| Effector Protein ID: 295815283 |
 T4SS name [ID] | Dot/Icm [42] |
| Gene symbol | - |
| Locus tag | LPC_2598 |
| Strain | Legionella pneumophila str. Corby |
| Replicon | chromosome [GenBank: NC_009494] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 867467..869125 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | Lem3 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Lem3 reverses AnkX-mediated modification on Rab1 as a dephosphorylcholinase (Tan, et al, 2011) |
| UniProt ID | A5IGL3 |
| KEGG ID | lpc:LPC_2598 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 552 a.a. [Download] |
| >gi|295815283|ref|YP_001251859.2| hypothetical protein LPC_2598 [Legionella pneumophila str. Corby] MRDKIITGNKVIFSQSVAKDQTKNLSSFLSNRFYSVNQSHNHSIIIGSSLSHQENDIEHDTILDTSGMLV TTDTNGLVNGARVAITDGLGGGNGDQEEDDEIYRVSHSSCENFLNCNQNMDTTLSLITQPKASDKKQTAP KTLQHTEASMAAFIYQNHPGKGYIGQFANIGDGLIIILDKRFKIKHMVSACHIYRGFGTWTPPSLQALAT TANKDALLVRQTLKLAEGDIIISMTDGVWGELKTSLIAQTNDRRDIGVDKEYFKTLFDELTDSPYPSSFD IARIITSSAMSRSLERRKTLIKLINEIEQQHFHEKSVKTINEVLEYFLKTGHVETAQTLKAILFEDGLSD GITYFENIEIPLEMVMHDLKSRTVGDCSTINVTRIPYHLDELIRGFINYPEKHQILAPLFKARVKSEADL EEAFHRLSLEMVQAEIECPISEAHFERAFKKETLDKTQAVLTHYFRISTGLDSKKNYQERLNDLSAYLSK ESSLEKNDIKLLLSMLDSEIKPKTGVFQTLFGENQNKLYKAFHKKIELQFLDGEIENKNELK |
| - |
| Nucleotide Sequence: 1659 bp [Download] |
| >gi|295815281|ref|NC_009494.2|:c869125-867467 Legionella pneumophila str. Corby chromosome, complete genome ATGAGAGATAAAATTATCACTGGGAATAAAGTTATTTTTTCACAATCCGTTGCAAAAGACCAAACAAAAA ATTTATCAAGCTTTTTATCTAATCGGTTTTACTCTGTAAATCAAAGCCATAATCATTCCATTATTATCGG TTCCAGTCTTTCTCACCAAGAGAATGATATCGAACACGATACCATACTCGATACATCAGGCATGTTAGTG ACTACTGATACAAATGGCCTCGTTAACGGGGCAAGAGTCGCAATTACTGACGGTCTGGGTGGTGGAAATG GCGATCAAGAAGAAGACGACGAGATATACAGAGTATCTCATTCCAGTTGCGAGAATTTTTTGAATTGCAA CCAAAATATGGATACGACTCTAAGCTTGATTACCCAACCAAAGGCCTCTGATAAAAAACAAACAGCACCG AAAACGTTGCAGCATACAGAAGCGTCGATGGCTGCTTTTATTTATCAAAATCATCCGGGAAAAGGATACA TAGGTCAATTTGCAAATATTGGTGATGGACTAATTATTATCCTGGATAAACGTTTTAAGATAAAGCATAT GGTATCCGCATGCCATATATATCGCGGATTTGGTACCTGGACTCCACCATCCCTGCAAGCCCTGGCAACA ACTGCAAATAAAGACGCCCTGCTTGTCAGACAAACACTTAAACTTGCAGAAGGCGATATTATAATATCAA TGACTGATGGGGTTTGGGGGGAGCTGAAAACCAGTTTGATTGCTCAAACCAATGACCGTCGAGATATAGG AGTGGATAAAGAATATTTCAAAACGCTATTTGACGAATTGACAGACTCCCCCTACCCTTCTTCATTTGAT ATTGCTCGCATCATTACCAGTAGCGCAATGTCTCGAAGTTTGGAACGCAGAAAAACATTAATAAAATTAA TTAATGAAATAGAACAACAACACTTCCATGAAAAATCTGTCAAAACCATTAATGAAGTCCTGGAATATTT TCTTAAGACAGGCCATGTGGAAACAGCACAGACATTAAAAGCAATTCTCTTTGAAGACGGTTTGAGTGAT GGAATAACTTATTTTGAAAATATTGAAATCCCGCTGGAGATGGTAATGCACGATTTAAAAAGTCGTACCG TCGGTGATTGTTCAACCATCAATGTAACGCGCATTCCCTATCATTTAGATGAGCTCATACGAGGTTTTAT CAATTACCCTGAGAAACATCAAATCCTGGCGCCACTATTTAAAGCAAGGGTAAAATCTGAGGCTGATTTA GAAGAGGCATTTCATCGCCTGTCACTTGAAATGGTACAAGCTGAAATCGAGTGCCCAATTTCTGAAGCTC ATTTTGAACGTGCTTTTAAAAAAGAAACCCTTGATAAAACTCAGGCTGTCTTAACTCACTATTTTCGTAT TTCGACTGGTTTAGATAGTAAAAAAAATTATCAGGAACGATTAAATGATCTGAGTGCTTACTTATCTAAG GAATCCTCTCTCGAAAAAAATGATATTAAATTGCTATTATCTATGCTAGATAGTGAAATAAAACCTAAAA CCGGGGTTTTCCAAACATTGTTTGGGGAAAACCAAAATAAATTATACAAGGCATTTCACAAAAAAATCGA GTTGCAATTCTTGGATGGTGAAATAGAAAATAAAAATGAATTGAAATAG |
| Reference |
| (1) Rolando M; Buchrieser C (2012). Post-translational modifications of host proteins by Legionella pneumophila: a sophisticated survival strategy. Future Microbiol. 7(3):369-81. [PudMed:22393890] |
(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |