| Effector Protein ID: 296107575 |
 T4SS name [ID] | Dot/Icm [43] |
| Gene symbol | - |
| Locus tag | lpa_02863 |
| Strain | Legionella pneumophila 2300/99 Alcoy |
| Replicon | chromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2299658..2301367 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | PieA/lirC |
| T4CP requirement | T4CP Depedent |
| Target/Effection | PieA is recruited to the cytoplasmic face of the LCV and overexpression alters lysosome morphology through an unknown mechanism. (Ge and Shao, 2011) |
| UniProt ID | D5TEP0 |
| KEGG ID | lpa:lpa_02863 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 569 a.a. [Download] |
| >gi|296107575|ref|YP_003619276.1| hypothetical protein lpa_02863 [Legionella pneumophila 2300/99 Alcoy] MQEKIINLGKGLKKVNEGIKKHISRAEEFLYLANQWEKENVKINDLLDGVQFSVNDKKMSGQEIKEELSN LIERYNNFLKKNLKGERSETLELKEIQQQLINFYNAVNDIYTYLSINKTEFFLEAIKSCYKKDQRMSSTI QFVLKIADHLSKERLQFNLNLNSQFTEASESFQEVTTKFYREVATPRMESANKLLELMNNFVDQYISQGA SPEDVIKKLKPFEKYFVIEISHYEEFGHLVYKTNFNCNPALFDVNPIEFLNELFVQFYKDTTLSSRSKAA LKKVLDKFEVTYEVPKTWYSYIDWDIPIVTDKNSVLVTYDKQAYNKYHQESGQREMEFFETIERCLDKSK DIIIATKKENLKDQKEFCKLIDKAIKELEETKKKKIFQKEPHELVTSIINKSIKLLHDLKNNMPLRREDL VIVILSTENALTAAKSKLRPQEINLSEPIKCIKNFKKTLSIKQKEELCFYKSDEEKSIFSKYINSELREL VESYKVQKPCEKELVNEPEKNNSPQTIESKEEDKKIDLNKKMNLYRVQKIMKSFVFEYSGYKGGKKVKEG GGNDRRTEK |
| - |
| Nucleotide Sequence: 1710 bp [Download] |
| >gi|296105497|ref|NC_014125.1|:c2301367-2299658 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome ATGCAAGAAAAAATTATCAACTTAGGGAAGGGGCTTAAAAAGGTCAATGAAGGTATTAAAAAACATATTT CTCGAGCAGAAGAGTTCCTCTACTTGGCGAACCAATGGGAAAAAGAGAATGTTAAGATTAATGATTTATT GGATGGAGTGCAGTTTTCAGTTAATGATAAAAAAATGTCGGGTCAAGAAATTAAAGAAGAACTATCTAAT CTAATAGAAAGATATAATAATTTCCTAAAAAAAAACTTAAAAGGGGAAAGAAGTGAAACATTAGAACTAA AGGAGATTCAGCAACAACTTATCAATTTTTATAATGCTGTTAATGATATTTATACTTATTTATCCATAAA TAAAACAGAGTTTTTTCTTGAAGCAATCAAGTCTTGCTACAAAAAAGATCAGAGGATGAGTAGTACAATT CAGTTTGTGCTGAAGATAGCGGATCATCTTTCTAAGGAGAGACTACAATTTAATTTGAATTTAAATTCGC AATTTACAGAAGCTTCAGAGAGTTTTCAAGAGGTAACTACCAAATTTTACAGAGAAGTTGCTACTCCTAG AATGGAGTCTGCAAACAAATTGTTAGAGCTGATGAATAATTTCGTAGACCAATATATATCACAAGGGGCA AGTCCAGAAGATGTAATAAAAAAACTTAAGCCATTTGAGAAATATTTTGTTATTGAAATTTCGCATTATG AAGAGTTTGGGCATTTAGTATATAAAACAAACTTTAATTGTAATCCAGCGTTATTTGATGTTAATCCTAT CGAATTTTTAAATGAATTATTCGTGCAATTTTATAAAGACACCACTTTATCATCTCGCTCTAAAGCTGCT TTAAAAAAAGTGCTTGATAAATTTGAGGTTACTTATGAGGTGCCAAAGACCTGGTATAGTTATATTGATT GGGATATTCCTATTGTAACTGATAAAAATTCAGTATTAGTTACTTATGACAAACAAGCTTATAACAAATA TCATCAAGAAAGCGGCCAGAGAGAAATGGAGTTTTTCGAGACAATTGAACGATGTTTGGATAAGTCGAAA GACATTATCATTGCGACTAAAAAGGAAAATTTAAAAGACCAAAAAGAATTTTGTAAATTGATAGATAAAG CTATTAAGGAATTAGAAGAAACAAAAAAGAAAAAAATTTTTCAAAAGGAGCCGCATGAGCTGGTAACAAG TATTATCAATAAATCAATAAAGTTGTTACACGACTTGAAAAATAATATGCCATTAAGACGAGAAGATTTG GTCATAGTAATCTTAAGTACGGAAAACGCTTTAACTGCAGCAAAATCAAAATTAAGGCCACAAGAAATCA ATTTATCCGAACCGATAAAATGCATTAAAAATTTTAAAAAGACATTATCAATAAAACAAAAAGAAGAGCT CTGCTTTTATAAATCAGATGAAGAAAAATCTATTTTCTCCAAATACATAAACTCTGAGCTTAGAGAACTT GTCGAATCTTACAAGGTTCAAAAGCCATGCGAAAAAGAGTTGGTTAATGAGCCAGAAAAAAATAATTCAC CACAGACAATAGAATCAAAAGAAGAGGATAAAAAAATTGATTTAAATAAGAAAATGAATTTATACCGTGT TCAAAAAATTATGAAAAGTTTTGTATTCGAGTATAGCGGGTATAAAGGAGGAAAAAAAGTAAAAGAAGGG GGGGGCAACGATAGAAGAACTGAAAAATAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |