Effector Protein ID: 212218047 |
T4SS name [ID] | Dot/Icm [158] |
Gene symbol | - |
Locus tag | CbuK_0401 |
Strain | Coxiella burnetii CbuK_Q154 |
Replicon | chromosome [GenBank: NC_011528] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 369951..371207 [+] |
Product | hypothetical membrane spanning protein |
Effector type | Protein |
Descripton | ElpA |
T4CP requirement | T4CP Depedent |
Target/Effection | ElpA contains a predicted ER structural motif, traffics to the host ER, and disrupts secretory transport. |
UniProt ID | NA |
KEGG ID | NA |
PDB ID | NA |
Domain hit(s) vs Pfam | NA |
Protein Sequence: 418 a.a. [Download] |
>gi|212218047|ref|YP_002304834.1| hypothetical membrane spanning protein [Coxiella burnetii CbuK_Q154] MVSRIIYDESEGEFKFQAEPPDQAFVAAADSFKKVVIVVNEVLDRVYADVKSSEVKSEDDDLQKKITFLN NIVSALASLHENPDSSLYNIHDISALVKEEYKVVLTQPRDFFLETPGMRIQDPETVRSLLEMAIWNYLSK TIGKIFQDEAASAVRRCLCQWINPEVILIMAQQKINRLVPLDAEDADMIVVYQGDRQLVIWRGLPEPEEK SEAPSTSESRRLSSLMIVFFFGVLVLGIYALTRSGLNANHNNRQLERLLSGLFASLIGIVGIMCSVQYWR RGNDFFIDLARSLRLFPRQSEVDLQERLLAAIANLNDERNEREEEEGLEGVPEEDPEHPLLINLQEGNNR HHNLFSLRAEEKSREGNSGGMVRQTPFLTVHEDRLVIRNFDEGPDKEILLSVKNVFSQNEEEAPRFNF |
- |
Nucleotide Sequence: 1257 bp [Download] |
>gi|212217688|ref|NC_011528.1|:369951-371207 Coxiella burnetii CbuK_Q154 chromosome, complete genome GTGGTGAGTCGAATAATTTATGATGAGAGTGAAGGAGAATTTAAATTTCAAGCAGAGCCGCCCGATCAAG CATTTGTTGCCGCGGCTGATTCCTTTAAAAAAGTGGTTATTGTTGTAAATGAAGTGCTGGATAGAGTGTA TGCTGACGTGAAGTCTTCGGAAGTCAAAAGCGAAGACGATGACTTACAGAAAAAAATCACGTTTTTAAAT AATATCGTAAGTGCCTTGGCTTCTTTGCATGAGAATCCAGATTCTTCGCTATATAATATCCATGATATCA GCGCCTTGGTGAAAGAGGAATATAAAGTTGTTTTAACTCAACCACGGGATTTTTTTCTGGAGACTCCTGG AATGAGGATCCAAGATCCCGAAACGGTTCGGTCGTTGTTGGAAATGGCTATCTGGAATTATCTCTCAAAA ACCATTGGAAAAATATTTCAGGATGAGGCGGCATCAGCCGTCAGGAGATGCCTTTGCCAATGGATAAATC CAGAAGTGATACTGATAATGGCACAACAGAAGATCAACAGACTCGTACCTTTGGATGCGGAAGATGCCGA CATGATCGTCGTATACCAGGGTGATCGACAGCTTGTCATTTGGAGAGGGCTACCGGAACCGGAGGAAAAA TCAGAAGCGCCTAGCACATCCGAATCACGTCGGTTGTCTTCCCTCATGATCGTTTTCTTTTTCGGAGTTT TAGTACTAGGGATTTATGCATTAACTCGCTCCGGTTTAAATGCAAATCACAACAATAGGCAGCTTGAACG GCTGCTGTCTGGATTGTTCGCATCTCTTATCGGTATCGTGGGAATTATGTGCTCTGTGCAATATTGGAGA AGAGGGAATGATTTTTTTATAGATTTAGCTCGAAGTTTGAGACTGTTCCCTCGTCAGTCTGAAGTTGATT TACAGGAACGATTATTAGCGGCAATAGCTAATCTTAATGATGAGAGAAACGAGAGAGAAGAAGAGGAAGG GCTGGAAGGGGTGCCAGAAGAAGATCCGGAGCACCCGTTATTGATTAATCTTCAGGAGGGTAATAATAGA CACCATAACCTTTTCTCCTTGAGGGCAGAGGAGAAAAGCCGGGAGGGGAATTCAGGTGGTATGGTTCGTC AAACTCCATTCTTAACTGTGCACGAAGACAGACTTGTCATTCGTAATTTTGATGAGGGTCCTGATAAGGA AATTCTACTGAGTGTGAAGAATGTTTTTTCACAAAACGAGGAAGAAGCCCCCAGATTTAACTTTTAA |
Reference |
(1) Graham JG et al. (2015). Identification of ElpA, a Coxiella burnetii pathotype-specific Dot/Icm type IV secretion system substrate. Infect Immun. 83(3):1190-8. [PudMed:25605765] |
experimental literature |