| Effector Protein ID: 289166618 |
 T4SS name [ID] | Dot/Icm [44] |
| Gene symbol | vipF |
| Locus tag | LLO_3312 |
| Strain | Legionella longbeachae NSW150 |
| Replicon | chromosome [GenBank: NC_013861] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 3886622..3887533 [+] |
| Product | N-terminal GNAT family acetyltransferase |
| Effector type | Protein |
| Descripton | VipF |
| T4CP requirement | T4CP Depedent |
| Target/Effection | VipF has been found to inhibit lysosomal protein trafficking in yeast (Shohdy, et al. 2005) |
| UniProt ID | D3HMS6 |
| KEGG ID | llo:LLO_3312 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Acetyltransf_1 [PF00583], Evalue: 3.5e-23, Aligned region: 52..106 Acetyltransf_1 [PF00583], Evalue: 3.5e-23, Aligned region: 195..268 Acetyltransf_7 [PF13508], Evalue: 2.8e-19, Aligned region: 47..102 Acetyltransf_7 [PF13508], Evalue: 2.8e-19, Aligned region: 188..269 Acetyltransf_10 [PF13673], Evalue: 6.3e-16, Aligned region: 178..268 Acetyltransf_3 [PF13302], Evalue: 2e-12, Aligned region: 43..101 Acetyltransf_3 [PF13302], Evalue: 2e-12, Aligned region: 188..268 FR47 [PF08445], Evalue: 4.9e-10, Aligned region: 207..272 Acetyltransf_4 [PF13420], Evalue: 3.1e-09, Aligned region: 178..268 |
| Protein Sequence: 303 a.a. [Download] |
| >gi|289166618|ref|YP_003456756.1| N-terminal GNAT family acetyltransferase [Legionella longbeachae NSW150] MLSNTNQLTEDQLKDLEQLKAICKKSDGSVPNLYTHLLTQKRNFPTILLNYENQKLIGFLSVYFFYDDAV EVSLLIHPSFRRQGMAKKLLRSILPLIKEQNFFKLIFSSPAHLNHHWLPDLGCSYMHSEYYMERNDLSPL LDYKKDLTFRTATLKDIPFLCVLDESCFFKKQAELIPRFEHILGDRNYQIILAFEDNHIVGKAHLRWQKD GATLSDIAVLPIRQGKGLGTALIAHCINFALSEGKPHLNLDVETHNQKALNLYSRLGFLTQNACDYWEID LYQLEKLIKQKRGNQEESKAEDK |
| - |
| Nucleotide Sequence: 912 bp [Download] |
| >gi|289163353|ref|NC_013861.1|:3886622-3887533 Legionella longbeachae NSW150 chromosome, complete genome ATGCTAAGTAATACAAATCAACTCACTGAGGATCAACTTAAGGATCTAGAACAATTAAAAGCCATCTGTA AAAAAAGCGATGGCAGTGTTCCCAATTTATATACTCATTTATTAACCCAAAAAAGAAACTTTCCAACTAT TTTGTTGAACTATGAAAACCAAAAATTAATCGGTTTCTTAAGTGTTTATTTTTTTTATGATGATGCCGTA GAAGTTTCTCTGCTTATACATCCATCTTTTCGTCGCCAGGGTATGGCTAAAAAATTGCTTCGGAGTATTT TACCTCTTATAAAGGAACAAAATTTTTTCAAACTAATATTTTCAAGTCCTGCTCATTTAAATCACCATTG GCTACCTGATCTTGGATGTTCCTATATGCATAGCGAATACTACATGGAACGTAATGATTTAAGCCCTTTG CTCGATTATAAAAAGGACTTAACTTTTCGTACCGCAACCCTTAAAGATATTCCTTTTCTTTGTGTTCTGG ACGAATCCTGTTTTTTTAAAAAGCAAGCAGAATTAATTCCACGTTTCGAACACATACTCGGTGATAGAAA CTATCAAATAATACTCGCTTTTGAAGACAACCATATCGTTGGGAAAGCCCATTTACGTTGGCAAAAGGAT GGAGCAACACTTTCAGATATTGCTGTATTACCCATCAGACAAGGGAAAGGATTGGGAACCGCCTTGATAG CGCACTGTATTAATTTTGCATTAAGTGAAGGAAAACCACATCTTAATCTCGATGTGGAAACACATAATCA AAAAGCACTTAACCTATATTCTCGTCTTGGTTTCCTCACGCAAAATGCATGTGATTATTGGGAAATTGAT CTCTACCAATTGGAAAAACTCATAAAACAGAAACGTGGAAATCAGGAAGAGTCTAAAGCAGAGGATAAGT AG |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |