| Effector Protein ID: 289163671 |
 T4SS name [ID] | Dot/Icm [44] |
| Gene symbol | - |
| Locus tag | LLO_0327 |
| Strain | Legionella longbeachae NSW150 |
| Replicon | chromosome [GenBank: NC_013861] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 370108..371544 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | LegG2 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | LegG2, which has a Ras GEF domain, is believed to be involved in GDP-to-GTP exchange in Ras GTP-binding protein (de Felipe, et al. 2005) |
| UniProt ID | D3HP42 |
| KEGG ID | llo:LLO_0327 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | RasGEF [PF00617], Evalue: 7.3e-10, Aligned region: 56..218 |
| Protein Sequence: 478 a.a. [Download] |
| >gi|289163671|ref|YP_003453809.1| hypothetical protein LLO_0327 [Legionella longbeachae NSW150] MPKILDGHVYQEMENELNNLFDQIYKHNKKDRTQITSQVQQFLDNLSESIRDHSRLLFTKISPEEIIYHK ENKPGDSRDKFQNLDKMTHYFNNLSALINFSVMQQEDPTLRVFYYDMYIQLMNFCYLKGDLFGAGAIYTG LIANNLPNSIDQKKLSSESRLIWNAREVELTRLFNLSTTYKAHMDLKEKLQTPFIPVLSSILPVQIYTKD AYDNSVSEHNRIQDGLRKLDLEHNKMLNRMQLESFSWSKPYYDYMKKVYLPQSISEYTKLVREHEELIVD HGGPIAKQFHQDKNSKPLVNFVESTLLENQLVLKLSPFQNQRIVDMLSEIDVVKSECLDLPQFDELSWKM REMNCTLVKAKSIGEYTTKIFASLDTPPIEENMHENPIPVGSEELRPEDLYQPYPHTGLKLMLELERAIT EHKPTIGSPGTVNCGFFSRAKRGNKNVNLETMDLKIMDVGDVDHGEIELRDHTIMVLV |
| - |
| Nucleotide Sequence: 1437 bp [Download] |
| >gi|289163353|ref|NC_013861.1|:370108-371544 Legionella longbeachae NSW150 chromosome, complete genome ATGCCAAAAATTTTAGATGGTCATGTGTATCAAGAGATGGAAAATGAGCTTAATAATCTTTTCGATCAAA TATATAAACATAATAAAAAAGACAGAACTCAAATCACATCACAAGTTCAGCAGTTTTTAGACAATTTAAG TGAATCCATTAGGGATCATTCACGCTTATTATTTACAAAAATTTCTCCAGAAGAAATTATTTATCACAAA GAGAATAAGCCTGGGGATTCACGGGATAAATTCCAAAACCTCGATAAGATGACCCATTATTTTAACAATC TATCCGCCCTGATTAATTTCTCGGTCATGCAGCAAGAAGATCCTACGCTACGGGTTTTTTATTATGACAT GTACATTCAATTAATGAATTTTTGCTATCTTAAAGGCGATTTATTTGGTGCTGGTGCGATTTATACCGGG TTGATAGCAAATAATCTCCCCAACTCCATTGATCAGAAAAAATTAAGCTCTGAGAGCCGCTTGATTTGGA ACGCACGTGAAGTGGAATTGACTCGACTGTTCAATTTATCAACTACTTATAAAGCACACATGGATTTAAA AGAAAAATTACAAACCCCTTTTATTCCAGTATTATCATCAATTCTTCCTGTTCAAATATATACTAAAGAT GCGTACGATAATTCAGTCAGTGAGCATAATAGAATTCAGGATGGTTTGCGTAAGTTGGATTTGGAACATA ATAAGATGCTGAATCGTATGCAATTAGAATCTTTTTCCTGGTCAAAACCTTATTATGATTATATGAAAAA GGTCTATCTCCCACAAAGTATATCGGAGTACACCAAGCTTGTAAGAGAACACGAAGAACTGATAGTTGAT CATGGTGGCCCTATTGCCAAGCAGTTTCATCAAGATAAAAACTCAAAACCTTTAGTGAATTTTGTCGAGT CGACATTATTAGAAAATCAATTGGTTCTGAAGTTATCTCCTTTCCAAAATCAGAGAATTGTCGATATGCT TTCAGAAATTGATGTAGTAAAAAGTGAGTGTCTAGACTTACCCCAGTTTGATGAGCTCTCCTGGAAGATG AGAGAAATGAATTGCACCTTGGTAAAAGCAAAATCCATTGGAGAGTATACGACCAAAATTTTTGCCAGTC TGGATACGCCTCCCATCGAAGAAAATATGCATGAAAATCCAATCCCAGTTGGTTCGGAAGAACTACGTCC AGAAGATCTCTACCAGCCTTATCCTCATACCGGTCTGAAATTAATGCTTGAGCTTGAACGAGCTATAACA GAACACAAACCAACTATTGGCTCACCAGGTACTGTTAATTGTGGCTTTTTTAGCAGAGCCAAAAGAGGAA ATAAGAATGTGAATTTGGAAACAATGGATCTGAAGATTATGGATGTTGGTGACGTAGACCATGGTGAAAT CGAGTTACGCGATCACACTATTATGGTCCTGGTTTAG |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |