| Effector Protein ID: 296107591 |
 T4SS name [ID] | Dot/Icm [43] |
| Gene symbol | - |
| Locus tag | lpa_02889 |
| Strain | Legionella pneumophila 2300/99 Alcoy |
| Replicon | chromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2319234..2320676 [+] |
| Product | UVB-resistance protein UVR8 |
| Effector type | Protein |
| Descripton | PieG/legG1 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | LegG1 has an RCC1 domain which can act as a guanine-nucleotide dissociation stimulator for the Ran GTP-binding protein (de Felipe, et al. 2005) |
| UniProt ID | D5TEQ6 |
| KEGG ID | lpa:lpa_02889 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | RCC1 [PF00415], Evalue: 2.8e-27, Aligned region: 255..297 RCC1 [PF00415], Evalue: 2.8e-27, Aligned region: 312..357 RCC1 [PF00415], Evalue: 2.8e-27, Aligned region: 369..413 |
| Protein Sequence: 480 a.a. [Download] |
| >gi|296107591|ref|YP_003619292.1| UVB-resistance protein UVR8 [Legionella pneumophila 2300/99 Alcoy] MPDASGKPDANQIPDDVWLDILINYLQPQDAVNLSEVNNRLNRLFATQHTQSEQLHRKKILGILKVFTGY SSTFLFIRFNGKQRLFKTRNWSAVDSDNITPLLMPISLPENISFIESIQSTYKHTVVVGRDNRDQIIVAT NKIHKDYAQQETSHTQLIPLPLRNNNISLVSVGNNEESYIFNPIFLLSRNAAGQLSLQLHKINSKAPLET TIEERDCQFPIPLPDTLKTVTKINSGIWHTVIAGYDQYNRPQLATFGKNCDGQLGTGDCENRDTPTLAKL PPEMHTLHIIQTGFFHTIIAGLDKNGCPIIASCGYNSDGQLGCGDKDNKNTLIPIKLPENMKSVEMVATG VKHTVIVGKDINNKPVVATCGHNGYGQLGTGDEENRLCLTPIEIPEDITTVDYVGAGTYHTVICGRNMKN QPILALCGCNSDGELGLAPQKIAKKSSLMTNPALFFPPRQDRNAINNVMKISKFSPCNLL |
| - |
| Nucleotide Sequence: 1443 bp [Download] |
| >gi|296105497|ref|NC_014125.1|:2319234-2320676 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome ATGCCTGATGCTAGCGGCAAACCTGATGCAAACCAGATTCCAGATGACGTCTGGCTTGACATTCTTATCA ATTATCTTCAACCACAGGATGCTGTGAACCTGTCTGAAGTCAACAATCGCCTGAACCGACTTTTCGCAAC TCAACATACTCAATCTGAGCAATTGCACCGAAAAAAAATATTAGGAATTCTGAAGGTATTTACAGGATAT AGTTCCACCTTCCTGTTTATACGCTTCAATGGCAAACAAAGATTATTTAAAACAAGAAACTGGAGTGCAG TGGATAGCGATAACATAACCCCACTATTAATGCCCATCTCTCTGCCAGAGAACATCTCTTTTATTGAATC CATTCAATCAACATACAAACACACTGTTGTTGTTGGTCGTGATAATCGCGATCAAATTATAGTGGCAACA AATAAAATCCATAAGGATTATGCACAGCAAGAAACCAGCCATACTCAGCTGATTCCCCTTCCATTACGCA ATAATAACATTTCTCTGGTATCTGTCGGGAATAATGAAGAGAGTTATATTTTTAACCCTATTTTTCTCTT ATCCCGCAATGCAGCAGGGCAATTGAGTCTTCAATTACATAAAATAAATAGCAAGGCTCCATTGGAAACC ACAATTGAGGAAAGAGACTGCCAGTTTCCCATTCCATTGCCTGACACGCTTAAGACAGTAACAAAAATAA ATTCAGGGATATGGCATACCGTCATTGCGGGCTATGATCAATATAACCGACCTCAACTCGCCACCTTTGG AAAAAACTGCGATGGTCAATTAGGTACTGGGGATTGCGAAAACCGAGATACGCCCACCCTGGCAAAGCTT CCCCCTGAAATGCATACGCTTCATATAATCCAAACCGGATTTTTTCACACCATTATCGCTGGGCTTGATA AAAATGGATGCCCTATCATTGCAAGCTGCGGTTATAACTCCGATGGCCAATTGGGATGCGGGGATAAAGA TAATAAAAACACATTGATTCCCATCAAACTTCCAGAAAATATGAAATCAGTAGAAATGGTCGCCACTGGA GTAAAGCACACCGTTATTGTGGGAAAAGACATAAATAACAAGCCTGTGGTTGCAACCTGTGGGCATAACG GTTATGGGCAGCTGGGTACAGGCGATGAAGAGAACCGACTCTGCTTAACTCCCATCGAGATTCCCGAGGA CATTACAACTGTCGATTATGTTGGAGCAGGCACCTATCATACAGTCATTTGTGGACGGAACATGAAAAAT CAGCCGATTCTTGCTTTATGTGGGTGCAACTCAGACGGTGAATTGGGACTTGCTCCACAAAAAATCGCCA AAAAATCATCCCTGATGACCAACCCGGCCCTGTTCTTTCCACCGAGACAAGACAGGAACGCAATAAACAA TGTGATGAAAATTAGTAAATTCTCGCCATGTAATTTGCTATGA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |