| Effector Protein ID: 163868785 |
 T4SS name [ID] | VirB [225] |
| Gene symbol | bepA |
| Locus tag | Btr_1700 |
| Strain | Bartonella tribocorum CIP 105476 |
| Replicon | chromosome [GenBank: NC_010161] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1809235..1810869 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | BepA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Homologous to BepA protein of Bartonella henselae, putative cell filamentation protein. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. |
| UniProt ID | A9IWP4 |
| KEGG ID | btr:Btr_1700 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Fic [PF02661], Evalue: 1.7e-10, Aligned region: 63..175 |
| Protein Sequence: 544 a.a. [Download] |
| >gi|163868785|ref|YP_001610009.1| hypothetical protein Btr_1700 [Bartonella tribocorum CIP 105476] MPKAKEKTKNIETSSPHHYVYPNTTTLKNKYGITNFDAFTAKYTHDTAKAIVNLREAPLPEKFDSSYLCS IHHQLFKNTFEWAGQPRNVPFTFLDESVTAMPEMKRAEWNNVFANDDEIEEGLQTLNKTLAEKNALRSLT REDFISEAVPLFVSLKNIRPFINGNEHTIHLFFEKLAQAAEHQLDFSLVTKERMLVASVAAIQNDNLEPM QHLFEDISNPQKIHLLKEFMSNMKELGRDINDRSVMVTKEGETYTGTYRGAGHDSLAFNVNGAYIIGDKE DLTPEQLKTLKPGDKFTFTASQTQELKNILIPKETLAPLSKTEKAEMIAKDACVHTARNQIQRLSKTVYD NAKTLDKKMVAIIKNPALGQQLAEQIERSPDSVAHLAGFSLCGLQNQARANAKNHLEMLCSAVANFAHAV KHAEKEITQEHATEQKRRATTVEMPSKSLQDLFTLPKELQQESLAKNLGLQKELSNLVKNINSRLSATEH KAVKNNDYETLAQSIGVSENKAKQITQTVKQAKEVHQQACTRTVNHSNVLAIAS |
| - |
| Nucleotide Sequence: 1635 bp [Download] |
| >gi|163867306|ref|NC_010161.1|:1809235-1810869 Bartonella tribocorum CIP 105476 chromosome, complete genome ATGCCAAAAGCCAAAGAAAAAACCAAAAATATAGAGACATCTTCTCCTCATCATTATGTCTATCCGAACA CCACAACACTCAAAAATAAATATGGAATAACAAACTTTGACGCTTTTACTGCAAAATATACGCATGATAC AGCAAAAGCCATAGTTAACCTGCGTGAAGCCCCCCTACCAGAAAAATTTGATAGCTCCTATCTATGCTCT ATTCACCATCAATTGTTTAAAAATACCTTTGAATGGGCAGGACAGCCCCGCAATGTTCCCTTTACATTTT TAGACGAAAGCGTTACCGCCATGCCAGAGATGAAAAGGGCGGAATGGAACAATGTTTTTGCGAATGATGA TGAGATTGAAGAAGGTTTACAAACATTAAATAAAACACTTGCAGAAAAAAACGCTTTGAGAAGCTTAACG CGCGAAGATTTTATTTCAGAAGCCGTACCACTCTTTGTCTCTCTCAAAAATATACGTCCATTCATAAATG GGAATGAACATACAATACACCTCTTTTTTGAAAAGCTTGCTCAAGCAGCAGAGCATCAGCTTGATTTTTC ACTTGTTACAAAAGAACGCATGCTGGTTGCTAGTGTTGCAGCAATACAAAATGACAATCTAGAACCGATG CAACATCTGTTTGAAGATATCTCCAATCCCCAAAAAATTCATCTTTTAAAAGAATTCATGAGCAATATGA AAGAACTTGGACGCGATATTAATGATCGTTCTGTTATGGTCACAAAGGAAGGTGAAACTTACACGGGCAC CTATAGGGGGGCTGGTCATGATAGCCTTGCTTTCAATGTGAATGGCGCTTACATCATCGGTGATAAAGAA GATCTCACACCAGAACAACTCAAAACATTAAAGCCTGGTGATAAATTTACCTTCACTGCCTCACAAACCC AAGAGTTAAAAAATATTCTCATTCCTAAAGAAACATTAGCGCCTTTATCAAAAACTGAAAAAGCTGAAAT GATTGCAAAAGATGCCTGTGTCCACACCGCTCGAAACCAAATCCAACGATTGTCAAAAACTGTTTATGAC AACGCAAAAACATTAGACAAAAAGATGGTTGCGATTATTAAAAATCCAGCCTTAGGTCAGCAACTTGCAG AGCAGATTGAGAGGTCACCCGACTCTGTTGCTCATCTTGCCGGTTTCAGTTTATGTGGACTCCAAAATCA GGCACGTGCAAACGCTAAAAATCATCTTGAGATGCTCTGTAGTGCTGTTGCAAATTTCGCGCATGCTGTC AAACATGCGGAGAAAGAAATTACGCAAGAACATGCAACAGAACAGAAACGCCGTGCAACCACAGTAGAAA TGCCCAGTAAAAGCTTGCAAGATCTCTTCACCTTGCCAAAAGAATTACAGCAAGAATCTTTAGCAAAAAA TCTTGGACTTCAAAAAGAGCTGAGCAATCTTGTAAAAAACATCAATAGCCGCCTCTCAGCAACTGAACAT AAAGCTGTCAAAAATAATGATTACGAAACATTGGCTCAAAGTATTGGTGTCTCAGAAAATAAAGCCAAGC AAATTACACAAACCGTTAAGCAAGCCAAAGAAGTACACCAGCAAGCCTGCACGCGCACAGTTAACCATTC AAATGTACTCGCTATAGCCAGCTAA |
| Reference |
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] 
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| experimental literature |