| Effector Protein ID: 148360036 |
 T4SS name [ID] | Dot/Icm [42] |
| Gene symbol | - |
| Locus tag | LPC_1967 |
| Strain | Legionella pneumophila str. Corby |
| Replicon | chromosome [GenBank: NC_009494] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2998996..3001824 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | SidI/ceg32 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | SidI interacts with eEF1A and eEF1Bgamma and inhibits protein synthesis. SidI is also involved in a stress response of eukaryotic cell (Belyi, et al. 2011) |
| UniProt ID | A5IEU7 |
| KEGG ID | lpc:LPC_1967 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 942 a.a. [Download] |
| >gi|148360036|ref|YP_001251243.1| hypothetical protein LPC_1967 [Legionella pneumophila str. Corby] MTKIYLLTAPFDEEAKTGDGQYAASLELGFAENYEHIPCKWLKKDKGDYSIPFPTGTTSIPEETIPSAMV LQPVANENTIISGYKLKDAVSSPEKAQEVNNKTVSPRTPKIIVKHDNSLQSLTIMDIYSQKAIQFDESKV DEIINSLETKKDKLEKAIEDNNVDLSKIKKQKSKLAYLTRLYKENKENIQDNCTLNEYIEAHLFNPKFLS RHEKALNNFKALKSQFTGPVNLKELEKLTDKLTGIKEYSYDFHSNSLPYDLEHDKSFRNFYDFDGLKESI ENIIKELEVLNGIRQAVSDKYPNCFKALNETEEHDDKLKFINIIFNDGFSTTYDQQTFIKALSALDVEKA IDAYTNVKKKLENTQDIIANKEGGRNKLISELQTLIANKQEPYLSANEKLGGFYSKRKLSASEGFHLAYQ ANRRDPIKPEVIENIITKMKPIDEDTHLDIHIRPPDCGVFITPEDIKKFQEAGIKVNITIHEYKQNYTRR YLQQYTHDLMRQANSVQFFNATDRENAIIAATYGDCDKRNTTEPTGVAKKIREVGEDFDLDKYPVQKYDL KGKSGLTVASQKLSTEPDHPLDVVAKAPNILSFGTIRPGKGFEEALKLAQLIKDNSLSIDEKIKRVPIVK LAGDPQDKALMKQIVIERFGKTAVKTYQKTHPYDNQFNNSQRRDYWKNLVRELNAKVKEEGAVLNNPYIE IYPWCEPHELLALKQNCKYVCRMDDMGMRNNGSAIISVLDVGVVYTKFGSVTDDIFIKGGKYGNAVDIGE YRYGKYSLLKKEKEFKEQHEEEPLPKWLIKNPDSAYKRQSESRDPKDILDSIVAREENQLICDNIEDSDN YRTVVEAQKLLKERFTLKNAVDHLLENIGLGHLIAQEEVDELFETVDPVQAQIDNLDVLSDIKTPRLCLS RSCPELGFFGSRRGDLETKQENNKLKESILVF |
| - |
| Nucleotide Sequence: 2829 bp [Download] |
| >gi|295815281|ref|NC_009494.2|:2998996-3001824 Legionella pneumophila str. Corby chromosome, complete genome ATGACTAAAATATACTTATTAACCGCACCTTTTGATGAAGAGGCAAAAACAGGTGATGGGCAATACGCGG CCTCTTTAGAATTGGGTTTTGCTGAAAATTACGAACATATCCCCTGTAAATGGTTAAAAAAAGATAAAGG TGATTACAGTATTCCATTCCCAACAGGAACTACTTCCATACCGGAAGAAACGATACCAAGCGCGATGGTA TTACAGCCAGTTGCTAACGAAAATACCATCATAAGCGGTTATAAATTAAAAGATGCTGTTTCGTCTCCAG AAAAAGCACAGGAAGTAAATAACAAAACGGTTAGTCCCAGAACGCCCAAAATTATTGTAAAGCATGATAA CAGCCTGCAATCACTTACAATAATGGATATTTACTCTCAAAAAGCTATCCAATTTGATGAGTCAAAAGTT GATGAAATAATTAACTCTTTAGAAACAAAAAAAGATAAACTGGAAAAAGCTATAGAAGATAATAACGTTG ATCTGAGTAAAATTAAGAAACAAAAATCCAAATTAGCGTATCTGACTAGATTATATAAAGAAAACAAAGA GAATATTCAAGATAATTGCACCTTAAATGAATATATTGAGGCACATTTATTTAATCCTAAATTTTTAAGC AGGCATGAGAAAGCACTTAATAATTTTAAGGCGCTTAAAAGCCAATTTACTGGCCCTGTCAATTTAAAAG AACTGGAAAAATTAACAGATAAACTGACTGGAATTAAAGAGTACAGCTATGATTTCCATAGTAACAGTTT ACCCTATGATTTAGAGCACGATAAAAGTTTCAGAAATTTTTATGATTTTGATGGATTAAAAGAATCTATT GAAAACATTATCAAGGAATTAGAGGTACTTAACGGCATTCGTCAGGCTGTATCAGACAAGTATCCCAATT GCTTTAAAGCGCTAAATGAAACAGAAGAGCACGACGATAAATTAAAATTTATCAATATTATTTTCAACGA TGGGTTTAGCACCACTTATGACCAACAAACCTTTATCAAGGCCTTATCAGCTCTTGATGTTGAAAAGGCA ATTGACGCTTATACAAATGTTAAAAAGAAACTGGAAAACACTCAGGATATTATCGCCAATAAAGAGGGGG GTAGAAATAAGTTAATTTCAGAATTACAAACTTTAATAGCAAATAAACAAGAACCTTACCTCTCTGCAAA TGAAAAGCTTGGCGGTTTTTACAGTAAAAGAAAACTCTCTGCAAGTGAAGGATTTCATTTAGCCTATCAG GCAAACCGACGTGACCCGATAAAACCTGAAGTGATTGAAAACATTATTACCAAAATGAAACCCATTGATG AGGATACTCATCTTGATATTCATATTCGCCCACCAGATTGCGGGGTCTTTATTACTCCAGAAGACATCAA AAAATTTCAAGAGGCTGGTATTAAAGTCAATATCACAATCCATGAATATAAACAGAACTACACTCGGCGT TATTTACAACAATATACTCATGATTTAATGCGCCAGGCAAACAGCGTGCAATTCTTTAATGCAACAGATA GGGAAAATGCTATTATTGCCGCTACTTATGGTGATTGTGATAAGCGCAATACAACTGAACCGACTGGTGT TGCAAAAAAAATAAGAGAAGTTGGGGAAGATTTTGACTTAGATAAATACCCGGTTCAAAAATATGATTTA AAAGGAAAATCAGGATTAACCGTTGCATCACAAAAATTAAGTACCGAACCGGATCATCCATTGGATGTAG TAGCCAAGGCCCCTAATATCTTATCTTTTGGTACGATTCGTCCTGGCAAAGGGTTTGAAGAAGCGTTAAA GCTGGCTCAATTGATCAAAGATAACTCTCTTTCTATTGATGAAAAAATAAAACGGGTACCTATTGTAAAA CTGGCTGGTGACCCACAAGACAAAGCTTTAATGAAACAAATAGTTATTGAAAGGTTTGGTAAAACAGCGG TCAAAACTTATCAAAAAACTCATCCCTATGATAATCAATTCAATAATAGTCAGCGCAGAGATTATTGGAA AAATTTGGTTAGGGAGTTAAATGCAAAAGTTAAAGAAGAAGGCGCTGTTCTTAATAATCCTTACATCGAA ATTTATCCTTGGTGTGAGCCGCATGAATTGCTGGCTTTAAAGCAAAACTGTAAATACGTTTGTCGAATGG ACGACATGGGCATGAGAAACAATGGCTCAGCAATTATCAGTGTATTAGACGTTGGAGTCGTTTATACTAA ATTTGGTTCTGTTACAGACGATATTTTCATTAAGGGCGGCAAATACGGCAATGCCGTTGATATTGGAGAA TATCGTTATGGTAAATACAGTCTGTTAAAAAAAGAAAAGGAATTTAAAGAACAACATGAGGAAGAACCAC TACCTAAGTGGCTAATCAAAAATCCAGACTCTGCTTATAAGCGACAATCAGAATCGAGAGATCCAAAGGA TATTTTAGACTCCATTGTCGCAAGAGAAGAAAATCAATTAATATGTGATAATATAGAAGATTCCGATAAT TATCGAACAGTAGTCGAAGCACAAAAGTTATTAAAAGAGCGCTTTACACTCAAAAATGCTGTAGATCATT TATTAGAGAATATAGGACTCGGCCATTTAATTGCTCAAGAAGAAGTCGATGAATTATTTGAGACAGTTGA TCCAGTGCAAGCACAAATAGATAATTTAGACGTTCTTTCTGATATTAAGACACCACGTCTGTGTTTATCA CGCTCTTGCCCTGAGCTAGGTTTTTTCGGCTCACGTCGTGGTGACTTAGAGACTAAACAAGAAAATAATA AACTTAAAGAATCGATACTGGTATTTTGA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |