| Effector Protein ID: 296107698 |
 T4SS name [ID] | Dot/Icm [43] |
| Gene symbol | - |
| Locus tag | lpa_03037 |
| Strain | Legionella pneumophila 2300/99 Alcoy |
| Replicon | chromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2429099..2433565 [-] |
| Product | Sid -like protein |
| Effector type | Protein |
| Descripton | LaiA/SdeA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | An integrin-like protein involved in adhesion to and invasion of human lung alveolar epithelial cells. (Chang et al. 2005) |
| UniProt ID | D5T661 |
| KEGG ID | lpa:lpa_03037 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | SidE [PF12252], Evalue: 0, Aligned region: 1..1428 |
| Protein Sequence: 1488 a.a. [Download] |
| >gi|296107698|ref|YP_003619399.1| Sid -like protein [Legionella pneumophila 2300/99 Alcoy] MPRYVEGVELTQEGMDAIFTRMGHSDIISGIIYNEQPTIDQEALNKQGFMPVLAGVGSRSDSGHWLMLIK GPGKQYYLFDPLGKTSGEGYQNTLLAQLPGGSNLSVIPNGPDLNKGLCGYWVASVGLRAHAQLNTDSPPD LVNLGQTITNEMRNELEHDGYRIITDWLRAVADEFPEGDPQPDARALREFTQKALGINIPPPVPPMKDLT PKELPVESNCFQLPYVPVWNGFSLYTDDIVRAAAQYAYDNYLGKRYTGTVESVPANFGGQMVYRQHHGLS HTLRTMAYAELIVEEARKAKLRGETLRKFKDGRTIADVTPEELKKIMVAQAFFVAGRDDEASDAENYRKY HEQSRDAFLKYVKDNESTLIPDVFKDEEDVNLYAQVIEDKNHDWSSSPAIVLINQAHMVDLVRVKQPPES YLENYFKSMLPWIGPQATEAVFAIQRQFFHATHEVVAGFDSDNKEPHLVVAGLRRYVIGEDGQPIREAPK KGQKEGDLKAFPQAYQLKGNERFMRVDEFLKLPEVQSTFPGSGKHLEGGMPGMSYMDYWNRLNSRERARC ENDVDFCLKQLEIAHHKAKIDPIKVAVQPSEKITRREPNIDEIAAAGIIREILANPDSIQNDHVLINGQK LEEQFFRDLLAKCEMAVVGSLLNDTDIGNIDALMRHERDTEFHSTGEEAIPKKIGAKWEKKQNKYNASRN ITETKHNLIFLMQDDSWYFSRVNAIAQNRDKGSTFNEVLITTLMTPVTSKALVDTSRAPAPKRLFRGLNF SEEYAQGLINQANTMIANTTERLFTDHSPEAFKQIKLNDLSKMSGRTNASTTTNIELCRTIWDSNVIFEM LDPDGLLQPKQVGQHGAGTESEFSVYLPEDVALVPVKVTLDESKTENGGNRYIFTFVAVKSPDFIPRHES GYAVEPFLRMQTAKLAEIKSSVKNNQVAPIIELQSDLSLVEVTDLPSAYKDFIKNTVVPVLENCLNVFLN KDAVALSKALAAFPPDGQWSVFNSPEAMHAKRQMDALKQMVPNKVVFDTLAQCQDALEKQNIAGALEAFK NIPSEKEMGTISRELREQIQSTRQELESLQRAVVTPVITDEKKVRERYDALIEGTSKKVTELEKATLDKL DVIKKAISNLGNLRQEVTLLHNEKVRMHSKTDTIDFSDIEKLEQQIQVMDTKLADAYLLAVTKQISALES IPKDQSELKAKIATFFDTITEIEMLRNERIKKYGASKDPHDLSDLDKLSGNLQGVNQSLVSNLIKTIRSS CIQMKSNTFQMQKEAIEENIELLEKLEKSMDKSETAEKLRKDIPKLKDLLIAQQKAYPKMTQLIEQLREL CQTHHDDLNKKRTARLQELDRQAAEGGITGIVGNIFFGVTNMIGLTKDEQLEIKMKQQSLARFKADLFDE KNDIDALLVKLAYKSPSDLQEGLGISENNAKELDSLIRNLVAKTYSANELEEKLKAIDKISPKLARECKS LKFEAIGNDESTGNTMRF |
| - |
| Nucleotide Sequence: 4467 bp [Download] |
| >gi|296105497|ref|NC_014125.1|:c2433565-2429099 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome ATGCCTAGATATGTCGAAGGGGTAGAATTAACTCAAGAAGGTATGGACGCTATTTTCACCCGTATGGGGC ATAGCGATATTATTAGCGGTATTATATACAATGAGCAGCCGACTATTGATCAAGAAGCTCTCAACAAGCA GGGTTTTATGCCGGTGTTAGCAGGGGTAGGCTCCAGAAGTGATTCCGGTCACTGGCTCATGTTAATCAAA GGACCTGGTAAACAATATTATCTCTTTGACCCATTGGGTAAAACTTCCGGTGAAGGTTATCAAAATACGT TATTAGCCCAATTACCTGGAGGTTCTAATCTCTCTGTCATACCAAATGGCCCTGATTTAAACAAGGGATT ATGCGGCTATTGGGTTGCTTCAGTTGGTTTAAGAGCGCATGCTCAATTAAACACAGATAGTCCCCCTGAT TTAGTGAATCTGGGGCAAACCATCACCAATGAAATGCGCAATGAACTGGAACATGACGGTTATAGAATAA TTACTGACTGGCTAAGAGCTGTAGCAGATGAATTTCCGGAAGGTGATCCCCAACCTGATGCGAGAGCATT AAGAGAGTTTACACAAAAAGCTCTTGGTATCAATATACCCCCTCCTGTTCCTCCGATGAAAGATCTAACT CCCAAAGAGCTCCCTGTTGAATCTAATTGCTTTCAACTGCCATACGTGCCAGTTTGGAATGGGTTTTCAT TGTATACCGATGACATCGTTCGAGCTGCGGCACAATACGCCTATGACAATTATCTGGGCAAACGTTATAC CGGGACAGTTGAATCAGTACCGGCAAATTTTGGTGGGCAAATGGTGTATAGACAACACCATGGGCTTTCC CATACTTTACGGACCATGGCTTATGCAGAATTGATTGTTGAAGAAGCACGTAAAGCCAAATTACGAGGGG AAACATTAAGAAAATTCAAAGATGGTCGTACTATTGCTGACGTTACCCCTGAAGAACTGAAAAAAATCAT GGTTGCCCAGGCATTTTTTGTAGCTGGGCGTGATGATGAAGCATCCGATGCCGAGAACTATAGAAAGTAT CATGAACAAAGCCGTGATGCTTTCTTAAAGTATGTGAAAGACAATGAGTCCACACTAATTCCTGATGTCT TCAAAGATGAGGAGGATGTCAATTTGTATGCCCAAGTGATTGAAGATAAAAATCATGATTGGAGTTCAAG TCCGGCCATTGTTTTGATTAACCAGGCACACATGGTCGATTTGGTCCGGGTGAAACAACCCCCTGAGTCT TATTTGGAAAATTATTTCAAGTCCATGCTGCCTTGGATAGGCCCCCAGGCCACTGAAGCTGTTTTTGCCA TACAAAGACAATTTTTTCATGCTACTCATGAAGTGGTGGCGGGTTTTGACTCCGACAACAAAGAGCCTCA TTTGGTTGTTGCTGGTTTACGTCGTTATGTCATCGGTGAGGATGGGCAACCCATCAGAGAGGCACCTAAA AAAGGACAAAAAGAAGGTGATTTAAAAGCTTTTCCTCAAGCTTATCAACTGAAAGGAAATGAACGCTTTA TGCGAGTCGATGAGTTTTTAAAACTTCCTGAAGTCCAAAGTACTTTCCCTGGTTCTGGTAAACATTTGGA AGGCGGAATGCCCGGGATGAGTTACATGGATTACTGGAATAGACTGAATTCCAGAGAAAGAGCACGATGT GAAAACGATGTCGATTTTTGTTTAAAACAATTAGAAATCGCCCATCACAAAGCCAAAATTGATCCTATAA AGGTTGCTGTTCAACCGAGCGAAAAAATAACGAGGAGAGAACCTAATATCGATGAGATAGCTGCGGCTGG CATTATTAGAGAAATACTCGCCAATCCTGATTCCATTCAGAATGATCATGTGCTCATTAATGGCCAAAAA CTGGAAGAACAATTTTTCCGCGATTTGTTAGCCAAATGCGAGATGGCTGTTGTAGGCTCACTGCTTAATG ACACCGACATAGGAAACATCGATGCTTTAATGCGGCATGAGAGAGACACCGAGTTTCATTCTACTGGTGA AGAAGCAATTCCAAAAAAAATTGGAGCTAAATGGGAAAAGAAACAAAATAAATATAATGCTAGTCGCAAC ATCACCGAAACGAAACACAATTTAATTTTCCTCATGCAAGATGATTCCTGGTACTTTAGCCGAGTCAATG CCATCGCACAAAATAGGGATAAAGGCTCCACTTTCAACGAAGTGCTGATTACCACTTTAATGACGCCTGT AACTAGTAAAGCACTAGTGGATACATCACGCGCCCCTGCTCCGAAAAGACTGTTTCGTGGATTAAATTTT TCAGAAGAATATGCTCAGGGATTAATCAATCAAGCCAATACAATGATCGCCAATACGACAGAGCGTCTAT TTACAGATCATTCACCAGAAGCCTTTAAACAAATCAAGTTAAATGATTTAAGTAAAATGTCCGGCAGAAC TAATGCCAGTACAACCACGAATATCGAACTGTGTAGAACAATCTGGGACTCCAATGTCATCTTTGAAATG CTTGACCCGGATGGTTTGCTGCAGCCTAAGCAAGTTGGGCAACATGGGGCGGGCACTGAAAGTGAATTCT CCGTTTATTTGCCAGAGGATGTTGCACTGGTCCCAGTCAAAGTGACCCTTGATGAAAGTAAAACGGAAAA TGGAGGAAATCGGTATATCTTTACCTTTGTTGCCGTAAAAAGTCCTGACTTTATACCTCGCCATGAAAGC GGCTATGCGGTTGAACCGTTTTTAAGAATGCAAACTGCCAAGTTAGCCGAAATCAAAAGCTCTGTTAAAA ATAACCAGGTAGCGCCAATTATCGAATTACAAAGCGATTTAAGCCTAGTGGAAGTGACAGATTTACCCTC TGCATATAAAGATTTTATAAAAAATACAGTCGTCCCAGTTTTGGAAAATTGTCTTAATGTATTCTTGAAC AAGGATGCGGTCGCTTTAAGTAAAGCCTTAGCGGCATTTCCACCCGACGGACAATGGTCAGTTTTCAACT CTCCAGAAGCAATGCATGCCAAAAGACAGATGGATGCTCTTAAACAAATGGTTCCAAATAAAGTAGTGTT CGACACCTTGGCTCAATGCCAGGACGCGCTGGAAAAACAAAATATCGCTGGCGCACTGGAGGCATTCAAA AACATCCCATCTGAAAAAGAGATGGGTACCATTAGCAGAGAGCTAAGAGAACAAATCCAGAGCACCAGGC AAGAACTGGAATCATTGCAACGTGCTGTCGTTACCCCGGTAATTACAGATGAAAAGAAAGTAAGAGAACG CTATGATGCCCTGATCGAAGGCACATCGAAGAAAGTTACTGAACTTGAAAAAGCAACACTTGACAAACTT GATGTCATTAAGAAGGCAATTTCTAATTTAGGTAACCTTAGACAAGAAGTGACGCTGTTGCATAATGAAA AAGTACGGATGCACAGTAAAACTGATACAATTGATTTTTCAGATATTGAAAAACTGGAACAACAAATACA GGTCATGGATACCAAATTAGCCGATGCTTATTTACTTGCAGTAACCAAGCAAATTTCAGCTCTTGAAAGC ATACCTAAAGATCAGTCTGAATTGAAAGCAAAAATAGCTACATTTTTTGATACAATTACCGAGATTGAGA TGTTGCGTAATGAGCGAATCAAGAAATACGGTGCATCGAAAGATCCGCACGATCTGTCTGATTTGGATAA ATTAAGCGGCAACTTACAAGGTGTTAATCAATCTCTGGTTTCGAATCTGATAAAAACTATCCGGAGCTCT TGCATTCAAATGAAATCTAATACTTTTCAAATGCAAAAAGAGGCAATAGAAGAGAATATCGAGTTACTCG AAAAGCTTGAAAAATCAATGGATAAATCAGAAACAGCAGAAAAACTGAGGAAGGATATTCCTAAACTAAA GGATTTGCTGATTGCACAACAAAAGGCCTATCCTAAAATGACACAATTGATTGAGCAATTACGCGAGCTA TGTCAAACCCACCATGATGATTTAAATAAAAAAAGAACGGCGAGATTGCAAGAATTGGATAGACAGGCCG CAGAAGGTGGGATAACTGGAATAGTAGGAAATATATTCTTTGGGGTTACCAACATGATCGGTTTAACCAA AGATGAGCAACTCGAAATTAAAATGAAGCAGCAATCGCTTGCGCGCTTCAAAGCTGACTTGTTTGACGAG AAAAATGATATTGATGCTCTTCTAGTGAAGTTGGCATATAAAAGTCCATCTGACCTGCAAGAAGGGTTAG GGATATCTGAAAACAATGCCAAGGAGTTGGATTCACTTATAAGGAATTTGGTGGCGAAAACTTATTCTGC AAATGAATTGGAAGAGAAATTGAAAGCTATTGATAAGATCTCCCCAAAACTAGCCAGAGAGTGCAAAAGT TTGAAATTTGAAGCGATTGGCAATGACGAGTCTACTGGAAATACAATGAGATTCTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |