SecReT4
Effector Protein ID: 296107067
T4SS name [ID]Dot/Icm [43]
Gene symbol-
Locus taglpa_02168
StrainLegionella pneumophila 2300/99 Alcoy
Repliconchromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon]
Location [Strand]1703562..1706087 [+]
Producthypothetical protein
Effector typeProtein
DescriptonLgt3/legc5
T4CP requirementT4CP Depedent
Target/EffectionLgt3 is important for initiation of infection cycle (Belyi, et al. 2011)
UniProt IDD5TD81
KEGG IDlpa:lpa_02168
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 841 a.a.     [Download]
>gi|296107067|ref|YP_003618767.1| hypothetical protein lpa_02168 [Legionella pneumophila 2300/99 Alcoy]
MKEQQKAIFIENIKSTCAVDEQMAKELADSLLEIHQLNTGVNEQTLINEVFLTKFALYLKIGKEVALDWV
RKNKDLDTPFPSDAVENQPAKDAKKPVENKAQVYGAMTVGRSPVNKALNQLTNDLLKEVVERGKTQKAQK
LRAYIFDQLARRLEASLSQEQINDLYNRIRGTGDYTKSESFSEEQLKILKEKVVPELKRELSDLSNGNVN
ILGLDVSREDKYAFDTTNIFSVWFSNNPAVYMPQHVKTQVEKTAKLNQPGKTRIVFSSLCLNETAQIDFQ
QWAKENNIELVDIDSIDLKSVSETDAQLLNLAKDELEAMRKGKGGNPAAASDLVRWVDVIIGESSTYIDI
DLPMNDKKVTVEVHSGFPVLLNMGSALTKDGQQPAMENPAFNTDMIAYSKDKEARRQIIEGVAKKIIARY
ENCAKYIEESKNEELVRLKNSPGYKLFIEKTDGKFDLCALRAAVSEAHQDALSFATFFGAEYFAKTFATQ
ELIPVIKEAIQHQNQDLLTSVIENHIEKQHLNDYPKTPDGIKKLLKSFQGIVYKPLVMEFSGPSAVSSSW
VEAISGRSIPRNFEYLAEPMSQPLRVLQHHACVSGKANFSSDNIPKWCELQSDVEKRQQQREDGLSWLPD
AQEKLKREGQQAKLEEEQRIKLEEEQRIKLEEEQRIKLEEEQRIKLEEEQQIKLEEEQQIKLEEEHKSKK
YFAQSDAIDLILNNFENEINSIGAYYAPAKQRAIELLDTLRKYKEEAFNDPSREKLISFAQNTKRAIQEA
TPILQKDLGWGDYLTNLAKQLVNAVTFAVAYAVTFGTTGHQGFFALKSSLAVSQSQNLVEALNSELSQKN
C
-
Nucleotide Sequence: 2526 bp     [Download]
>gi|296105497|ref|NC_014125.1|:1703562-1706087 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome
ATGAAAGAGCAACAAAAGGCAATTTTTATTGAGAATATCAAATCGACATGCGCTGTTGACGAGCAAATGG
CTAAAGAATTGGCTGATTCATTGCTTGAAATTCACCAGTTAAACACTGGAGTTAATGAACAAACACTGAT
TAATGAGGTGTTTTTAACTAAATTTGCCCTTTATCTTAAAATTGGGAAAGAGGTTGCCTTAGATTGGGTT
CGAAAAAATAAGGACTTGGATACTCCGTTTCCTTCTGATGCAGTCGAAAATCAGCCTGCTAAGGATGCGA
AAAAGCCTGTTGAGAACAAGGCTCAAGTATATGGAGCTATGACAGTTGGACGCTCTCCTGTTAATAAGGC
TTTAAATCAACTAACCAATGATCTTTTGAAAGAGGTCGTTGAACGTGGAAAGACTCAGAAAGCTCAAAAA
TTACGAGCTTATATATTCGACCAACTGGCAAGGCGATTAGAAGCTTCGCTTAGCCAAGAGCAGATTAACG
ATTTATATAACAGAATAAGAGGCACTGGCGACTATACTAAAAGCGAATCATTTTCCGAAGAACAACTTAA
AATTTTAAAAGAAAAAGTTGTTCCAGAATTAAAGAGAGAGCTAAGTGACCTCAGCAACGGGAATGTTAAT
ATCCTGGGGTTGGACGTTAGTCGTGAAGATAAATACGCATTTGATACAACCAATATATTTTCTGTCTGGT
TTAGCAATAACCCAGCAGTTTACATGCCACAACATGTTAAAACTCAAGTAGAAAAAACTGCAAAACTTAA
CCAGCCAGGCAAAACTCGAATTGTTTTTAGCTCATTATGCTTGAATGAGACAGCACAGATTGATTTTCAG
CAATGGGCAAAGGAAAATAACATTGAATTGGTTGATATAGATTCAATAGATTTAAAATCGGTCAGTGAAA
CGGATGCTCAATTGCTAAATCTAGCCAAAGATGAGCTTGAAGCAATGAGAAAGGGCAAGGGAGGAAATCC
TGCTGCAGCATCCGATCTGGTGCGTTGGGTTGATGTAATCATTGGAGAAAGCAGTACTTATATTGATATT
GATTTACCAATGAATGATAAAAAAGTCACTGTTGAGGTTCATTCTGGTTTCCCAGTTCTACTTAATATGG
GGTCAGCGCTCACAAAGGATGGCCAACAACCTGCTATGGAAAACCCGGCTTTCAATACTGATATGATTGC
TTATAGCAAAGATAAAGAGGCACGTCGTCAAATAATCGAGGGGGTTGCCAAAAAGATCATTGCGCGTTAT
GAAAACTGCGCGAAATATATTGAGGAAAGCAAAAACGAAGAGTTAGTACGTTTAAAAAATTCGCCAGGTT
ATAAATTATTTATTGAAAAAACAGATGGCAAATTTGATTTATGTGCTTTAAGGGCGGCGGTTTCAGAAGC
TCACCAGGATGCTTTGTCGTTTGCAACTTTTTTTGGCGCTGAGTATTTTGCTAAAACTTTTGCTACACAA
GAACTTATACCTGTAATTAAAGAGGCAATTCAGCATCAAAATCAAGATTTGCTTACATCTGTTATTGAAA
ATCATATAGAAAAACAACATCTCAATGACTATCCCAAGACTCCCGATGGCATTAAAAAACTATTGAAGTC
GTTTCAAGGGATTGTCTATAAACCATTGGTTATGGAATTCTCAGGCCCAAGTGCCGTCTCATCATCTTGG
GTGGAAGCTATATCTGGAAGATCCATCCCGAGGAATTTTGAATATTTAGCTGAACCTATGTCTCAACCAT
TACGAGTTTTACAGCATCATGCCTGTGTATCTGGAAAAGCTAATTTTTCTTCTGATAACATTCCTAAATG
GTGTGAACTTCAGTCTGATGTAGAAAAACGACAACAACAAAGAGAAGATGGACTTTCCTGGCTTCCTGAT
GCTCAAGAGAAGCTTAAGAGGGAAGGGCAGCAAGCCAAACTTGAGGAAGAACAACGAATCAAGCTTGAAG
AGGAACAACGAATCAAGCTTGAAGAAGAACAACGAATCAAGCTTGAGGAAGAACAACGAATCAAACTTGA
GGAAGAGCAACAAATCAAACTTGAGGAAGAGCAACAAATCAAACTTGAGGAAGAGCACAAAAGCAAAAAA
TACTTTGCTCAGTCCGATGCTATTGATCTCATTTTGAATAATTTTGAAAATGAAATTAACTCTATTGGTG
CTTATTATGCCCCTGCAAAACAAAGAGCTATAGAGTTGCTAGATACTTTGAGAAAATATAAAGAGGAAGC
ATTTAATGATCCAAGCAGAGAAAAACTAATCTCTTTTGCTCAAAATACAAAAAGAGCAATTCAGGAAGCA
ACTCCAATACTGCAAAAAGATTTAGGTTGGGGAGATTATTTAACCAATTTAGCGAAACAATTGGTTAATG
CAGTGACCTTTGCTGTGGCTTATGCTGTAACTTTTGGAACCACCGGGCATCAAGGCTTTTTTGCTTTGAA
ATCTTCTCTGGCGGTTAGTCAATCTCAAAATCTTGTAGAGGCACTCAATAGCGAATTGAGTCAAAAAAAC
TGTTAG

Reference
(1) Rolando M; Buchrieser C (2012). Post-translational modifications of host proteins by Legionella pneumophila: a sophisticated survival strategy. Future Microbiol. 7(3):369-81. [PudMed:22393890]
(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature