| Effector Protein ID: 289163929 |
 T4SS name [ID] | Dot/Icm [44] |
| Gene symbol | AnkH |
| Locus tag | LLO_0584 |
| Strain | Legionella longbeachae NSW150 |
| Replicon | chromosome [GenBank: NC_013861] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 663072..664475 [+] |
| Product | substrate of the Dot/Icm secretion system |
| Effector type | Protein |
| Descripton | AnkH/legA3, ankW |
| T4CP requirement | T4CP Depedent |
| Target/Effection | AnkH is required for intracellular replication |
| UniProt ID | D3HPV3 |
| KEGG ID | llo:LLO_0584 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Ank_2 [PF12796], Evalue: 1.8e-23, Aligned region: 19..93 Ank_2 [PF12796], Evalue: 1.8e-23, Aligned region: 60..124 Ank [PF00023], Evalue: 7.4e-16, Aligned region: 65..95 Ank_4 [PF13637], Evalue: 3.8e-14, Aligned region: 34..85 Ank_4 [PF13637], Evalue: 3.8e-14, Aligned region: 65..110 Ank_5 [PF13857], Evalue: 1.4e-13, Aligned region: 19..68 Ank_5 [PF13857], Evalue: 1.4e-13, Aligned region: 56..102 Ank_3 [PF13606], Evalue: 1.4e-12, Aligned region: 65..93 |
| Protein Sequence: 467 a.a. [Download] |
| >gi|289163929|ref|YP_003454067.1| substrate of the Dot/Icm secretion system [Legionella longbeachae NSW150] MTIASDIISHQMPDFESYLRAGESLDDIDEYGFTPLIECAITRQIEIAEQLIIRKVDVNKTDVTGRTPLH WAVDNNDVAFARLLLENGADPNAYTRNGLSVLVYPVLRGQDVLKHVLYNYGAKLDFALDFINGKLLGHRF ELQGDVDIVNSRDEFIELDYEGFILEFTVSAIKDALRRFISSFSTRHLREFFPFAHTIIDAFTIAEELLQ YQHLPFLDRQHLVRLQTLVNASMLILPAASRGHAMGFIRLRQWWAKIDRGENSLKEGSVNIYKITRPEAF DSYFLHDFLYKKQARTYFHQMINQQLGLVPVAKMPISSQISGNCSWANIQAIVAVAYAIQELEKTNQFNP DPALAFYNEWVVWDKERAIDECIQRFHLAGPTRKASLAAMLGGVLFQACDYGKKRDLEMAEKILKVLTLP EYEYILKSYLEEYCIKRLTKRGNNLLKILDDCGVNPNIGINPIATGL |
| - |
| Nucleotide Sequence: 1404 bp [Download] |
| >gi|289163353|ref|NC_013861.1|:663072-664475 Legionella longbeachae NSW150 chromosome, complete genome ATGACAATTGCAAGTGACATAATCAGTCATCAAATGCCTGATTTTGAATCTTATCTTAGGGCAGGGGAGT CGTTAGATGACATTGATGAGTATGGTTTTACGCCTTTAATCGAGTGTGCTATTACTCGTCAAATTGAAAT TGCCGAGCAATTAATTATTCGTAAAGTGGATGTGAATAAAACTGATGTAACTGGACGTACCCCTTTGCAT TGGGCTGTAGATAATAATGATGTGGCGTTCGCACGTCTATTATTAGAAAATGGAGCAGACCCTAATGCCT ATACACGCAATGGACTTTCTGTATTGGTCTATCCGGTACTCCGTGGTCAGGATGTACTCAAACACGTGCT CTATAATTATGGGGCAAAGCTTGATTTTGCGCTGGATTTCATTAATGGCAAACTTTTGGGGCATCGGTTC GAACTACAAGGAGATGTCGATATCGTAAATTCCAGGGATGAGTTTATTGAACTGGATTATGAAGGCTTTA TACTGGAATTTACTGTTTCTGCAATAAAAGATGCTTTAAGGCGTTTTATTAGTAGTTTTTCAACACGGCA TTTACGGGAATTTTTCCCATTTGCTCATACCATAATTGATGCATTTACTATTGCTGAGGAGCTTTTGCAA TATCAGCATTTGCCATTTTTGGACAGACAACATCTTGTACGGTTGCAAACACTCGTAAACGCATCTATGT TAATATTGCCCGCAGCAAGTCGTGGCCATGCTATGGGCTTTATCCGTTTGAGGCAGTGGTGGGCAAAAAT TGACAGGGGTGAAAATAGTCTAAAAGAAGGGAGTGTCAATATTTATAAGATCACGAGACCAGAGGCTTTT GATAGTTACTTTTTGCACGATTTTTTATATAAAAAACAAGCAAGGACTTATTTTCATCAAATGATCAACC AACAATTAGGGTTAGTTCCTGTAGCAAAAATGCCCATTAGTTCACAGATTAGTGGTAATTGTTCCTGGGC TAATATCCAAGCTATAGTAGCAGTGGCTTATGCTATTCAAGAGTTGGAGAAAACGAATCAGTTTAACCCT GATCCGGCCCTCGCTTTTTATAATGAGTGGGTTGTGTGGGATAAAGAAAGGGCAATCGATGAGTGCATTC AACGCTTTCATTTGGCAGGGCCAACCCGCAAGGCAAGTCTTGCGGCAATGCTTGGAGGTGTTTTATTTCA AGCGTGTGATTATGGGAAGAAGCGCGACCTGGAAATGGCTGAAAAAATACTCAAAGTTCTAACCTTACCC GAATATGAATACATTTTGAAAAGCTACCTTGAAGAATATTGTATTAAACGGTTAACCAAAAGAGGGAATA ATTTACTTAAAATCCTTGATGACTGTGGCGTAAATCCTAACATAGGTATTAATCCTATTGCTACAGGTTT ATAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
|
| in silico analysis literature |