLVQGAEIEPIIYNYINSHYAELGLTSQLSSKQR
EEITEKFTQRYHIIENSPHFDEFFVADPDKKGNIFSHQGRMSCHFLDFFARQTKGKHPLGDLAGHQEALQ
AGTSNRLHHKNEIVAQGYEKFDQFKKEVVKLLAESKPKELLDYLVATSPTGVPNYSMLSKETQNYIAYNR
NWPAIQKELEKTTDIPENQKQDLLRLLSRNNLQYDNLSAITWSKYSSKPLLDVELNKIAEGLDLTAKIYN
EKRKSEWFKGSRNRARKTQCEELQRVSQEINALLQSESLTKSQVLEKVLNSIEALDKIDRDISAEYNLFN
STLQKEVQLFRDQLKDICQLDNYAFKSIKLDEIISLEMEEQFQMIKDPAIQQIVRDLPSHCHNNEAIEFF
MTLNPEEAAKVASYLSLEYRELNKSTDKKTLLEQDIPKLFKEVNMQLLSQLKQDSAVKEDVFEKLSQLAD
KIPPEHFTRNNIRKWSANPEKLEESNLGELLKSSDSSLTEMARKYRDTINEMTRRNEPPRETVRHTI
-
Nucleotide Sequence: 2724 bp     [Download]
>gi|296105497|ref|NC_014125.1|:2945983-2948706 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome
ATGAACATGGTTGACAAAATAAAATTCAAAGAGCCAGAGCGATGCGAATATTTACATATCGATAAGGATA
ATAAAGTCCATATTCTTTTACCTATTGTAGGTGGGGATGAAATAGGACTGGATAATACCTGTGAAACAAC
AGGTGAGTTATTAGCCTTTTTCTATGGAAAAACGCATGGTGGGACAAAGTATTCTGCTGAACATCACCTA
AATGAATATAAAAAGAACCTGGAAGATGATATAAAAGCAATCGGTGTTCAAAGAAAAATTTCACCAAACG
CCTACGAAGATCTATTAAAGGAGAAAAAAGAACGCCTGGAACAAATCGAAAAATATATTGATTTAATCAA
AGTACTCAAAGAGAAATTTGATGAGCAAAGAGAAATAGACAAACTACGCACAGAAGGAATCCCGCAATTA
CCTTCTGGAGTAAAGGAAGTCATTAAATCTTCTAAAAATGCCTTTGCTTTAAGGCTTTCCCCGGATAGAC
CAGACTCATTTACTCGCTTTGATGATCCTCTGTTTAGTCTCAAAAGAAACAGATCTCAATATGAAGCTGG
GGGATACCAACGGGCAACTGATGGATTAGGGGCTCGTTTGCGTTCTGAGCTTCTACCACCAGATAAAGAC
ACTCCTATTGTTTTTAATAAAAAATCAATGAAGGACAAAATCGTAGATTCTGTTTTAGCGCAACTTGACA
AAGATTTTAATACAAAAGATGGCGATCGTGATCAAAAATTTGAGGATATAAAAAAACTCGTTCTAGAAGA
GTACAAGAAAATTGATTCCGAACTTCAAGTGGACGAGGATACCTATCACCAGCCACTTAACTTGGATTAT
TTGGAAAACATAGCATGTACGTTAGATGACAACTCCACCGCAAAAGATTGGGTTTATGGAATTATTGGCG
CTACAACAGAAGCTGATTATTGGCCAAAAAAGGAAAGTGAAAGTGGGACTGAAAAAGTTAGTGTATTCTA
TGAGAAGCAAAAGGAAATAAAATTTGAATCTGATACAAATACAATGTCAATTAAAGTCCAATATCTATTG
GCTGAGATTAATTTTTATTGTAAAGCCAACAAATTATCAGATGCTAACTTCGGTGAATTTTTTGATAAAG
AGCCCCATGCTACTGAAGTAGCCAAAAGAGTGAAAGAAGGACTTGTTCAAGGAGCAGAGATTGAGCCTAT
TATTTACAATTACATTAACAGCCACTACGCCGAACTGGGATTAACATCTCAGTTAAGCAGCAAGCAACGA
GAGGAAATTACTGAAAAATTTACTCAACGTTATCACATTATTGAGAACTCGCCTCACTTTGATGAATTTT
TTGTCGCTGATCCTGATAAAAAAGGGAATATATTCTCCCATCAAGGCAGAATGAGTTGTCATTTCCTGGA
TTTCTTCGCTCGACAAACCAAAGGCAAACATCCCCTTGGTGATCTTGCAGGTCATCAGGAAGCACTCCAG
GCAGGAACTTCCAATCGGTTACATCACAAGAATGAGATAGTCGCTCAAGGATACGAAAAATTTGATCAAT
TCAAGAAAGAAGTCGTCAAACTGCTGGCAGAGAGTAAACCAAAAGAATTATTGGATTATTTGGTTGCTAC
CTCCCCAACAGGTGTTCCTAATTATTCCATGCTCTCAAAGGAAACTCAAAATTATATTGCTTACAACCGT
AACTGGCCAGCCATTCAAAAAGAGCTTGAAAAAACTACTGACATACCAGAGAACCAAAAACAAGATCTTT
TAAGATTGCTTTCTCGTAATAATCTGCAATACGATAATCTCAGTGCAATTACCTGGTCAAAATATTCTTC
CAAGCCATTATTGGATGTGGAATTAAATAAAATTGCCGAAGGTTTAGATCTAACTGCTAAAATTTACAAT
GAAAAAAGAAAAAGTGAATGGTTTAAAGGTTCAAGAAATAGGGCTCGTAAGACCCAATGCGAAGAATTGC
AAAGAGTATCTCAAGAAATCAATGCTCTTCTACAAAGTGAATCGTTAACAAAAAGCCAAGTTCTTGAAAA
AGTTTTAAACTCCATAGAAGCATTGGATAAAATTGATAGAGACATTTCTGCTGAATATAATTTATTTAAT
AGTACTCTGCAAAAAGAAGTGCAATTATTTCGAGATCAATTGAAGGATATCTGTCAATTAGATAACTATG
CCTTTAAATCAATAAAACTTGATGAAATTATCTCTCTGGAAATGGAAGAGCAATTTCAAATGATTAAAGA
TCCTGCTATCCAACAAATTGTCCGAGACTTGCCTTCTCATTGTCATAATAATGAAGCGATTGAATTCTTT
ATGACATTGAATCCTGAAGAAGCAGCTAAGGTAGCTAGCTATTTAAGCCTCGAGTACCGGGAACTCAATA
AATCAACAGATAAGAAAACTCTCCTTGAACAAGATATTCCTAAATTATTTAAAGAAGTGAATATGCAACT
GTTATCCCAGTTAAAACAAGATAGTGCCGTTAAGGAAGACGTCTTTGAAAAACTCAGTCAACTAGCTGAC
AAAATACCTCCCGAACATTTTACAAGGAATAATATCAGGAAATGGTCTGCCAATCCTGAAAAGCTTGAGG
AGTCCAATCTCGGCGAATTATTAAAATCATCTGATAGCTCACTTACTGAAATGGCAAGAAAATATAGAGA
CACCATAAATGAAATGACAAGAAGAAATGAGCCACCCAGGGAAACCGTTAGACACACGATATAG

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature