| Effector Protein ID: 296106033 |
 T4SS name [ID] | Dot/Icm [43] |
| Gene symbol | - |
| Locus tag | lpa_00739 |
| Strain | Legionella pneumophila 2300/99 Alcoy |
| Replicon | chromosome [GenBank: NC_014125] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 569298..570785 [+] |
| Product | ankyrin repeat-containing protein |
| Effector type | Protein |
| Descripton | AnkC/legA12 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | D5T8P5 |
| KEGG ID | lpa:lpa_00739 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Ank_2 [PF12796], Evalue: 2e-08, Aligned region: 197..287 |
| Protein Sequence: 495 a.a. [Download] |
| >gi|296106033|ref|YP_003617733.1| ankyrin repeat-containing protein [Legionella pneumophila 2300/99 Alcoy] MDFVSEMNKILQMELEQFKEFIQKKLEEDKNYLEKLFWLPNGSQMTVLNYLIEQYSEPKLGIDDANRDLL AKIDFVLHEAKDVNVGEPLHQAIVAGKISLALHLLGVDENNFTPGESEKTDVLSILSKVKKKIEESFNHV KRCFFDVDKRDGYGRTLLSLALDAKRQELLIAILARNPIVHATTLRSSAYVPFQPIHQAVVLDYAEGITL LASMGAQLTNPLGSMRDTPVILAARLGKINALAALLELPTQSLSLESENNHLFEDKQTGHTAVEELCERM ANENDKAEALRGIAMLICRGAEPPRNEKMRNLLSSNRVAFLKAVSTYLADKPQLVDAFVERCHLRESALH NIVYADHSWGSSIRHLLGVPSEAALIVEELVTRKYSDPSFASENVSSLSTTATENLRSERNPLKLYAEFV RRYTQAYDSQMITNRWSTMRWMIAEGNCDWDTVVRYSKNHPTSRTRIVLNEMFNPIPRVHEDIESQQNSP RVVLK |
| - |
| Nucleotide Sequence: 1488 bp [Download] |
| >gi|296105497|ref|NC_014125.1|:569298-570785 Legionella pneumophila 2300/99 Alcoy chromosome, complete genome ATGGATTTTGTAAGTGAAATGAATAAGATTCTACAAATGGAATTAGAGCAATTTAAAGAATTTATTCAAA AGAAGCTGGAAGAAGATAAAAATTATTTAGAAAAGTTATTTTGGTTGCCGAATGGTTCTCAAATGACTGT TTTAAATTATTTGATCGAACAATACTCTGAGCCTAAGCTTGGTATAGACGATGCAAATAGGGATTTGCTT GCCAAAATAGATTTTGTCCTTCACGAGGCTAAAGATGTGAATGTTGGTGAGCCTTTGCACCAGGCAATTG TTGCTGGAAAAATTTCCTTGGCACTCCATCTGCTGGGAGTGGATGAAAATAATTTCACACCCGGGGAGAG TGAAAAAACGGATGTTTTGAGTATTTTGTCTAAAGTAAAGAAAAAAATCGAAGAGTCTTTTAATCACGTA AAAAGATGTTTTTTTGATGTGGATAAACGGGATGGTTATGGGCGCACTTTGTTGTCTTTGGCATTAGATG CCAAACGCCAGGAACTGTTAATTGCCATTTTAGCAAGGAATCCCATTGTACACGCAACAACGTTAAGATC CTCAGCCTATGTTCCTTTCCAGCCTATTCATCAGGCTGTTGTTTTAGATTATGCAGAGGGCATTACCTTA TTAGCCAGCATGGGGGCGCAATTGACAAATCCCCTGGGTAGTATGAGAGACACTCCGGTCATTTTGGCTG CTCGTTTGGGGAAAATAAATGCACTGGCGGCTTTACTGGAGTTACCCACTCAAAGTTTGTCTCTTGAATC CGAAAACAATCATTTATTCGAAGACAAACAAACTGGCCATACAGCAGTGGAAGAGTTATGTGAACGCATG GCCAATGAGAATGATAAAGCAGAGGCTCTTCGTGGGATTGCCATGCTAATATGCCGTGGTGCTGAACCAC CTCGCAATGAAAAAATGCGAAATTTATTAAGCAGCAACCGGGTTGCTTTCTTAAAAGCGGTCAGTACCTA TTTGGCAGATAAGCCTCAATTGGTCGATGCTTTTGTAGAGCGTTGTCATCTACGAGAAAGTGCTTTGCAT AATATAGTTTATGCCGATCATTCATGGGGGAGTTCTATTCGTCATTTACTCGGTGTTCCCAGTGAGGCGG CCCTTATTGTTGAAGAATTAGTAACGAGAAAATACAGTGATCCTTCCTTTGCCAGCGAAAATGTTTCGTC ATTATCAACTACTGCTACGGAAAATCTACGTTCAGAGAGGAACCCACTGAAACTCTATGCCGAATTTGTC AGGCGATACACGCAAGCATATGATAGCCAAATGATTACCAATCGTTGGAGTACCATGCGCTGGATGATCG CCGAAGGGAATTGTGATTGGGATACAGTAGTTCGGTATTCGAAAAATCATCCAACGAGCCGTACCAGGAT TGTGTTGAATGAAATGTTTAACCCGATACCGAGGGTACATGAGGATATTGAGTCTCAACAGAATTCTCCA AGAGTTGTCCTAAAATAA |
| Reference |
(1) Gomez-Valero L et al. (2014). Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires' disease. Genome Biol. 15(11):505. [PudMed:25370836] 
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(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| experimental literature |
| in silico analysis literature |