SecReT4
Effector Protein ID: 212218047
T4SS name [ID]Dot/Icm [158]
Gene symbol-
Locus tagCbuK_0401
StrainCoxiella burnetii CbuK_Q154
Repliconchromosome [GenBank: NC_011528] [Browse all T4SS(s) in this replicon]
Location [Strand]369951..371207 [+]
Producthypothetical membrane spanning protein
Effector typeProtein
DescriptonElpA
T4CP requirementT4CP Depedent
Target/EffectionElpA contains a predicted ER structural motif, traffics to the host ER, and disrupts secretory transport.
UniProt IDNA
KEGG IDNA
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 418 a.a.     [Download]
>gi|212218047|ref|YP_002304834.1| hypothetical membrane spanning protein [Coxiella burnetii CbuK_Q154]
MVSRIIYDESEGEFKFQAEPPDQAFVAAADSFKKVVIVVNEVLDRVYADVKSSEVKSEDDDLQKKITFLN
NIVSALASLHENPDSSLYNIHDISALVKEEYKVVLTQPRDFFLETPGMRIQDPETVRSLLEMAIWNYLSK
TIGKIFQDEAASAVRRCLCQWINPEVILIMAQQKINRLVPLDAEDADMIVVYQGDRQLVIWRGLPEPEEK
SEAPSTSESRRLSSLMIVFFFGVLVLGIYALTRSGLNANHNNRQLERLLSGLFASLIGIVGIMCSVQYWR
RGNDFFIDLARSLRLFPRQSEVDLQERLLAAIANLNDERNEREEEEGLEGVPEEDPEHPLLINLQEGNNR
HHNLFSLRAEEKSREGNSGGMVRQTPFLTVHEDRLVIRNFDEGPDKEILLSVKNVFSQNEEEAPRFNF
-
Nucleotide Sequence: 1257 bp     [Download]
>gi|212217688|ref|NC_011528.1|:369951-371207 Coxiella burnetii CbuK_Q154 chromosome, complete genome
GTGGTGAGTCGAATAATTTATGATGAGAGTGAAGGAGAATTTAAATTTCAAGCAGAGCCGCCCGATCAAG
CATTTGTTGCCGCGGCTGATTCCTTTAAAAAAGTGGTTATTGTTGTAAATGAAGTGCTGGATAGAGTGTA
TGCTGACGTGAAGTCTTCGGAAGTCAAAAGCGAAGACGATGACTTACAGAAAAAAATCACGTTTTTAAAT
AATATCGTAAGTGCCTTGGCTTCTTTGCATGAGAATCCAGATTCTTCGCTATATAATATCCATGATATCA
GCGCCTTGGTGAAAGAGGAATATAAAGTTGTTTTAACTCAACCACGGGATTTTTTTCTGGAGACTCCTGG
AATGAGGATCCAAGATCCCGAAACGGTTCGGTCGTTGTTGGAAATGGCTATCTGGAATTATCTCTCAAAA
ACCATTGGAAAAATATTTCAGGATGAGGCGGCATCAGCCGTCAGGAGATGCCTTTGCCAATGGATAAATC
CAGAAGTGATACTGATAATGGCACAACAGAAGATCAACAGACTCGTACCTTTGGATGCGGAAGATGCCGA
CATGATCGTCGTATACCAGGGTGATCGACAGCTTGTCATTTGGAGAGGGCTACCGGAACCGGAGGAAAAA
TCAGAAGCGCCTAGCACATCCGAATCACGTCGGTTGTCTTCCCTCATGATCGTTTTCTTTTTCGGAGTTT
TAGTACTAGGGATTTATGCATTAACTCGCTCCGGTTTAAATGCAAATCACAACAATAGGCAGCTTGAACG
GCTGCTGTCTGGATTGTTCGCATCTCTTATCGGTATCGTGGGAATTATGTGCTCTGTGCAATATTGGAGA
AGAGGGAATGATTTTTTTATAGATTTAGCTCGAAGTTTGAGACTGTTCCCTCGTCAGTCTGAAGTTGATT
TACAGGAACGATTATTAGCGGCAATAGCTAATCTTAATGATGAGAGAAACGAGAGAGAAGAAGAGGAAGG
GCTGGAAGGGGTGCCAGAAGAAGATCCGGAGCACCCGTTATTGATTAATCTTCAGGAGGGTAATAATAGA
CACCATAACCTTTTCTCCTTGAGGGCAGAGGAGAAAAGCCGGGAGGGGAATTCAGGTGGTATGGTTCGTC
AAACTCCATTCTTAACTGTGCACGAAGACAGACTTGTCATTCGTAATTTTGATGAGGGTCCTGATAAGGA
AATTCTACTGAGTGTGAAGAATGTTTTTTCACAAAACGAGGAAGAAGCCCCCAGATTTAACTTTTAA

Reference
(1) Graham JG et al. (2015). Identification of ElpA, a Coxiella burnetii pathotype-specific Dot/Icm type IV secretion system substrate. Infect Immun. 83(3):1190-8. [PudMed:25605765] experimental
 
experimental experimental literature