SecReT4
Effector Protein ID: 163868791
T4SS name [ID]VirB [225]
Gene symbolbepF
Locus tagBtr_1709
StrainBartonella tribocorum CIP 105476
Repliconchromosome [GenBank: NC_010161] [Browse all T4SS(s) in this replicon]
Location [Strand]1821138..1823105 [+]
Producthypothetical protein
Effector typeProtein
DescriptonBepF
T4CP requirementT4CP Depedent
Target/EffectionHomologous to BepF protein of Bartonella henselae. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells.
UniProt IDA9IWQ4
KEGG IDbtr:Btr_1709
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 655 a.a.     [Download]
>gi|163868791|ref|YP_001610015.1| hypothetical protein Btr_1709 [Bartonella tribocorum CIP 105476]
MKKRNPSPLIAEMMAKFQQQAEQSPTSPSHSQVSQSVPKPPVQKRPENLSHPPKVAPPPPLRMRDKTPAD
TKIQKPETQESSSAHIKTPPQRPPRAKDREQNKQTAQESPSLQTKMAPPKPPRIKDKTPADTKIQKPETQ
ESSSAHIKTPPQRPPRAKDREQNKQTAQESPSLQTKMAPPKPPRIKDKTPADTKIQKPETQESSSAHIKT
PPPKPPRAKDREQNKQTAQESPSLQTKMPPPTPPRIKDKTPANATIQVQTSTKNQNLETIAPSVRPKTPQ
HRQVRQQSSSSSQNSESYAVPPSRKPHQIGDRQKSEAAIQKTAIRQPKPSQERKASINTMEKKLLLEAYH
EEIRFLCKKTFGDRLILESRIEAIKENPNMGEQLLWDVTKKPQSISKLAGRKVLGIKNGARKQAEETLSP
LYAAIEGFVYTAKYVQENTSQNSHTKQQQHQQAQQEGAISQHARNPLHSEKKIQPLSNQEIARRVQQNPS
VQYGQREVQYWCQKVYRDPFIFNDRMEDMQKIPEIGEELVWQIENHSQLFTPLAGKKVLGVKNEARKTAE
ESLSTLCTAIKDYADTIKQVRESIVLHNQEQQKHHQPLSEIDKKLQKQQSLSQSAKPLERSTVKQHKELT
EASKQEERPPIRPRKAETSKTMALS
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Nucleotide Sequence: 1968 bp     [Download]
>gi|163867306|ref|NC_010161.1|:1821138-1823105 Bartonella tribocorum CIP 105476 chromosome, complete genome
ATGAAAAAAAGAAACCCCTCCCCTTTAATAGCCGAAATGATGGCAAAATTTCAACAACAGGCTGAACAAT
CTCCCACCAGTCCCTCCCATTCCCAAGTTTCTCAAAGTGTGCCAAAACCACCTGTACAAAAACGCCCAGA
GAATTTGTCACATCCCCCAAAGGTTGCGCCACCGCCCCCCCTACGTATGAGAGATAAAACACCAGCTGAT
ACAAAAATCCAAAAGCCTGAAACCCAAGAAAGCTCCTCCGCGCACATAAAAACGCCTCCACAAAGACCTC
CACGTGCAAAAGATAGAGAACAAAACAAACAAACGGCTCAAGAATCCCCCTCTCTACAGACAAAAATGGC
TCCGCCCAAACCTCCACGCATAAAAGATAAAACACCAGCCGACACAAAAATCCAAAAGCCTGAAACCCAA
GAAAGCTCCTCCGCGCACATAAAAACGCCTCCACAAAGACCTCCACGTGCGAAGGATAGAGAACAAAACA
AACAAACGGCTCAAGAATCCCCCTCTCTACAGACAAAAATGGCTCCGCCCAAACCTCCACGCATAAAAGA
TAAAACACCAGCCGACACAAAAATCCAAAAGCCTGAAACCCAAGAAAGCTCCTCCGCACACATAAAAACG
CCTCCACCAAAACCTCCACGTGCAAAAGATAGAGAACAAAACAAACAAACGGCTCAAGAATCCCCCTCTC
TACAGACAAAAATGCCTCCGCCCACCCCCCCACGCATAAAAGATAAAACACCAGCCAACGCAACAATCCA
AGTGCAAACCAGCACAAAAAACCAAAATCTAGAAACCATTGCTCCAAGTGTTAGACCCAAAACACCACAG
CACAGGCAAGTCAGGCAGCAAAGCAGTTCATCATCACAAAACAGTGAGTCATATGCAGTACCTCCTTCAA
GAAAACCACACCAAATAGGAGACAGACAAAAAAGTGAGGCTGCCATCCAAAAAACAGCAATTAGACAACC
AAAACCGTCTCAGGAGCGTAAAGCATCTATTAATACAATGGAAAAAAAGCTATTGCTCGAAGCATACCAT
GAAGAAATACGATTTTTATGTAAAAAGACTTTTGGTGACCGACTCATTTTAGAATCAAGAATAGAAGCCA
TCAAAGAAAACCCCAATATGGGAGAACAACTCTTATGGGATGTTACAAAAAAACCTCAGTCTATTTCTAA
GCTTGCTGGTAGAAAAGTTCTTGGCATAAAAAATGGAGCGCGCAAACAAGCTGAAGAAACGCTTTCCCCC
CTATATGCTGCCATAGAAGGCTTTGTATATACTGCAAAATATGTACAAGAGAATACTTCACAAAATTCTC
ACACAAAACAACAACAGCATCAACAAGCGCAACAGGAAGGAGCAATTAGTCAACACGCACGAAATCCTCT
CCATTCAGAAAAGAAAATCCAGCCTCTCTCAAATCAAGAAATTGCCCGCAGAGTTCAACAAAACCCATCG
GTTCAATATGGTCAAAGAGAAGTCCAATATTGGTGTCAAAAAGTTTATAGAGACCCATTTATTTTTAACG
ACAGAATGGAAGATATGCAAAAAATTCCAGAGATAGGAGAAGAGCTCGTATGGCAAATTGAAAACCATTC
TCAGCTTTTTACTCCACTTGCTGGTAAAAAAGTCCTTGGTGTAAAAAACGAAGCACGCAAAACTGCTGAA
GAAAGTCTTTCCACCCTTTGTACCGCCATTAAGGATTATGCAGACACTATAAAACAGGTAAGAGAAAGTA
TCGTGCTGCACAATCAAGAACAACAAAAACACCATCAGCCTCTTAGCGAAATAGATAAAAAATTACAAAA
ACAGCAAAGCCTATCGCAGTCCGCAAAACCACTTGAACGCTCAACAGTAAAGCAGCATAAAGAGCTTACT
GAAGCATCGAAACAAGAAGAGCGACCGCCTATTCGACCACGCAAAGCCGAAACATCAAAAACAATGGCTT
TATCCTGA

Reference
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] experimental
 
experimental experimental literature