| Effector Protein ID: 163868789 |
 T4SS name [ID] | VirB [225] |
| Gene symbol | bepH |
| Locus tag | Btr_1706 |
| Strain | Bartonella tribocorum CIP 105476 |
| Replicon | chromosome [GenBank: NC_010161] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1818370..1819188 [+] |
| Product | BepH protein |
| Effector type | Protein |
| Descripton | BepH |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Homologous to BepE. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. |
| UniProt ID | A9IWQ0 |
| KEGG ID | btr:Btr_1706 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 272 a.a. [Download] |
| >gi|163868789|ref|YP_001610013.1| BepH protein [Bartonella tribocorum CIP 105476] MKKHHPHPEPLYAQVNKQNRGNQRTQNPEEDVLYASVSEVSPLSRGRRPDRKSGGTETDYTEVAPPKREE EILYASVSTSSPLSRGRHHTQRNEGPETDYTEVSPHQKGRSSSPSLTTDQKSVMLLKNPQVQARAEEVIH WSKIVYGDDTIFQKHLQSILTDPNKGKELSDQLAEDPESIHRLAGRSALGLKSQTRRAAEDGFKPLVDAI DDYTKTVEDATKRLSQTPLAEQKRHHHHHHHHRHHERGLNQESPEHSPQRQRHGDKGMAYAM |
| - |
| Nucleotide Sequence: 819 bp [Download] |
| >gi|163867306|ref|NC_010161.1|:1818370-1819188 Bartonella tribocorum CIP 105476 chromosome, complete genome ATGAAAAAACATCATCCACACCCAGAGCCCCTCTATGCACAAGTTAATAAACAAAACAGAGGAAACCAGC GCACCCAAAACCCAGAAGAGGACGTTCTATATGCATCTGTTAGCGAGGTCTCCCCTCTTTCAAGAGGGAG GCGTCCTGATCGGAAAAGTGGGGGGACTGAAACTGATTACACAGAGGTTGCTCCCCCAAAACGTGAAGAG GAAATTCTATACGCATCAGTGAGCACCTCCTCCCCTCTTTCAAGAGGTAGACACCATACTCAAAGGAATG AAGGTCCTGAAACAGACTATACAGAGGTCTCTCCGCACCAAAAAGGAAGATCATCTTCACCTTCTCTCAC AACTGACCAAAAGAGTGTAATGCTTTTAAAAAATCCGCAGGTCCAAGCACGTGCAGAAGAGGTCATACAT TGGAGTAAAATTGTTTATGGCGATGATACAATTTTCCAAAAACATTTGCAAAGCATACTTACAGATCCCA ATAAAGGAAAAGAGCTTTCAGATCAACTTGCTGAAGATCCTGAATCTATACATAGGCTTGCTGGCCGCTC CGCACTTGGACTAAAAAGTCAAACACGCAGAGCAGCTGAAGACGGTTTTAAACCGCTTGTTGACGCCATT GATGATTATACAAAGACTGTAGAAGACGCAACAAAGAGGCTATCGCAAACCCCTCTAGCGGAACAAAAAC GTCATCACCATCACCACCATCATCATCGTCATCACGAAAGGGGACTAAACCAAGAGAGTCCAGAACACAG CCCTCAACGACAAAGACATGGAGACAAAGGAATGGCTTATGCCATGTAA |
| Reference |
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] 
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| experimental literature |