| Effector Protein ID: 154707650 |
 T4SS name [ID] | Dot/Icm [160] |
| Gene symbol | - |
| Locus tag | CBUD_1627 |
| Strain | Coxiella burnetii Dugway 5J108-111 |
| Replicon | chromosome [GenBank: NC_009727] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1627582..1628136 [+] |
| Product | ankyrin repeat protein |
| Effector type | Protein |
| Descripton | AnkF |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Inhibits apoptosis |
| UniProt ID | A9KEE4 |
| KEGG ID | cbd:CBUD_1627 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Ank_2 [PF12796], Evalue: 9.2e-19, Aligned region: 17..95 Ank_2 [PF12796], Evalue: 9.2e-19, Aligned region: 113..169 Ank [PF00023], Evalue: 2.6e-16, Aligned region: 74..95 Ank_5 [PF13857], Evalue: 6.5e-16, Aligned region: 71..94 Ank_4 [PF13637], Evalue: 5.5e-14, Aligned region: 45..94 |
| Protein Sequence: 184 a.a. [Download] |
| >gi|154707650|ref|YP_001424964.1| ankyrin repeat protein [Coxiella burnetii Dugway 5J108-111] MRQREINDEAMQRLFEACIYNAPGEMERILQRTDIDPNQKYEDKTPLEIASLEGYRDIVELLIEHPLVVD SREGYQALHFACERGHVEIAELLLGKVVQRRGRVASKLLANLLYTACESGKLEIVKLLIEGYARDPFIAL ERTEYGIPLAIAAARNFQPIVDYFWEQGVPYLEEEKRNNRGFQR |
| - |
| Nucleotide Sequence: 555 bp [Download] |
| >gi|154705721|ref|NC_009727.1|:1627582-1628136 Coxiella burnetii Dugway 5J108-111 chromosome, complete genome ATGAGACAGCGTGAAATTAATGATGAAGCTATGCAGCGGCTATTTGAAGCTTGTATCTATAATGCCCCCG GCGAGATGGAAAGGATATTGCAAAGGACGGACATTGATCCCAATCAAAAATATGAAGATAAAACACCACT CGAAATCGCTTCCTTGGAAGGTTATCGAGATATTGTGGAACTTTTAATTGAACACCCTCTCGTAGTCGAC TCAAGAGAGGGGTATCAAGCACTCCATTTCGCTTGTGAGCGTGGTCACGTAGAGATAGCAGAACTTTTAT TGGGTAAGGTAGTACAGCGGCGTGGGCGAGTTGCTTCAAAGCTATTGGCCAACCTTCTATACACCGCCTG CGAATCAGGAAAGCTTGAAATTGTAAAACTATTAATTGAGGGATACGCTAGAGATCCCTTTATTGCTTTA GAGCGGACCGAATACGGCATCCCTCTGGCCATTGCAGCCGCCCGCAACTTTCAACCTATCGTCGATTACT TTTGGGAACAAGGCGTACCTTATCTGGAAGAAGAAAAAAGAAATAATCGCGGCTTCCAGCGGTAG |
| Reference |
| (1) McDonough JA; Newton HJ; Roy CR (2012). Coxiella burnetii Secretion Systems. Adv Exp Med Biol. 984:171-97. [PudMed:22711632] |
(2) Voth DE; Howe D; Beare PA; Vogel JP; Unsworth N; Samuel JE; Heinzen RA (2009). The Coxiella burnetii ankyrin repeat domain-containing protein family is heterogeneous, with C-terminal truncations that influence Dot/Icm-mediated secretion. J Bacteriol. 191(13):4232-42. [PudMed:19411324] 
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(3) Pan X; Luhrmann A; Satoh A; Laskowski-Arce MA; Roy CR (2008). Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors. Science. 320(5883):1651-4. [PudMed:18566289] 
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| experimental literature |
| in silico analysis literature |