SecReT4
Effector Protein ID: 296107734
T4SS name [ID]Dot/Icm [43]
Gene symbol-
Locus taglpa_03088
StrainLegionella pneumophila 2300/99 Alcoy
Repliconchromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon]
Location [Strand]2479856..2485621 [+]
Productsubstrates of the Legionella pneumophila Dot/Icm system SdeB
Effector typeProtein
DescriptonSdeB
T4CP requirementT4CP Depedent
Target/EffectionUnknown
UniProt IDD5T6N2
KEGG IDlpa:lpa_03088
PDB IDNA
Domain hit(s) vs Pfam SidE [PF12252], Evalue: 0, Aligned region: 1..1462
SidE [PF12252], Evalue: 0, Aligned region: 1510..1857
Protein Sequence: 1921 a.a.     [Download]
>gi|296107734|ref|YP_003619435.1| substrates of the Legionella pneumophila Dot/Icm system SdeB [Legionella pneumophila 2300/99 Alcoy]
MPKYVEGVELTQEGMHAIFARMGHGDITSGSIYNGVPTIDTDALNRQGFMPVLTGVGPRRDSGHWIMLIK
GPGNQYFLFDPLGKTSGEGYKNTLLAQLPIASTLSVIPNNPGLNMGLCGYWVASVGLKARAELNKDNPPD
LETLGRTTTEEMRNELTDNGYLKITGWLRAVADNFPAGAPQPDAKALRETTEKDLHIELPSPVPPVKDTA
PKEVSTKPTAPQIAPKHSLDSKLLENDDDVLDTIKYVHKEYLGKPYPGPLKNPKAPEEGRLPPNEGPDRG
PHGLAHTVRTMACAEVMIEEARKAQLRGETLGKAKNGQTLADVTPEELKKILIAQAFFVVGRDDERSGYD
DVHKRNFYAEYHEKSEQAFRKYVEDNKLIGKIFKDQKEVDFYAAIILDKNHEWDASPAHILINQGHMVDL
MRTKAPAEVALERTYNTLKGTVGSKGAEVVLKAHRDFFFATGAVVPLVNPEAIDDPSRGGPYENPYSGEK
FVIVDDKVPASKKDLPKAVNRDYKLKDNERFLTIKEYYAFPDVQQTYPGYKTRLEGSSYYFPTPFAGECE
QNPAKCLGAIQKARSKLQTDAIKNGFQSSSDKERRQPNMDEIAAARIIQQIMANPDCIGNDHVSINGQEL
GEKFFRDLLAKCDMAVVGSLLNDTDIKNIDTLMRHEKDTEFHSTDPKAVPVRIGDAWENRIRKKGGNVTQ
MKQDLIFLMQNDAWYFSRVNAIAQNRDKGSTFKEVLFTALMTPLTNKSLMDTSHVPAPKKLYRGLNLPQE
FTNKLINQANAIIANTENTLFTDLSAEAFKQIKLNDFSQMSGRTCASTTKNMKLLTDIWGSNVIFEMLDP
DGLLHPKQVGTHMAGSEDEFSVYLPEDVALVPTKVTLDGKTDTEEDRYIFTLVAVKSPDFIPRHESGYAV
EPFMKMQKEKVTQALDAIEKDKGGYNIDEQLKNLRIEMVRQAKLPLREGIFDRISHRLSLETSDNKISPE
RRDFLNQHVIPVLQECHIALRTNNMEMMQNALAKFPTDKQWSAFKSGEAVRAKAQMDVLKQQIEKKIMLQ
TQIIPALTECGEALDKQNVTEALQALNKLPAEKEIGKAKGIGQELRGQIVAVTQELTGNLESLQRAVTTP
VVKDAEKMRVRYETLVTDVTKRVTDFEKIKPVNLDSYNKAIADLNNMQQELTLLRNEKIRMHTDKDKAVD
FSDIEALEKRLQEAQPNLYPSLVEGTTKGIQELEKIPKSISFDDVKSMTSKINGYLETLEFIRNERVKKH
GESTEPLDMSDLDKLKNQLQGVSQHLAQILLNGAKNSLDKIKDPATLEKEGQYIKRCLDHFAELEKTLDS
SVKGMKQKEDFNTYKNSLMEKQEKAYPEMLQLQYKSEALITQLRNLCNIHHDNLAKTREEQQQLLNKTGG
KLDGFFSQITTAISQAETKKANELARFKTELNNDKNDVSQLIQFLVKKKPSELEENLGISKENAEQLHGL
LKQLDAKATPIDKLQENTRLIDEISTKMGSKPVSPEHVAATKAREYYQFLLYGTTQKIGNFEKVKPLDPE
SYKKAMSDLNNMQEALQFLRSEKSRIHDDKEKAVEFSDIEALEKRVKNAQPKLLTALLDKTTRDISALVK
IPRKLTFEDIKSMTTKHNSYLETLELIRNERIKQHGESPELLDMSDLDSLKGQLQTFNQNLTGMILNATK
DGLDRINNRANFNEGEPYVKTCLDLLTELEKTLDSSVKGMKQKEDISACRNSLLDKQEKANSGMLDLQSK
SKDLVTQLRDICKIHHGNLAEARRAKLHSLDNQEKGLLGGLWSVTNKLGVTTDTVGIERMQIKMKEQTLR
AFKTELTNDKLNTDQIIAFLANKKPSELEEGLGISKENAEELHGLLSKLTSKMTSKIEIEENTQLIDEIS
TKIGTEPVQLELTRTVDEDESDTYRRESGYI
-
Nucleotide Sequence: 5766 bp     [Download]
>gi|296105497|ref|NC_014125.1|:2479856-2485621 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome
ATGCCTAAATACGTAGAAGGGGTAGAATTAACTCAAGAAGGCATGCATGCTATTTTTGCTCGTATGGGGC
ATGGCGATATTACCAGCGGTAGCATTTATAATGGAGTACCGACTATTGACACAGATGCCCTGAACAGGCA
AGGCTTTATGCCTGTATTAACAGGGGTAGGCCCCAGAAGAGACTCCGGTCACTGGATCATGTTAATCAAA
GGACCTGGTAATCAATACTTTCTCTTTGACCCACTAGGTAAAACATCAGGCGAAGGTTATAAAAATACTT
TATTAGCCCAATTACCCATAGCATCTACTCTTTCTGTTATTCCCAATAACCCCGGCCTAAACATGGGACT
ATGCGGGTATTGGGTTGCCTCTGTCGGGCTAAAAGCTCGTGCTGAACTGAACAAGGACAATCCTCCTGAT
TTAGAAACCCTGGGGCGAACCACGACAGAGGAAATGAGAAATGAATTAACCGATAACGGTTATCTGAAAA
TTACAGGGTGGTTACGTGCTGTGGCTGATAACTTTCCAGCAGGCGCCCCCCAACCTGATGCGAAAGCTTT
AAGAGAAACTACCGAAAAAGATTTACACATAGAGCTCCCCTCCCCTGTTCCTCCAGTGAAAGACACAGCT
CCTAAGGAAGTTTCTACAAAACCTACTGCACCACAAATAGCTCCCAAGCATTCTTTGGACAGTAAGTTAT
TAGAGAATGACGATGATGTTCTAGACACCATAAAGTATGTTCATAAAGAGTATTTAGGAAAACCATATCC
TGGCCCATTAAAAAATCCAAAAGCACCGGAAGAAGGACGACTTCCTCCAAATGAAGGGCCCGATCGAGGA
CCTCATGGTCTTGCTCATACGGTAAGAACAATGGCTTGTGCTGAGGTGATGATAGAAGAAGCACGCAAAG
CTCAACTGAGAGGAGAGACGTTAGGTAAAGCAAAAAATGGTCAGACTTTAGCTGATGTAACTCCAGAGGA
ACTGAAAAAAATTCTCATCGCACAAGCCTTTTTTGTGGTAGGAAGAGATGATGAGCGTTCCGGCTATGAT
GACGTACACAAGAGAAATTTCTACGCGGAATATCATGAGAAAAGTGAGCAAGCGTTCAGGAAATACGTTG
AAGATAACAAGCTCATCGGCAAAATCTTTAAAGATCAAAAAGAAGTCGATTTCTATGCCGCGATTATTCT
GGATAAAAACCATGAATGGGATGCCTCCCCAGCGCATATCCTGATAAATCAAGGCCATATGGTAGACTTA
ATGAGAACTAAAGCACCTGCTGAAGTCGCATTGGAACGTACCTACAATACACTGAAAGGTACCGTCGGTT
CGAAAGGTGCTGAAGTCGTCCTCAAAGCCCATCGAGATTTTTTCTTTGCTACAGGCGCTGTTGTTCCCTT
AGTAAACCCTGAAGCAATTGATGACCCCAGTAGAGGTGGACCTTATGAAAATCCTTATAGCGGGGAGAAA
TTTGTTATTGTTGATGATAAGGTACCAGCTTCCAAGAAAGACTTACCAAAAGCTGTAAATCGTGACTATA
AACTGAAAGATAACGAACGATTCCTAACCATAAAAGAATACTACGCTTTTCCTGATGTGCAGCAAACCTA
CCCTGGTTACAAAACGCGTTTGGAAGGAAGCTCTTACTATTTCCCAACACCATTTGCAGGAGAATGCGAA
CAAAACCCTGCAAAATGCCTGGGGGCTATCCAAAAAGCCCGTTCAAAACTACAAACGGATGCCATTAAAA
ATGGCTTTCAATCCAGCTCTGATAAAGAGAGAAGACAACCCAATATGGATGAAATTGCGGCCGCCCGCAT
CATTCAGCAAATCATGGCCAATCCTGATTGCATAGGTAACGATCATGTGTCCATTAATGGCCAGGAACTG
GGGGAAAAATTCTTCCGTGACTTATTAGCGAAATGTGATATGGCTGTTGTAGGCTCGCTGCTCAATGACA
CCGACATCAAAAATATCGATACTTTAATGCGACATGAGAAAGACACCGAGTTTCACTCTACCGACCCCAA
AGCAGTTCCGGTAAGAATTGGAGACGCCTGGGAGAATAGAATAAGAAAGAAAGGTGGCAACGTCACTCAA
ATGAAGCAGGATTTAATTTTCCTCATGCAAAATGACGCCTGGTATTTTAGTCGAGTCAATGCCATCGCAC
AAAACCGGGATAAAGGCTCCACTTTCAAAGAAGTGCTGTTTACCGCCTTAATGACGCCTTTGACTAATAA
ATCATTAATGGATACATCCCACGTCCCAGCTCCAAAAAAACTGTATCGTGGATTAAATCTGCCACAAGAA
TTTACCAATAAATTAATCAATCAAGCCAATGCCATTATTGCCAATACAGAAAATACGCTTTTTACTGATC
TCTCAGCTGAAGCCTTCAAACAAATCAAGTTAAATGATTTTAGCCAAATGTCTGGCAGAACCTGTGCCAG
TACAACCAAAAATATGAAACTTTTAACCGATATATGGGGCTCCAATGTCATTTTTGAAATGCTTGACCCG
GATGGTTTACTGCATCCAAAACAAGTAGGAACTCATATGGCTGGGTCTGAAGATGAATTTTCCGTTTATT
TGCCGGAAGATGTCGCTTTAGTTCCAACCAAGGTAACTCTTGATGGAAAAACAGACACAGAAGAAGATCG
GTATATCTTTACACTGGTTGCCGTAAAAAGCCCTGACTTTATACCACGTCATGAAAGCGGCTATGCGGTT
GAGCCCTTCATGAAAATGCAAAAAGAGAAAGTCACCCAGGCATTGGATGCCATTGAAAAGGATAAAGGCG
GCTATAACATCGACGAACAACTAAAAAATCTAAGAATAGAAATGGTACGGCAAGCCAAGTTGCCTCTTAG
AGAAGGGATTTTTGATAGAATCTCTCATCGTCTTTCTCTGGAAACCAGTGATAACAAAATATCTCCGGAA
CGCAGAGATTTTCTTAACCAACACGTCATCCCTGTCTTACAGGAATGCCATATTGCTCTTAGAACAAACA
ATATGGAGATGATGCAAAATGCTTTGGCAAAATTCCCTACCGATAAGCAATGGTCTGCTTTTAAATCAGG
AGAAGCGGTTAGGGCCAAAGCTCAAATGGATGTATTAAAGCAGCAGATTGAAAAGAAAATCATGCTGCAA
ACTCAAATTATCCCGGCTCTCACGGAATGTGGTGAAGCACTGGATAAACAAAATGTCACAGAAGCATTAC
AAGCGCTCAATAAACTGCCTGCAGAAAAGGAAATTGGTAAAGCCAAGGGGATAGGACAAGAATTAAGAGG
GCAAATCGTTGCTGTTACACAAGAGCTAACCGGAAATCTTGAATCCCTGCAACGCGCAGTCACTACCCCT
GTTGTAAAAGATGCTGAGAAAATGAGAGTACGGTATGAAACCCTTGTCACAGACGTGACAAAACGAGTCA
CCGACTTTGAAAAAATCAAACCGGTCAATCTTGACAGTTATAACAAAGCCATTGCCGATTTAAATAACAT
GCAACAAGAATTAACTCTTCTGCGCAATGAAAAAATTCGCATGCATACAGATAAAGACAAAGCAGTGGAC
TTTTCTGACATAGAAGCCTTGGAAAAGAGATTACAAGAAGCACAACCCAATTTATATCCCTCGCTTGTGG
AAGGAACAACAAAAGGTATTCAAGAGCTTGAAAAAATACCCAAGTCAATCAGTTTTGACGATGTTAAATC
AATGACATCCAAGATTAATGGTTACCTGGAAACCTTGGAATTCATTCGTAATGAAAGAGTTAAAAAGCAT
GGCGAATCCACTGAGCCACTGGATATGTCTGATCTGGATAAATTAAAAAATCAACTACAAGGCGTGAGTC
AGCATTTAGCCCAAATTTTATTAAATGGAGCTAAAAACTCACTCGATAAAATCAAGGATCCGGCTACACT
CGAAAAAGAAGGACAATATATAAAACGCTGCCTTGACCATTTTGCTGAACTTGAAAAAACTCTGGATAGT
TCGGTAAAAGGAATGAAACAAAAAGAAGACTTTAACACCTATAAAAACTCTCTAATGGAGAAGCAGGAGA
AAGCCTATCCAGAAATGCTGCAATTGCAATACAAGAGTGAAGCATTGATTACACAATTACGCAATCTATG
CAATATTCATCATGATAATTTGGCCAAAACGAGAGAGGAACAACAACAGCTACTGAACAAGACCGGAGGA
AAATTAGACGGTTTCTTTAGCCAGATAACGACTGCTATAAGTCAAGCCGAGACAAAGAAAGCAAATGAAC
TTGCAAGATTTAAAACTGAATTAAATAATGACAAAAATGATGTGAGTCAACTTATTCAATTTCTGGTAAA
GAAAAAACCATCTGAATTGGAAGAAAACTTGGGCATATCGAAAGAGAATGCTGAGCAATTACATGGACTG
TTAAAGCAACTAGACGCAAAAGCTACTCCAATAGATAAATTGCAGGAAAACACAAGATTAATTGATGAAA
TATCAACCAAAATGGGTAGTAAACCCGTCTCGCCAGAACATGTTGCCGCAACAAAAGCGAGAGAATACTA
TCAGTTTCTTCTATATGGAACGACACAAAAAATCGGTAACTTTGAGAAGGTCAAACCTTTGGATCCTGAA
AGTTATAAAAAGGCTATGTCCGACTTAAATAACATGCAAGAAGCATTACAATTCCTACGCAGTGAAAAAT
CCCGAATACATGATGACAAAGAAAAAGCGGTGGAATTCTCTGATATAGAAGCCTTGGAAAAACGAGTAAA
AAATGCTCAACCTAAATTACTGACTGCACTCCTGGATAAAACAACCAGAGATATCTCAGCATTAGTAAAA
ATACCCAGGAAATTGACCTTTGAAGATATAAAATCAATGACAACCAAGCATAACAGTTACCTGGAAACCC
TGGAATTGATTCGTAATGAAAGAATCAAACAACACGGTGAATCCCCTGAACTTCTGGATATGTCCGATTT
GGATAGTTTAAAAGGTCAATTGCAAACCTTTAATCAAAATTTGACTGGCATGATACTAAATGCTACTAAA
GATGGTCTGGATAGAATCAATAATAGGGCTAACTTTAATGAAGGAGAACCTTACGTAAAAACATGTCTTG
ATCTTTTAACAGAACTTGAAAAAACACTGGATAGTTCGGTAAAAGGAATGAAACAAAAAGAAGACATTAG
CGCCTGTAGAAATTCTCTCCTTGATAAACAGGAAAAAGCCAATTCCGGAATGCTGGATTTGCAATCCAAG
AGTAAAGATCTAGTTACCCAATTACGTGATATCTGTAAAATTCATCACGGTAATTTAGCTGAAGCAAGAA
GAGCCAAGCTTCATTCACTTGATAATCAGGAAAAAGGATTATTAGGTGGATTATGGTCTGTTACTAATAA
ATTAGGTGTTACCACAGATACAGTAGGTATCGAGAGAATGCAAATAAAAATGAAGGAACAAACTCTAAGA
GCGTTTAAGACAGAGCTTACTAATGACAAGCTTAATACGGATCAAATCATTGCCTTTTTAGCAAATAAAA
AACCATCAGAGCTGGAAGAAGGTTTAGGTATATCGAAAGAAAATGCCGAAGAGTTACATGGACTGTTAAG
TAAACTCACTAGTAAAATGACTTCGAAAATCGAAATTGAAGAAAATACACAGTTAATTGATGAAATTTCA
ACTAAAATAGGCACTGAACCCGTGCAACTCGAATTAACTCGCACTGTAGATGAAGATGAGAGTGATACCT
ATCGTCGAGAAAGTGGTTACATTTAG

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature