| Effector Protein ID: 296108142 |
 T4SS name [ID] | Dot/Icm [43] |
| Gene symbol | - |
| Locus tag | lpa_03658 |
| Strain | Legionella pneumophila 2300/99 Alcoy |
| Replicon | chromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2935516..2938344 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | SidI/ceg32 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | SidI interacts with eEF1A and eEF1Bgamma and inhibits protein synthesis. SidI is also involved in a stress response of eukaryotic cell (Belyi, et al. 2011) |
| UniProt ID | D5T8Z0 |
| KEGG ID | lpa:lpa_03658 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 942 a.a. [Download] |
| >gi|296108142|ref|YP_003619843.1| hypothetical protein lpa_03658 [Legionella pneumophila 2300/99 Alcoy] MTKIYLLTAPFDEEAKTGDGQYAASLELGFAENYEHIPCKWLKKDKGDYSIPFPTGTTSIPEETIPSAMV LQPVANENTIISGYKLKDAVSSPEKAQEVNNKTVSPRTPKIIVKHDNSLQSLTIMDIYSQKAIQFDESKV DEIINSLETKKDKLEKAIEDNNVDLSKIKKQKSKLAYLTRLYKENKENIQDNCTLNEYIEAHLFNPKFLS RHEKALNNFKALKSQFTGPVNLKELEKLTDKLTGIKEYSYDFHSNSLPYDLEHDKSFRNFYDFDGLKESI ENIIKELEVLNGIRQAVSDKYPNCFKALNETEEHDDKLKFINIIFNDGFSTTYDQQTFIKALSALDVEKA IDAYTNVKKKLENTQDIIANKEGGRNKLISELQTLIANKQEPYLSANEKLGGFYSKRKLSASEGFHLAYQ ANRRDPIKPEVIENIITKMKPIDEDTHLDIHIRPPDCGVFITPEDIKKFQEAGIKVNITIHEYKQNYTRR YLQQYTHDLMRQANSVQFFNATDRENAIIAATYGDCDKRNTTEPTGVAKKIREVGEDFDLDKYPVQKYDL KGKSGLTVASQKLSTEPDHPLDVVAKAPNILSFGTIRPGKGFEEALKLAQLIKDNSLSIDEKIKRVPIVK LAGDPQDKALMKQIVIERFGKTAVKTYQKTHPYDNQFNNSQRRDYWKNLVRELNAKVKEEGAVLNNPYIE IYPWCEPHELLALKQNCKYVCRMDDMGMRNNGSAIISVLDVGVVYTKFGSVTDDIFIKGGKYGNAVDIGE YRYGKYSLLKKEKEFKEQHEEEPLPKWLIKNPDSAYKRQSESRDPKDILDSIVAREENQLICDNIEDSDN YRTVVEAQKLLKERFTLKNAVDHLLENIGLGHLIAQEEVDELFETVDPVQAQIDNLDVLSDIKTPRLCLS RSCPELGFFGSRRGDLETKQENNKLKESILVF |
| - |
| Nucleotide Sequence: 2829 bp [Download] |
| >gi|296105497|ref|NC_014125.1|:2935516-2938344 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome ATGACTAAAATATACTTATTAACCGCACCTTTTGATGAAGAGGCAAAAACAGGTGATGGGCAATACGCGG CCTCTTTAGAATTGGGTTTTGCTGAAAATTACGAACATATCCCCTGTAAATGGTTAAAAAAAGATAAAGG TGATTACAGTATTCCATTCCCAACAGGAACTACTTCCATACCGGAAGAAACGATACCAAGCGCGATGGTA TTACAGCCAGTTGCTAACGAAAATACCATCATAAGCGGTTATAAATTAAAAGATGCTGTTTCGTCTCCAG AAAAAGCACAGGAAGTAAATAACAAAACGGTTAGTCCCAGAACGCCCAAAATTATTGTAAAGCATGATAA CAGCCTGCAATCACTTACAATAATGGATATTTACTCTCAAAAAGCTATCCAATTTGATGAGTCAAAAGTT GATGAAATAATTAACTCTTTAGAAACAAAAAAAGATAAACTGGAAAAAGCTATAGAAGATAATAACGTTG ATCTGAGTAAAATTAAGAAACAAAAATCCAAATTAGCGTATCTGACTAGATTATATAAAGAAAACAAAGA GAATATTCAAGATAATTGCACCTTAAATGAATATATTGAGGCACATTTATTTAATCCTAAATTTTTAAGC AGGCATGAGAAAGCACTTAATAATTTTAAGGCGCTTAAAAGCCAATTTACTGGCCCTGTCAATTTAAAAG AACTGGAAAAATTAACAGATAAACTGACTGGAATTAAAGAGTACAGCTATGATTTCCATAGTAACAGTTT ACCCTATGATTTAGAGCACGATAAAAGTTTCAGAAATTTTTATGATTTTGATGGATTAAAAGAATCTATT GAAAACATTATCAAGGAATTAGAGGTACTTAACGGCATTCGTCAGGCTGTATCAGACAAGTATCCCAATT GCTTTAAAGCGCTAAATGAAACAGAAGAGCACGACGATAAATTAAAATTTATCAATATTATTTTCAACGA TGGGTTTAGCACCACTTATGACCAACAAACCTTTATCAAGGCCTTATCAGCTCTTGATGTTGAAAAGGCA ATTGACGCTTATACAAATGTTAAAAAGAAACTGGAAAACACTCAGGATATTATCGCCAATAAAGAGGGGG GTAGAAATAAGTTAATTTCAGAATTACAAACTTTAATAGCAAATAAACAAGAACCTTACCTCTCTGCAAA TGAAAAGCTTGGCGGTTTTTACAGTAAAAGAAAACTCTCTGCAAGTGAAGGATTTCATTTAGCCTATCAG GCAAACCGACGTGACCCGATAAAACCTGAAGTGATTGAAAACATTATTACCAAAATGAAACCCATTGATG AGGATACTCATCTTGATATTCATATTCGCCCACCAGATTGCGGGGTCTTTATTACTCCAGAAGACATCAA AAAATTTCAAGAGGCTGGTATTAAAGTCAATATCACAATCCATGAATATAAACAGAACTACACTCGGCGT TATTTACAACAATATACTCATGATTTAATGCGCCAGGCAAACAGCGTGCAATTCTTTAATGCAACAGATA GGGAAAATGCTATTATTGCCGCTACTTATGGTGATTGTGATAAGCGCAATACAACTGAACCGACTGGTGT TGCAAAAAAAATAAGAGAAGTTGGGGAAGATTTTGACTTAGATAAATACCCGGTTCAAAAATATGATTTA AAAGGAAAATCAGGATTAACCGTTGCATCACAAAAATTAAGTACCGAACCGGATCATCCATTGGATGTAG TAGCCAAGGCCCCTAATATCTTATCTTTTGGTACGATTCGTCCTGGCAAAGGGTTTGAAGAAGCGTTAAA GCTGGCTCAATTGATCAAAGATAACTCTCTTTCTATTGATGAAAAAATAAAACGGGTACCTATTGTAAAA CTGGCTGGTGACCCACAAGACAAAGCTTTAATGAAACAAATAGTTATTGAAAGGTTTGGTAAAACAGCGG TCAAAACTTATCAAAAAACTCATCCCTATGATAATCAATTCAATAATAGTCAGCGCAGAGATTATTGGAA AAATTTGGTTAGGGAGTTAAATGCAAAAGTTAAAGAAGAAGGCGCTGTTCTTAATAATCCTTACATCGAA ATTTATCCTTGGTGTGAGCCGCATGAATTGCTGGCTTTAAAGCAAAACTGTAAATACGTTTGTCGAATGG ACGACATGGGCATGAGAAACAATGGCTCAGCAATTATCAGTGTATTAGACGTTGGAGTCGTTTATACTAA ATTTGGTTCTGTTACAGACGATATTTTCATTAAGGGCGGCAAATACGGCAATGCCGTTGATATTGGAGAA TATCGTTATGGTAAATACAGTCTGTTAAAAAAAGAAAAGGAATTTAAAGAACAACATGAGGAAGAACCAC TACCTAAGTGGCTAATCAAAAATCCAGACTCTGCTTATAAGCGACAATCAGAATCGAGAGATCCAAAGGA TATTTTAGACTCCATTGTCGCAAGAGAAGAAAATCAATTAATATGTGATAATATAGAAGATTCCGATAAT TATCGAACAGTAGTCGAAGCACAAAAGTTATTAAAAGAGCGCTTTACACTCAAAAATGCTGTAGATCATT TATTAGAGAATATAGGACTCGGCCATTTAATTGCTCAAGAAGAAGTCGATGAATTATTTGAGACAGTTGA TCCAGTGCAAGCACAAATAGATAATTTAGACGTTCTTTCTGATATTAAGACACCACGTCTGTGTTTATCA CGCTCTTGCCCTGAGCTAGGTTTTTTCGGCTCACGTCGTGGTGACTTAGAGACTAAACAAGAAAATAATA AACTTAAAGAATCGATACTGGTATTTTGA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |