Effector Protein ID: 296107734 |
T4SS name [ID] | Dot/Icm [43] |
Gene symbol | - |
Locus tag | lpa_03088 |
Strain | Legionella pneumophila 2300/99 Alcoy |
Replicon | chromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 2479856..2485621 [+] |
Product | substrates of the Legionella pneumophila Dot/Icm system SdeB |
Effector type | Protein |
Descripton | SdeB |
T4CP requirement | T4CP Depedent |
Target/Effection | Unknown |
UniProt ID | D5T6N2 |
KEGG ID | lpa:lpa_03088 |
PDB ID | NA |
Domain hit(s) vs Pfam | SidE [PF12252], Evalue: 0, Aligned region: 1..1462 SidE [PF12252], Evalue: 0, Aligned region: 1510..1857 |
Protein Sequence: 1921 a.a. [Download] |
>gi|296107734|ref|YP_003619435.1| substrates of the Legionella pneumophila Dot/Icm system SdeB [Legionella pneumophila 2300/99 Alcoy] MPKYVEGVELTQEGMHAIFARMGHGDITSGSIYNGVPTIDTDALNRQGFMPVLTGVGPRRDSGHWIMLIK GPGNQYFLFDPLGKTSGEGYKNTLLAQLPIASTLSVIPNNPGLNMGLCGYWVASVGLKARAELNKDNPPD LETLGRTTTEEMRNELTDNGYLKITGWLRAVADNFPAGAPQPDAKALRETTEKDLHIELPSPVPPVKDTA PKEVSTKPTAPQIAPKHSLDSKLLENDDDVLDTIKYVHKEYLGKPYPGPLKNPKAPEEGRLPPNEGPDRG PHGLAHTVRTMACAEVMIEEARKAQLRGETLGKAKNGQTLADVTPEELKKILIAQAFFVVGRDDERSGYD DVHKRNFYAEYHEKSEQAFRKYVEDNKLIGKIFKDQKEVDFYAAIILDKNHEWDASPAHILINQGHMVDL MRTKAPAEVALERTYNTLKGTVGSKGAEVVLKAHRDFFFATGAVVPLVNPEAIDDPSRGGPYENPYSGEK FVIVDDKVPASKKDLPKAVNRDYKLKDNERFLTIKEYYAFPDVQQTYPGYKTRLEGSSYYFPTPFAGECE QNPAKCLGAIQKARSKLQTDAIKNGFQSSSDKERRQPNMDEIAAARIIQQIMANPDCIGNDHVSINGQEL GEKFFRDLLAKCDMAVVGSLLNDTDIKNIDTLMRHEKDTEFHSTDPKAVPVRIGDAWENRIRKKGGNVTQ MKQDLIFLMQNDAWYFSRVNAIAQNRDKGSTFKEVLFTALMTPLTNKSLMDTSHVPAPKKLYRGLNLPQE FTNKLINQANAIIANTENTLFTDLSAEAFKQIKLNDFSQMSGRTCASTTKNMKLLTDIWGSNVIFEMLDP DGLLHPKQVGTHMAGSEDEFSVYLPEDVALVPTKVTLDGKTDTEEDRYIFTLVAVKSPDFIPRHESGYAV EPFMKMQKEKVTQALDAIEKDKGGYNIDEQLKNLRIEMVRQAKLPLREGIFDRISHRLSLETSDNKISPE RRDFLNQHVIPVLQECHIALRTNNMEMMQNALAKFPTDKQWSAFKSGEAVRAKAQMDVLKQQIEKKIMLQ TQIIPALTECGEALDKQNVTEALQALNKLPAEKEIGKAKGIGQELRGQIVAVTQELTGNLESLQRAVTTP VVKDAEKMRVRYETLVTDVTKRVTDFEKIKPVNLDSYNKAIADLNNMQQELTLLRNEKIRMHTDKDKAVD FSDIEALEKRLQEAQPNLYPSLVEGTTKGIQELEKIPKSISFDDVKSMTSKINGYLETLEFIRNERVKKH GESTEPLDMSDLDKLKNQLQGVSQHLAQILLNGAKNSLDKIKDPATLEKEGQYIKRCLDHFAELEKTLDS SVKGMKQKEDFNTYKNSLMEKQEKAYPEMLQLQYKSEALITQLRNLCNIHHDNLAKTREEQQQLLNKTGG KLDGFFSQITTAISQAETKKANELARFKTELNNDKNDVSQLIQFLVKKKPSELEENLGISKENAEQLHGL LKQLDAKATPIDKLQENTRLIDEISTKMGSKPVSPEHVAATKAREYYQFLLYGTTQKIGNFEKVKPLDPE SYKKAMSDLNNMQEALQFLRSEKSRIHDDKEKAVEFSDIEALEKRVKNAQPKLLTALLDKTTRDISALVK IPRKLTFEDIKSMTTKHNSYLETLELIRNERIKQHGESPELLDMSDLDSLKGQLQTFNQNLTGMILNATK DGLDRINNRANFNEGEPYVKTCLDLLTELEKTLDSSVKGMKQKEDISACRNSLLDKQEKANSGMLDLQSK SKDLVTQLRDICKIHHGNLAEARRAKLHSLDNQEKGLLGGLWSVTNKLGVTTDTVGIERMQIKMKEQTLR AFKTELTNDKLNTDQIIAFLANKKPSELEEGLGISKENAEELHGLLSKLTSKMTSKIEIEENTQLIDEIS TKIGTEPVQLELTRTVDEDESDTYRRESGYI |
- |
Nucleotide Sequence: 5766 bp [Download] |
>gi|296105497|ref|NC_014125.1|:2479856-2485621 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome ATGCCTAAATACGTAGAAGGGGTAGAATTAACTCAAGAAGGCATGCATGCTATTTTTGCTCGTATGGGGC ATGGCGATATTACCAGCGGTAGCATTTATAATGGAGTACCGACTATTGACACAGATGCCCTGAACAGGCA AGGCTTTATGCCTGTATTAACAGGGGTAGGCCCCAGAAGAGACTCCGGTCACTGGATCATGTTAATCAAA GGACCTGGTAATCAATACTTTCTCTTTGACCCACTAGGTAAAACATCAGGCGAAGGTTATAAAAATACTT TATTAGCCCAATTACCCATAGCATCTACTCTTTCTGTTATTCCCAATAACCCCGGCCTAAACATGGGACT ATGCGGGTATTGGGTTGCCTCTGTCGGGCTAAAAGCTCGTGCTGAACTGAACAAGGACAATCCTCCTGAT TTAGAAACCCTGGGGCGAACCACGACAGAGGAAATGAGAAATGAATTAACCGATAACGGTTATCTGAAAA TTACAGGGTGGTTACGTGCTGTGGCTGATAACTTTCCAGCAGGCGCCCCCCAACCTGATGCGAAAGCTTT AAGAGAAACTACCGAAAAAGATTTACACATAGAGCTCCCCTCCCCTGTTCCTCCAGTGAAAGACACAGCT CCTAAGGAAGTTTCTACAAAACCTACTGCACCACAAATAGCTCCCAAGCATTCTTTGGACAGTAAGTTAT TAGAGAATGACGATGATGTTCTAGACACCATAAAGTATGTTCATAAAGAGTATTTAGGAAAACCATATCC TGGCCCATTAAAAAATCCAAAAGCACCGGAAGAAGGACGACTTCCTCCAAATGAAGGGCCCGATCGAGGA CCTCATGGTCTTGCTCATACGGTAAGAACAATGGCTTGTGCTGAGGTGATGATAGAAGAAGCACGCAAAG CTCAACTGAGAGGAGAGACGTTAGGTAAAGCAAAAAATGGTCAGACTTTAGCTGATGTAACTCCAGAGGA ACTGAAAAAAATTCTCATCGCACAAGCCTTTTTTGTGGTAGGAAGAGATGATGAGCGTTCCGGCTATGAT GACGTACACAAGAGAAATTTCTACGCGGAATATCATGAGAAAAGTGAGCAAGCGTTCAGGAAATACGTTG AAGATAACAAGCTCATCGGCAAAATCTTTAAAGATCAAAAAGAAGTCGATTTCTATGCCGCGATTATTCT GGATAAAAACCATGAATGGGATGCCTCCCCAGCGCATATCCTGATAAATCAAGGCCATATGGTAGACTTA ATGAGAACTAAAGCACCTGCTGAAGTCGCATTGGAACGTACCTACAATACACTGAAAGGTACCGTCGGTT CGAAAGGTGCTGAAGTCGTCCTCAAAGCCCATCGAGATTTTTTCTTTGCTACAGGCGCTGTTGTTCCCTT AGTAAACCCTGAAGCAATTGATGACCCCAGTAGAGGTGGACCTTATGAAAATCCTTATAGCGGGGAGAAA TTTGTTATTGTTGATGATAAGGTACCAGCTTCCAAGAAAGACTTACCAAAAGCTGTAAATCGTGACTATA AACTGAAAGATAACGAACGATTCCTAACCATAAAAGAATACTACGCTTTTCCTGATGTGCAGCAAACCTA CCCTGGTTACAAAACGCGTTTGGAAGGAAGCTCTTACTATTTCCCAACACCATTTGCAGGAGAATGCGAA CAAAACCCTGCAAAATGCCTGGGGGCTATCCAAAAAGCCCGTTCAAAACTACAAACGGATGCCATTAAAA ATGGCTTTCAATCCAGCTCTGATAAAGAGAGAAGACAACCCAATATGGATGAAATTGCGGCCGCCCGCAT CATTCAGCAAATCATGGCCAATCCTGATTGCATAGGTAACGATCATGTGTCCATTAATGGCCAGGAACTG GGGGAAAAATTCTTCCGTGACTTATTAGCGAAATGTGATATGGCTGTTGTAGGCTCGCTGCTCAATGACA CCGACATCAAAAATATCGATACTTTAATGCGACATGAGAAAGACACCGAGTTTCACTCTACCGACCCCAA AGCAGTTCCGGTAAGAATTGGAGACGCCTGGGAGAATAGAATAAGAAAGAAAGGTGGCAACGTCACTCAA ATGAAGCAGGATTTAATTTTCCTCATGCAAAATGACGCCTGGTATTTTAGTCGAGTCAATGCCATCGCAC AAAACCGGGATAAAGGCTCCACTTTCAAAGAAGTGCTGTTTACCGCCTTAATGACGCCTTTGACTAATAA ATCATTAATGGATACATCCCACGTCCCAGCTCCAAAAAAACTGTATCGTGGATTAAATCTGCCACAAGAA TTTACCAATAAATTAATCAATCAAGCCAATGCCATTATTGCCAATACAGAAAATACGCTTTTTACTGATC TCTCAGCTGAAGCCTTCAAACAAATCAAGTTAAATGATTTTAGCCAAATGTCTGGCAGAACCTGTGCCAG TACAACCAAAAATATGAAACTTTTAACCGATATATGGGGCTCCAATGTCATTTTTGAAATGCTTGACCCG GATGGTTTACTGCATCCAAAACAAGTAGGAACTCATATGGCTGGGTCTGAAGATGAATTTTCCGTTTATT TGCCGGAAGATGTCGCTTTAGTTCCAACCAAGGTAACTCTTGATGGAAAAACAGACACAGAAGAAGATCG GTATATCTTTACACTGGTTGCCGTAAAAAGCCCTGACTTTATACCACGTCATGAAAGCGGCTATGCGGTT GAGCCCTTCATGAAAATGCAAAAAGAGAAAGTCACCCAGGCATTGGATGCCATTGAAAAGGATAAAGGCG GCTATAACATCGACGAACAACTAAAAAATCTAAGAATAGAAATGGTACGGCAAGCCAAGTTGCCTCTTAG AGAAGGGATTTTTGATAGAATCTCTCATCGTCTTTCTCTGGAAACCAGTGATAACAAAATATCTCCGGAA CGCAGAGATTTTCTTAACCAACACGTCATCCCTGTCTTACAGGAATGCCATATTGCTCTTAGAACAAACA ATATGGAGATGATGCAAAATGCTTTGGCAAAATTCCCTACCGATAAGCAATGGTCTGCTTTTAAATCAGG AGAAGCGGTTAGGGCCAAAGCTCAAATGGATGTATTAAAGCAGCAGATTGAAAAGAAAATCATGCTGCAA ACTCAAATTATCCCGGCTCTCACGGAATGTGGTGAAGCACTGGATAAACAAAATGTCACAGAAGCATTAC AAGCGCTCAATAAACTGCCTGCAGAAAAGGAAATTGGTAAAGCCAAGGGGATAGGACAAGAATTAAGAGG GCAAATCGTTGCTGTTACACAAGAGCTAACCGGAAATCTTGAATCCCTGCAACGCGCAGTCACTACCCCT GTTGTAAAAGATGCTGAGAAAATGAGAGTACGGTATGAAACCCTTGTCACAGACGTGACAAAACGAGTCA CCGACTTTGAAAAAATCAAACCGGTCAATCTTGACAGTTATAACAAAGCCATTGCCGATTTAAATAACAT GCAACAAGAATTAACTCTTCTGCGCAATGAAAAAATTCGCATGCATACAGATAAAGACAAAGCAGTGGAC TTTTCTGACATAGAAGCCTTGGAAAAGAGATTACAAGAAGCACAACCCAATTTATATCCCTCGCTTGTGG AAGGAACAACAAAAGGTATTCAAGAGCTTGAAAAAATACCCAAGTCAATCAGTTTTGACGATGTTAAATC AATGACATCCAAGATTAATGGTTACCTGGAAACCTTGGAATTCATTCGTAATGAAAGAGTTAAAAAGCAT GGCGAATCCACTGAGCCACTGGATATGTCTGATCTGGATAAATTAAAAAATCAACTACAAGGCGTGAGTC AGCATTTAGCCCAAATTTTATTAAATGGAGCTAAAAACTCACTCGATAAAATCAAGGATCCGGCTACACT CGAAAAAGAAGGACAATATATAAAACGCTGCCTTGACCATTTTGCTGAACTTGAAAAAACTCTGGATAGT TCGGTAAAAGGAATGAAACAAAAAGAAGACTTTAACACCTATAAAAACTCTCTAATGGAGAAGCAGGAGA AAGCCTATCCAGAAATGCTGCAATTGCAATACAAGAGTGAAGCATTGATTACACAATTACGCAATCTATG CAATATTCATCATGATAATTTGGCCAAAACGAGAGAGGAACAACAACAGCTACTGAACAAGACCGGAGGA AAATTAGACGGTTTCTTTAGCCAGATAACGACTGCTATAAGTCAAGCCGAGACAAAGAAAGCAAATGAAC TTGCAAGATTTAAAACTGAATTAAATAATGACAAAAATGATGTGAGTCAACTTATTCAATTTCTGGTAAA GAAAAAACCATCTGAATTGGAAGAAAACTTGGGCATATCGAAAGAGAATGCTGAGCAATTACATGGACTG TTAAAGCAACTAGACGCAAAAGCTACTCCAATAGATAAATTGCAGGAAAACACAAGATTAATTGATGAAA TATCAACCAAAATGGGTAGTAAACCCGTCTCGCCAGAACATGTTGCCGCAACAAAAGCGAGAGAATACTA TCAGTTTCTTCTATATGGAACGACACAAAAAATCGGTAACTTTGAGAAGGTCAAACCTTTGGATCCTGAA AGTTATAAAAAGGCTATGTCCGACTTAAATAACATGCAAGAAGCATTACAATTCCTACGCAGTGAAAAAT CCCGAATACATGATGACAAAGAAAAAGCGGTGGAATTCTCTGATATAGAAGCCTTGGAAAAACGAGTAAA AAATGCTCAACCTAAATTACTGACTGCACTCCTGGATAAAACAACCAGAGATATCTCAGCATTAGTAAAA ATACCCAGGAAATTGACCTTTGAAGATATAAAATCAATGACAACCAAGCATAACAGTTACCTGGAAACCC TGGAATTGATTCGTAATGAAAGAATCAAACAACACGGTGAATCCCCTGAACTTCTGGATATGTCCGATTT GGATAGTTTAAAAGGTCAATTGCAAACCTTTAATCAAAATTTGACTGGCATGATACTAAATGCTACTAAA GATGGTCTGGATAGAATCAATAATAGGGCTAACTTTAATGAAGGAGAACCTTACGTAAAAACATGTCTTG ATCTTTTAACAGAACTTGAAAAAACACTGGATAGTTCGGTAAAAGGAATGAAACAAAAAGAAGACATTAG CGCCTGTAGAAATTCTCTCCTTGATAAACAGGAAAAAGCCAATTCCGGAATGCTGGATTTGCAATCCAAG AGTAAAGATCTAGTTACCCAATTACGTGATATCTGTAAAATTCATCACGGTAATTTAGCTGAAGCAAGAA GAGCCAAGCTTCATTCACTTGATAATCAGGAAAAAGGATTATTAGGTGGATTATGGTCTGTTACTAATAA ATTAGGTGTTACCACAGATACAGTAGGTATCGAGAGAATGCAAATAAAAATGAAGGAACAAACTCTAAGA GCGTTTAAGACAGAGCTTACTAATGACAAGCTTAATACGGATCAAATCATTGCCTTTTTAGCAAATAAAA AACCATCAGAGCTGGAAGAAGGTTTAGGTATATCGAAAGAAAATGCCGAAGAGTTACATGGACTGTTAAG TAAACTCACTAGTAAAATGACTTCGAAAATCGAAATTGAAGAAAATACACAGTTAATTGATGAAATTTCA ACTAAAATAGGCACTGAACCCGTGCAACTCGAATTAACTCGCACTGTAGATGAAGATGAGAGTGATACCT ATCGTCGAGAAAGTGGTTACATTTAG |
Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] |
in silico analysis literature |