| Effector Protein ID: 222080234 |
 T4SS name [ID] | VirB [14] |
| Gene symbol | virD2 |
| Locus tag | Avi_8212 |
| Strain | Agrobacterium vitis S4 |
| Replicon | plasmid pTiS4 [GenBank: NC_011982] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 155516..156727 [-] |
| Product | type IV secretion system T-DNA border endonuclease VirD2 |
| Effector type | Protein |
| Descripton | VirD2 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | VirD2 is an endonuclease that nicks the T-DNA region of Ti-/Ri-plasmids at border repeat sequences flanking T-DNA. During T-DNA processing, VirD2 covalently attaches to the 5' end of the resulting T-strand. VirD2 serves as a "pilot protein" to lead T-strands through the T4SS and into the host cell. Once in the host, VirD2 probably plays a major role in targeting T-strands to the nucleus |
| UniProt ID | B9K403 |
| KEGG ID | avi:Avi_8212 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Relaxase [PF03432], Evalue: 2.9e-31, Aligned region: 16..200 |
| Protein Sequence: 403 a.a. [Download] |
| >gi|222080234|ref|YP_002540097.1| endonuclease [Agrobacterium vitis S4] MPDRSQVIIRIVPGGGTKTLQQIINQLEYLSRKGTLELQRSARHLDIFVPPDNIRDLARSWIQETGTYDE SQPDEERQKELTTHIIVSFPAGTSQPAAYAASREWAAETFGSGEGGGQYNYLTAFHTDRDHPHLHVVVNR RELLGHKWLKISRRHPQLNYDALRTRMAKVSFRHGIVLEATRRAERGITERPMTFAQYRRLERQQANQIR FDDPDFEHFTPGENDREPEQFFDSSYGERPQNLPESPERNEHLQPMSEGRSRARIGSNGDGRDVEGASGT GLAIESVTHPTSEDDVQQRLHRKRPRGDEDEDRGAKLTRVNRVRAGVAITDVPVTGDGPTSSIQAPGSNP SQTDIATDGLPATADRPQQGGPNSKRPRDEEAEPSIRKRSRDGRSQEDEGNRR |
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| Nucleotide Sequence: 1212 bp [Download] |
| >gi|222080117|ref|NC_011982.1|:c156727-155516 Agrobacterium vitis S4 plasmid pTiS4, complete sequence ATGCCCGATCGATCTCAAGTCATCATCCGCATTGTGCCAGGAGGTGGGACGAAGACCCTCCAACAAATTA TTAATCAATTGGAATATCTGTCCCGGAAGGGCACCTTGGAGCTGCAGCGTTCAGCACGGCATCTCGATAT TTTCGTACCACCGGATAATATCCGCGATCTCGCCCGAAGTTGGATTCAAGAAACCGGGACCTACGACGAA AGTCAGCCCGACGAGGAAAGGCAAAAGGAATTGACCACCCATATTATTGTAAGCTTCCCTGCTGGTACAA GTCAGCCAGCGGCTTATGCAGCGAGCCGCGAGTGGGCAGCCGAGACGTTCGGGTCAGGCGAAGGGGGAGG TCAATACAACTATCTTACGGCCTTCCACACTGATCGCGATCACCCACATTTGCATGTCGTCGTTAATCGT CGCGAACTCTTGGGACACAAGTGGCTGAAAATATCCCGGCGCCACCCTCAACTGAATTACGATGCCCTGC GCACTAGAATGGCCAAGGTTTCGTTTCGTCATGGCATCGTCCTGGAAGCGACCAGGCGAGCTGAGCGCGG CATCACCGAGCGGCCAATGACTTTTGCCCAGTATAGGCGCCTTGAGCGGCAGCAGGCCAATCAAATTCGT TTCGACGATCCTGATTTCGAACATTTCACGCCCGGCGAAAACGATCGCGAACCGGAACAATTCTTCGATT CGTCGTACGGTGAGCGACCGCAAAACCTGCCAGAAAGTCCGGAACGAAACGAGCATCTGCAACCGATGTC CGAAGGGCGTTCCCGGGCACGAATCGGATCGAACGGCGATGGCCGGGATGTTGAAGGCGCTTCCGGTACT GGTTTGGCGATCGAATCCGTCACGCACCCAACAAGCGAGGACGACGTTCAGCAACGACTTCATCGAAAAC GCCCTCGTGGTGATGAGGATGAGGACAGAGGCGCAAAACTGACTAGGGTAAACAGAGTTCGGGCGGGAGT GGCAATCACGGACGTACCGGTTACCGGGGACGGTCCGACATCGTCAATACAGGCTCCTGGATCAAACCCG TCGCAGACCGACATCGCTACGGATGGATTGCCTGCCACAGCCGATCGCCCGCAGCAGGGGGGCCCAAATT CTAAGCGTCCCCGTGATGAGGAAGCCGAGCCGAGCATTCGCAAGCGTTCAAGGGACGGACGCAGCCAAGA AGATGAGGGAAATAGAAGATAG |