| Effector Protein ID: 165933520 |
 T4SS name [ID] | VirB [486] |
| Gene symbol | - |
| Locus tag | RrIowa_1113 |
| Strain | Rickettsia rickettsii str. Iowa |
| Replicon | chromosome [GenBank: NC_010263] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 881146..882408 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | Rickettsia ankyrin repeat protein 2 (RARP-2) |
| T4CP requirement | T4CP Depedent |
| Target/Effection | RARP-2 is secreted by a type IV secretion system into the cytosol of the host cell, where it interacts with and manipulates the structure of the endoplasmic reticulum. |
| UniProt ID | B0BUJ3 |
| KEGG ID | rrj:RrIowa_1113 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 420 a.a. [Download] |
| >gi|165933520|ref|YP_001650309.1| hypothetical protein RrIowa_1113 [Rickettsia rickettsii str. Iowa] MQKILFKGPNISMKNENPDIKEIKTLDDLPSGTGSEYFINVHGSEFFCKPTDLGLWGKIKSYFMPESSYL LMNIFSDEGTTPVLDITLLNKIQNNTTANQCNIVHIFSCHSGAAQHHLDWIQGNIVLCTYNKASDANIMR LAQNNYDARTKNNSLLIEYIRDHFHLLVASDFSISYKLDNQIYSFSLSANKIKQMKSIEELPAFLHKEYK AFVKFYENIHAKYHESYPEIFNLNIETKPKELTYDDLIKVFSRALTLETYNFNKFSLSKIETMLNQKGLC TDTSIRHAIEHGNSELLICLLNYGNTKVSTYTLDKAIEKGDLAILKAVLEHSTTKIALYNLGEAIEEGDL AILKAVLEHSTIEVGSSNIYTAEETHNLDVIELVKKYSTINTITSEENTIDTTLTVVEEVPVLGEGTEGV |
| - |
| Nucleotide Sequence: 1263 bp [Download] |
| >gi|319717301|ref|NC_010263.2|:c882398-881136 Rickettsia rickettsii str. Iowa chromosome, complete genome ATGCAAAAAATATTGTTTAAAGGCCCGAATATAAGTATGAAAAATGAAAATCCTGATATCAAGGAAATAA AAACCTTAGATGACTTACCTTCAGGTACAGGTAGTGAATATTTTATAAATGTACATGGATCAGAGTTTTT CTGTAAACCTACTGATTTAGGTTTATGGGGAAAAATTAAATCATATTTTATGCCTGAGTCTTCTTACTTA TTAATGAATATATTTTCTGATGAAGGTACAACTCCTGTATTAGATATTACACTACTTAATAAAATACAAA ATAATACCACTGCAAATCAATGTAATATTGTTCATATATTTTCTTGTCATTCAGGAGCCGCTCAACATCA TTTAGATTGGATACAGGGCAACATTGTGTTATGCACTTATAATAAGGCCAGCGATGCAAATATTATGCGA TTAGCTCAAAATAATTACGATGCTAGAACAAAAAATAACTCCTTATTGATTGAATATATAAGAGATCATT TCCATCTGCTAGTAGCATCAGATTTTAGTATAAGCTATAAATTAGACAATCAAATTTATAGTTTTTCTTT AAGTGCTAATAAAATCAAACAGATGAAAAGCATAGAGGAGTTGCCGGCTTTTCTACATAAAGAATATAAA GCTTTTGTAAAATTTTATGAAAATATTCATGCGAAATATCATGAATCATATCCTGAAATATTTAACTTAA ATATAGAAACAAAGCCGAAAGAATTAACATACGATGACTTAATCAAGGTATTTAGTAGAGCTTTAACCTT AGAAACATATAATTTTAATAAATTTTCTTTAAGCAAGATAGAGACTATGTTAAATCAGAAAGGATTATGT ACTGATACTAGTATAAGGCACGCTATAGAGCACGGGAATTCTGAACTATTAATTTGTTTACTTAATTATG GTAATACTAAAGTCAGTACCTATACTCTTGATAAGGCTATAGAGAAAGGTGATTTAGCTATTCTAAAAGC TGTACTTGAGCATAGTACTACAAAAATAGCATTATATAATCTTGGTGAGGCTATAGAGGAAGGTGATTTA GCTATTCTAAAAGCTGTACTTGAGCATAGTACTATAGAGGTAGGTAGCTCTAATATTTATACGGCAGAAG AGACGCATAATTTAGACGTTATCGAATTAGTAAAAAAATATTCTACTATAAATACTATTACATCTGAAGA AAACACTATAGATACAACACTTACTGTGGTAGAAGAAGTACCGGTATTAGGAGAGGGGACAGAGGGAGTA TAA |
| Reference |
(1) Lehman SS et al. (2018). The Rickettsial Ankyrin Repeat Protein 2 Is a Type IV Secreted Effector That Associates with the Endoplasmic Reticulum. MBio. 9(3):e00975-18. [PudMed:29946049] 
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| experimental literature |