| Effector Protein ID: 154707569 |
 T4SS name [ID] | Dot/Icm [160] |
| Gene symbol | - |
| Locus tag | CBUD_1298 |
| Strain | Coxiella burnetii Dugway 5J108-111 |
| Replicon | chromosome [GenBank: NC_009727] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1288705..1290885 [+] |
| Product | ankyrin repeat protein |
| Effector type | Protein |
| Descripton | AnkI |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Predicted effector. Homologous to AnkI. Function unknown. |
| UniProt ID | A9KFR3 |
| KEGG ID | cbd:CBUD_1298 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Ank_2 [PF12796], Evalue: 5.2e-18, Aligned region: 371..436 Ank_2 [PF12796], Evalue: 5.2e-18, Aligned region: 380..460 Ank_2 [PF12796], Evalue: 5.2e-18, Aligned region: 448..516 Ank_4 [PF13637], Evalue: 1.5e-11, Aligned region: 377..434 Ank_4 [PF13637], Evalue: 1.5e-11, Aligned region: 416..458 Ank_5 [PF13857], Evalue: 7.2e-09, Aligned region: 403..457 |
| Protein Sequence: 726 a.a. [Download] |
| >gi|154707569|ref|YP_001424652.1| ankyrin repeat protein [Coxiella burnetii Dugway 5J108-111] MRESSENQKRESLKNQKKVFYSYLRDEFGLKPYIQLPVHYIAYCGQMKDVIRVLQMAKNRLKPETFQSLL KDTRHTDKVTGTVYAHFYYNAVRNINIWKVDNIIKVLNLFKYEDDNTLQNKENVILAYIYLTLSRNDVSL LEECINKFKTAFPITTIHALKFGCFDDKMRLSAYALQKGASLAIAYFKFTPLALAEYLNTRASRKDAIET WVSLMREGLLLLDNLTAILKDLKGEILKIIPQVINLIYPLIDSPEEKEEKQPEKHATLKDYCNVLISTYN DLDRSTFLGNSDTSNEQKFQLIAAQFLYSEDKDSKCLNEVTDNLSLKKRIHQPLNSSGLLLLNELIRKNK HRTVYSLVSPDSAVRVANPDEKDVTKRSALHWAVEKSDDSVEWLKTIQLLLHQMTTQADHDKEGETAVHI AARTQKPKTLKLLLQHFRCRESILIKNNKGETPLHIAAVTKTDDSGTIIRLLAEQPDTQCNLEERNWNGN TAFLVACTENNTSAVFELMSLGCDQDTCGRHGQRVYKNLINSNHSSYNEAFVNKLEELRNNSASRNSKFT SFAPSAPSFPLNQPRQNHEEGEEGLTLEQKGETKEEQNHGHEADEMAKRLALFKCKVTRLLQIRQAQTCT VIVGGESISGVHSPAFKKELGGIIDTIWECTSIEAIKDYLSEESQKTAISKCRKLSQWNAFWGKKQSTTW KSLEKLFVNFPSASSQNTSEPGSFGI |
| - |
| Nucleotide Sequence: 2181 bp [Download] |
| >gi|154705721|ref|NC_009727.1|:1288705-1290885 Coxiella burnetii Dugway 5J108-111 chromosome, complete genome ATGAGAGAATCATCAGAAAATCAAAAAAGAGAATCATTAAAAAATCAAAAAAAGGTATTTTATAGTTACC TAAGGGATGAGTTTGGCCTGAAGCCATACATCCAACTTCCAGTACATTACATTGCTTATTGTGGTCAGAT GAAGGATGTGATACGAGTATTGCAAATGGCTAAAAACAGGCTCAAGCCAGAAACATTTCAGTCATTACTC AAAGACACGCGCCACACGGATAAAGTTACCGGAACGGTTTATGCACACTTTTACTATAATGCAGTTCGTA ATATTAATATCTGGAAAGTTGACAATATCATCAAAGTGTTAAATCTATTTAAATACGAAGATGACAACAC ATTGCAAAATAAAGAAAACGTAATTCTAGCTTATATCTATTTGACCCTCTCTCGAAATGATGTATCTTTA TTAGAAGAATGTATTAACAAGTTTAAGACCGCTTTCCCTATAACCACTATTCACGCACTGAAGTTCGGCT GCTTTGATGATAAGATGAGGTTATCTGCCTATGCCCTCCAAAAGGGGGCGTCATTGGCAATTGCTTATTT TAAATTTACGCCTTTGGCTTTAGCAGAATATCTTAATACGCGGGCTTCTCGTAAAGACGCCATCGAAACA TGGGTTTCCCTCATGAGAGAAGGATTACTACTTTTGGATAATTTGACTGCTATTTTGAAGGATCTAAAGG GAGAAATTTTAAAAATTATCCCTCAAGTGATTAATCTCATCTATCCACTCATTGATTCGCCAGAAGAAAA AGAGGAAAAACAACCAGAGAAGCACGCAACGCTGAAAGATTATTGCAATGTTCTTATATCAACATATAAC GATCTTGACCGTTCAACTTTCCTAGGGAATTCTGACACATCAAATGAGCAAAAATTTCAGCTCATTGCGG CTCAGTTTCTATATTCAGAAGATAAAGACTCAAAATGTCTTAACGAGGTTACTGATAACCTTAGCTTGAA AAAAAGAATACATCAGCCCCTGAATTCCAGCGGTTTATTGTTATTGAATGAATTGATTAGGAAAAATAAA CATCGCACCGTTTATAGTTTGGTATCCCCAGATTCCGCTGTGCGGGTTGCTAATCCCGATGAAAAGGATG TCACTAAACGATCCGCTTTACATTGGGCAGTTGAAAAAAGCGACGACAGCGTGGAATGGCTTAAAACGAT TCAGCTATTACTTCATCAAATGACAACACAGGCCGATCACGATAAAGAAGGTGAAACAGCCGTGCATATC GCCGCGCGCACTCAAAAACCAAAAACGCTAAAGTTATTACTTCAGCATTTTCGTTGTCGAGAATCAATTT TGATAAAAAACAATAAAGGTGAGACCCCCTTACACATTGCAGCCGTCACGAAAACGGATGATAGTGGTAC CATTATTCGCTTATTAGCAGAACAACCCGATACCCAATGTAATCTAGAAGAACGAAATTGGAACGGTAAT ACCGCATTCTTGGTAGCGTGTACGGAAAACAATACAAGCGCCGTTTTTGAATTAATGAGCTTGGGATGCG ATCAGGATACTTGTGGTCGTCATGGACAGCGTGTCTATAAAAATCTGATAAATTCCAATCACTCCTCTTA TAACGAAGCCTTTGTAAATAAACTTGAAGAGTTACGTAACAATTCCGCTTCAAGGAATAGTAAGTTCACT TCCTTTGCGCCATCGGCGCCTTCGTTCCCGCTCAACCAGCCCAGGCAAAATCATGAAGAAGGAGAAGAAG GTCTTACCTTAGAGCAAAAGGGTGAAACGAAAGAAGAACAAAATCATGGCCACGAAGCCGACGAGATGGC TAAGCGGTTGGCTTTATTTAAATGTAAAGTCACCCGCCTACTGCAAATTCGGCAAGCGCAAACTTGTACT GTTATTGTGGGTGGCGAATCAATATCAGGAGTTCATAGCCCCGCCTTCAAGAAAGAGCTTGGGGGTATTA TTGATACCATTTGGGAGTGTACCTCCATTGAAGCAATAAAAGACTATCTATCAGAAGAAAGCCAAAAAAC AGCGATTAGTAAATGTAGGAAACTCTCACAATGGAACGCATTTTGGGGAAAAAAACAAAGTACTACTTGG AAAAGCTTAGAAAAGTTATTCGTCAACTTTCCGAGCGCCTCATCCCAAAATACATCAGAGCCGGGTTCTT TTGGAATTTAG |
| Reference |
| (1) McDonough JA; Newton HJ; Roy CR (2012). Coxiella burnetii Secretion Systems. Adv Exp Med Biol. 984:171-97. [PudMed:22711632] |
(2) Voth DE; Howe D; Beare PA; Vogel JP; Unsworth N; Samuel JE; Heinzen RA (2009). The Coxiella burnetii ankyrin repeat domain-containing protein family is heterogeneous, with C-terminal truncations that influence Dot/Icm-mediated secretion. J Bacteriol. 191(13):4232-42. [PudMed:19411324] 
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(3) Zusman T; Aloni G; Halperin E; Kotzer H; Degtyar E; Feldman M; Segal G (2007). The response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii. Mol Microbiol. 63(5):1508-23. [PudMed:17302824]
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| experimental literature |