SecReT4
Effector Protein ID: 23502136
T4SS name [ID]VirB [378]
Gene symbol-
Locus tagBR1260
StrainBrucella suis 1330
Repliconchromosome II [GenBank: NC_004310] [Browse all T4SS(s) in this replicon]
Location [Strand]1224775..1225302 [-]
Productferripyochelin-binding protein
Effector typeProtein
DescriptonRicA
T4CP requirementT4CP Indepedent
Target/EffectionRicA was demonstrated to interact with human small GTPase Rab2 involved in trafficking
UniProt IDQ8G055
KEGG IDbms:BR1260, bsi:BS1330_I1256
PDB IDNA
Domain hit(s) vs Pfam Hexapep [PF00132], Evalue: 2.6e-19, Aligned region: 17..47
Hexapep [PF00132], Evalue: 2.6e-19, Aligned region: 75..105
Hexapep [PF00132], Evalue: 2.6e-19, Aligned region: 90..124
Protein Sequence: 175 a.a.     [Download]
>gi|23502136|ref|NP_698263.1| ferripyochelin-binding protein [Brucella suis 1330]
MPIYAYNGHKPQFADRESNWIAPDATLIGKVVVGENAGFWFGAVLRGDNEPITIGADTNVQEQTIMHTDI
GFPLTIGAGCTIGHRAILHGCTIGENTLIGMGAIVLNGAKVGKNCLIGAGTLVKEGMEIPDNSLVVGSPA
RVLRQLDDAAVEKLRASAKHYVERGHSFMRGMEPA
-
Nucleotide Sequence: 528 bp     [Download]
>gi|56968325|ref|NC_004310.3|:c1225302-1224775 Brucella suis 1330 chromosome I, complete sequence
ATGCCGATCTATGCATATAACGGGCACAAGCCGCAGTTTGCGGACCGCGAGAGCAACTGGATTGCACCGG
ATGCGACGCTGATCGGCAAGGTGGTCGTGGGCGAGAATGCGGGTTTCTGGTTCGGCGCGGTGTTGCGCGG
CGATAATGAGCCAATCACTATCGGTGCCGATACCAATGTGCAGGAACAGACGATCATGCACACCGATATC
GGCTTTCCGCTGACCATCGGTGCGGGCTGCACTATCGGGCACCGTGCGATTCTCCATGGCTGCACGATTG
GCGAGAATACTCTTATCGGCATGGGCGCGATTGTGCTCAATGGCGCGAAGGTCGGCAAGAATTGCCTTAT
CGGGGCGGGAACATTGGTGAAAGAAGGGATGGAAATCCCTGATAATTCGCTTGTTGTCGGCTCTCCCGCG
CGTGTCCTGCGCCAGCTTGACGATGCTGCCGTTGAAAAGCTGCGGGCCTCTGCAAAGCATTATGTGGAGA
GGGGACATTCCTTCATGCGCGGCATGGAGCCTGCCTGA

Reference
(1) de Jong MF; Tsolis RM (2012). Brucellosis and type IV secretion. Future Microbiol. 7(1):47-58. [PudMed:22191446]