Effector Protein ID: 163868791 |
T4SS name [ID] | VirB [225] |
Gene symbol | bepF |
Locus tag | Btr_1709 |
Strain | Bartonella tribocorum CIP 105476 |
Replicon | chromosome [GenBank: NC_010161] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 1821138..1823105 [+] |
Product | hypothetical protein |
Effector type | Protein |
Descripton | BepF |
T4CP requirement | T4CP Depedent |
Target/Effection | Homologous to BepF protein of Bartonella henselae. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. |
UniProt ID | A9IWQ4 |
KEGG ID | btr:Btr_1709 |
PDB ID | NA |
Domain hit(s) vs Pfam | NA |
Protein Sequence: 655 a.a. [Download] |
>gi|163868791|ref|YP_001610015.1| hypothetical protein Btr_1709 [Bartonella tribocorum CIP 105476] MKKRNPSPLIAEMMAKFQQQAEQSPTSPSHSQVSQSVPKPPVQKRPENLSHPPKVAPPPPLRMRDKTPAD TKIQKPETQESSSAHIKTPPQRPPRAKDREQNKQTAQESPSLQTKMAPPKPPRIKDKTPADTKIQKPETQ ESSSAHIKTPPQRPPRAKDREQNKQTAQESPSLQTKMAPPKPPRIKDKTPADTKIQKPETQESSSAHIKT PPPKPPRAKDREQNKQTAQESPSLQTKMPPPTPPRIKDKTPANATIQVQTSTKNQNLETIAPSVRPKTPQ HRQVRQQSSSSSQNSESYAVPPSRKPHQIGDRQKSEAAIQKTAIRQPKPSQERKASINTMEKKLLLEAYH EEIRFLCKKTFGDRLILESRIEAIKENPNMGEQLLWDVTKKPQSISKLAGRKVLGIKNGARKQAEETLSP LYAAIEGFVYTAKYVQENTSQNSHTKQQQHQQAQQEGAISQHARNPLHSEKKIQPLSNQEIARRVQQNPS VQYGQREVQYWCQKVYRDPFIFNDRMEDMQKIPEIGEELVWQIENHSQLFTPLAGKKVLGVKNEARKTAE ESLSTLCTAIKDYADTIKQVRESIVLHNQEQQKHHQPLSEIDKKLQKQQSLSQSAKPLERSTVKQHKELT EASKQEERPPIRPRKAETSKTMALS |
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Nucleotide Sequence: 1968 bp [Download] |
>gi|163867306|ref|NC_010161.1|:1821138-1823105 Bartonella tribocorum CIP 105476 chromosome, complete genome ATGAAAAAAAGAAACCCCTCCCCTTTAATAGCCGAAATGATGGCAAAATTTCAACAACAGGCTGAACAAT CTCCCACCAGTCCCTCCCATTCCCAAGTTTCTCAAAGTGTGCCAAAACCACCTGTACAAAAACGCCCAGA GAATTTGTCACATCCCCCAAAGGTTGCGCCACCGCCCCCCCTACGTATGAGAGATAAAACACCAGCTGAT ACAAAAATCCAAAAGCCTGAAACCCAAGAAAGCTCCTCCGCGCACATAAAAACGCCTCCACAAAGACCTC CACGTGCAAAAGATAGAGAACAAAACAAACAAACGGCTCAAGAATCCCCCTCTCTACAGACAAAAATGGC TCCGCCCAAACCTCCACGCATAAAAGATAAAACACCAGCCGACACAAAAATCCAAAAGCCTGAAACCCAA GAAAGCTCCTCCGCGCACATAAAAACGCCTCCACAAAGACCTCCACGTGCGAAGGATAGAGAACAAAACA AACAAACGGCTCAAGAATCCCCCTCTCTACAGACAAAAATGGCTCCGCCCAAACCTCCACGCATAAAAGA TAAAACACCAGCCGACACAAAAATCCAAAAGCCTGAAACCCAAGAAAGCTCCTCCGCACACATAAAAACG CCTCCACCAAAACCTCCACGTGCAAAAGATAGAGAACAAAACAAACAAACGGCTCAAGAATCCCCCTCTC TACAGACAAAAATGCCTCCGCCCACCCCCCCACGCATAAAAGATAAAACACCAGCCAACGCAACAATCCA AGTGCAAACCAGCACAAAAAACCAAAATCTAGAAACCATTGCTCCAAGTGTTAGACCCAAAACACCACAG CACAGGCAAGTCAGGCAGCAAAGCAGTTCATCATCACAAAACAGTGAGTCATATGCAGTACCTCCTTCAA GAAAACCACACCAAATAGGAGACAGACAAAAAAGTGAGGCTGCCATCCAAAAAACAGCAATTAGACAACC AAAACCGTCTCAGGAGCGTAAAGCATCTATTAATACAATGGAAAAAAAGCTATTGCTCGAAGCATACCAT GAAGAAATACGATTTTTATGTAAAAAGACTTTTGGTGACCGACTCATTTTAGAATCAAGAATAGAAGCCA TCAAAGAAAACCCCAATATGGGAGAACAACTCTTATGGGATGTTACAAAAAAACCTCAGTCTATTTCTAA GCTTGCTGGTAGAAAAGTTCTTGGCATAAAAAATGGAGCGCGCAAACAAGCTGAAGAAACGCTTTCCCCC CTATATGCTGCCATAGAAGGCTTTGTATATACTGCAAAATATGTACAAGAGAATACTTCACAAAATTCTC ACACAAAACAACAACAGCATCAACAAGCGCAACAGGAAGGAGCAATTAGTCAACACGCACGAAATCCTCT CCATTCAGAAAAGAAAATCCAGCCTCTCTCAAATCAAGAAATTGCCCGCAGAGTTCAACAAAACCCATCG GTTCAATATGGTCAAAGAGAAGTCCAATATTGGTGTCAAAAAGTTTATAGAGACCCATTTATTTTTAACG ACAGAATGGAAGATATGCAAAAAATTCCAGAGATAGGAGAAGAGCTCGTATGGCAAATTGAAAACCATTC TCAGCTTTTTACTCCACTTGCTGGTAAAAAAGTCCTTGGTGTAAAAAACGAAGCACGCAAAACTGCTGAA GAAAGTCTTTCCACCCTTTGTACCGCCATTAAGGATTATGCAGACACTATAAAACAGGTAAGAGAAAGTA TCGTGCTGCACAATCAAGAACAACAAAAACACCATCAGCCTCTTAGCGAAATAGATAAAAAATTACAAAA ACAGCAAAGCCTATCGCAGTCCGCAAAACCACTTGAACGCTCAACAGTAAAGCAGCATAAAGAGCTTACT GAAGCATCGAAACAAGAAGAGCGACCGCCTATTCGACCACGCAAAGCCGAAACATCAAAAACAATGGCTT TATCCTGA |
Reference |
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] |
experimental literature |