Effector Protein ID: 296107809 |
T4SS name [ID] | Dot/Icm [43] |
Gene symbol | - |
Locus tag | lpa_03191 |
Strain | Legionella pneumophila 2300/99 Alcoy |
Replicon | chromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 2600285..2601412 [-] |
Product | TPR repeat protein, protein-protein interaction |
Effector type | Protein |
Descripton | LpnE |
T4CP requirement | T4CP Depedent |
Target/Effection | Vacuolar trafficking |
UniProt ID | D5T6V7 |
KEGG ID | lpa:lpa_03191 |
PDB ID | NA |
Domain hit(s) vs Pfam | Sel1 [PF08238], Evalue: 6.2e-75, Aligned region: 52..87 Sel1 [PF08238], Evalue: 6.2e-75, Aligned region: 89..122 Sel1 [PF08238], Evalue: 6.2e-75, Aligned region: 123..158 Sel1 [PF08238], Evalue: 6.2e-75, Aligned region: 160..194 Sel1 [PF08238], Evalue: 6.2e-75, Aligned region: 195..230 Sel1 [PF08238], Evalue: 6.2e-75, Aligned region: 231..266 Sel1 [PF08238], Evalue: 6.2e-75, Aligned region: 267..302 Sel1 [PF08238], Evalue: 6.2e-75, Aligned region: 304..337 |
Protein Sequence: 375 a.a. [Download] |
>gi|296107809|ref|YP_003619510.1| TPR repeat protein, protein-protein interaction [Legionella pneumophila 2300/99 Alcoy] MDMKKYILSLSLLTVLNSSAIATTQEGEEAYNKGYYEKAFILLSPEADKGDAKAQYLLGKMYYNAQGVTY NPEKTEQLLLASANQGNVDAQVLLAGFYWYLNTPDGYKKAFEWYQKAADQNNADGQYGLGYMYDTGTGVP QNSDTAMVWYKKAAEQGNSNAALAIGYNYDTGTGVKKDKTQALNWYAKAADLGNASAQYNLGLMYEQGDG VPKDYQKAAEYFEKAANQDHAKSQLELGYLYDSGKLGKSDLQKAAFWYQKSADLGNANAQFNLADMYFYG DGVGKSLEQSVYWMQKAAEQGYGKAQNQLGVYYRDGIGVAADPIKAYAWFTAAKNNGFEKAASNASDLEK SMNPEDLSKARILGQQYTDNYKAKK |
- |
Nucleotide Sequence: 1128 bp [Download] |
>gi|296105497|ref|NC_014125.1|:c2601412-2600285 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome ATGGACATGAAAAAATATATTTTATCTCTTTCTTTACTGACAGTGCTTAACTCTTCAGCTATCGCTACGA CTCAGGAAGGTGAGGAGGCCTATAACAAAGGGTATTACGAAAAAGCATTTATTTTGTTGTCTCCCGAAGC TGATAAAGGAGATGCCAAAGCTCAATATTTGCTGGGTAAGATGTATTATAATGCCCAAGGTGTAACTTAT AATCCGGAAAAAACAGAGCAATTATTACTTGCCTCAGCGAATCAAGGCAATGTCGATGCCCAGGTGTTGT TAGCGGGTTTCTATTGGTACCTTAATACACCAGATGGCTATAAAAAGGCGTTTGAATGGTATCAGAAAGC AGCTGATCAAAATAATGCAGATGGTCAATATGGCTTGGGCTATATGTATGATACAGGAACTGGCGTACCT CAGAATTCCGATACAGCCATGGTATGGTATAAAAAAGCAGCGGAGCAAGGCAACTCTAATGCGGCTTTGG CTATTGGTTATAATTATGATACCGGAACAGGGGTGAAAAAGGATAAGACTCAAGCTCTCAACTGGTATGC AAAAGCAGCTGACTTAGGTAATGCCAGCGCACAATATAATCTTGGTTTGATGTATGAGCAAGGGGATGGT GTTCCTAAAGATTATCAGAAGGCAGCAGAATATTTCGAGAAAGCAGCGAATCAAGATCATGCCAAATCAC AATTGGAGTTAGGTTATTTATATGACTCTGGAAAATTAGGTAAATCGGATCTGCAAAAGGCCGCTTTTTG GTATCAAAAAAGCGCAGACCTGGGAAATGCTAATGCACAATTTAATTTAGCTGATATGTATTTTTATGGT GATGGGGTCGGAAAAAGCCTTGAGCAATCCGTATACTGGATGCAAAAAGCGGCCGAGCAAGGTTATGGTA AGGCTCAAAATCAATTAGGTGTCTATTACAGAGATGGTATTGGTGTTGCTGCTGATCCTATAAAGGCTTA TGCCTGGTTTACAGCCGCCAAGAATAACGGGTTTGAAAAAGCGGCTAGCAATGCCAGTGATCTTGAGAAA TCTATGAACCCAGAGGATCTGAGTAAGGCGAGAATTTTAGGACAACAATATACGGATAATTATAAGGCTA AAAAATAA |
Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] |
in silico analysis literature |