| Effector Protein ID: 148360028 |
 T4SS name [ID] | Dot/Icm [42] |
| Gene symbol | sidC |
| Locus tag | LPC_1959 |
| Strain | Legionella pneumophila str. Corby |
| Replicon | chromosome [GenBank: NC_009494] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 3012349..3015078 [+] |
| Product | Dot/Icm system substrate protein SidC |
| Effector type | Protein |
| Descripton | SidC |
| T4CP requirement | T4CP Depedent |
| Target/Effection | SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole. (Ragaz et al, 2008) |
| UniProt ID | A5IET9 |
| KEGG ID | lpc:LPC_1959 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 909 a.a. [Download] |
| >gi|148360028|ref|YP_001251235.1| Dot/Icm system substrate protein SidC [Legionella pneumophila str. Corby] MVDVIKFKEPERCDYLYIDENNKVHILLPIVGGDEIGLDNTCQTAVELITFFYGSAHSGVTKYSAEHQLS EYKRQLEEDIKAINSQKKISPHAYDDLLKEKKERLQQIEKYIELIQVLKGQNAEQDIRQLRTGGIPKLPA AVKEIIKSSENAFAVRLSPYDNDKFTRFDDPLFNVKRNISKYDTPSRQAPIPIYEGLGYRLRSTLFPKEK TPTPINKKSLREKVKSTVLSHYKEEDRIDGEKRDEKLSELITKLQNELVKELVKIDPQYSKLSLSKDPRG NEINYNYLVNSLMLVDDDSKIGEWIETILDSTVDSTVWEAQASSPFYDGAKEIKSDKEADRISIRVQYLL AEANIYCKTNKLSDANFGEFFDKEPHATEIAKRVKEGFTQGAEIEPIIYDYINNNHAELGLKSPLTGEQL QEITEKFTRHYNTIKESPHFDEFFVADPDKKGNIFCHQGRISCHFLDFFTRHTKGNYPLGDLANHQESLQ KGTSNRLHHKNELVAQGYERLDQFKKEVVKLLAEDKPKELLDYLLTNSPTGVPNYSMLSKETQNYIAYNR NWPAIQKELEQTTNIPENQKQDLLRLLSRDNLSHDNLSAITWSKYSSKPLLDVELNKIAEGLELTAKIYN EKRGSEWWFKGSRNQARNTQCEELQRVAKEINALLQNETLTKSQVLEKVLNSIETLDKIDRDISAESNWF KSTLQKEVRLFRDQLKDICQLDKYAFKSTKLDEIISLEMEEQFQKIEDPVVQKIVRDLPAHCHNDEAIEF FKTLNPEEAAKVASYLSLEYREINKSTDKKTLLEQDIPKLFKEVNALLLSKLKEEKAIDEQVHEKLSQLA DKIPPEHFTRNNIIKWSATPEKLEESNLNELIKSVESPTTKQTSKQFREAMGEITGRNEPPKDTLGHTI |
| - |
| Nucleotide Sequence: 2730 bp [Download] |
| >gi|295815281|ref|NC_009494.2|:3012349-3015078 Legionella pneumophila str. Corby chromosome, complete genome ATGGTTGACGTAATCAAATTCAAAGAGCCGGAACGTTGTGACTATCTATATATTGATGAAAACAACAAAG TTCATATCCTTTTACCGATTGTAGGAGGAGATGAAATAGGTCTGGATAACACCTGTCAAACAGCAGTTGA GTTGATCACATTTTTCTATGGTAGTGCGCACAGTGGTGTGACTAAATATTCTGCCGAACACCAACTCAGT GAATACAAAAGGCAATTGGAAGAAGACATCAAAGCCATCAATAGTCAAAAGAAAATTTCACCCCATGCTT ATGACGATTTATTAAAAGAGAAAAAAGAACGCCTGCAACAAATTGAAAAATACATTGAATTAATTCAAGT ATTAAAAGGTCAAAATGCTGAACAAGATATCAGGCAACTCCGTACCGGAGGAATCCCAAAATTGCCCGCT GCTGTAAAGGAAATCATTAAATCCTCTGAAAATGCTTTTGCTGTGAGGCTTTCTCCTTATGACAACGATA AATTTACTCGCTTTGATGACCCTTTATTCAATGTCAAAAGAAACATCTCTAAATACGATACGCCCTCAAG GCAAGCTCCTATTCCAATATACGAGGGATTAGGGTATCGCCTGCGTTCAACTCTGTTCCCGAAAGAGAAA ACACCGACTCCAATCAATAAAAAATCACTTAGAGAAAAAGTAAAAAGCACTGTTCTTAGTCATTATAAAG AGGAAGATAGAATTGATGGAGAAAAAAGAGATGAAAAATTAAGCGAGTTAATTACTAAACTTCAAAATGA ACTTGTAAAAGAGTTAGTAAAAATTGATCCTCAATATTCGAAGCTATCATTATCTAAAGATCCAAGAGGA AATGAAATAAATTACAATTATTTAGTTAATAGTTTAATGCTTGTAGATGACGACTCTAAAATTGGTGAGT GGATTGAAACGATTCTCGACTCTACAGTAGATTCGACTGTATGGGAAGCTCAAGCATCCAGCCCTTTCTA TGATGGCGCTAAAGAAATAAAATCAGACAAAGAAGCAGACAGGATATCCATCAGAGTTCAGTACCTGTTG GCGGAAGCAAACATTTATTGTAAAACAAACAAATTATCGGACGCTAACTTCGGAGAATTTTTCGACAAAG AGCCTCATGCTACTGAAATTGCGAAAAGAGTAAAGGAAGGATTTACGCAAGGTGCAGAGATAGAACCAAT TATATACGACTACATTAACAACAACCATGCTGAATTGGGATTAAAATCCCCGTTAACAGGCGAACAACTA CAAGAAATCACTGAGAAATTTACGAGACATTATAATACGATTAAGGAATCTCCTCATTTTGATGAGTTTT TTGTCGCAGATCCTGATAAAAAAGGCAATATCTTTTGTCATCAAGGCAGAATCAGTTGTCATTTTCTGGA TTTCTTTACTCGACATACCAAAGGCAATTATCCACTTGGTGATCTTGCAAATCATCAGGAATCTCTCCAA AAAGGAACCTCCAATCGGTTACATCACAAAAATGAGTTAGTAGCTCAGGGATATGAGAGACTGGATCAAT TCAAGAAAGAAGTTGTAAAACTACTGGCTGAGGATAAACCAAAAGAATTATTGGATTACTTGCTCACTAA CTCACCCACAGGTGTTCCAAATTACTCCATGCTTTCAAAGGAAACTCAAAATTACATTGCTTACAATCGT AACTGGCCAGCCATTCAAAAAGAGCTGGAACAGACTACCAACATACCAGAGAATCAAAAACAAGATCTCC TAAGATTGCTTTCTCGTGATAATCTGAGCCACGATAATCTAAGCGCAATTACCTGGTCAAAATATTCCTC CAAGCCATTATTGGATGTGGAATTAAACAAAATCGCTGAAGGATTAGAACTCACTGCAAAAATTTACAAT GAAAAAAGAGGAAGTGAATGGTGGTTTAAAGGTTCAAGAAATCAAGCTCGTAATACTCAATGTGAAGAAT TGCAAAGAGTGGCTAAAGAAATCAATGCTCTTTTGCAAAATGAAACTTTAACCAAAAGCCAGGTCCTTGA AAAAGTTTTAAACTCTATAGAAACATTGGATAAAATTGACAGAGACATTTCCGCCGAATCCAATTGGTTT AAAAGTACTTTGCAAAAGGAAGTCAGATTATTTCGGGATCAATTGAAAGATATTTGCCAATTGGATAAGT ATGCCTTTAAATCAACAAAACTTGATGAAATTATCTCTCTGGAAATGGAAGAACAATTTCAAAAGATAGA AGATCCTGTTGTTCAGAAAATTGTCAGGGACTTGCCTGCTCATTGCCACAATGATGAAGCAATTGAATTC TTTAAGACATTGAACCCTGAAGAGGCAGCTAAAGTGGCTAGCTATTTAAGCCTGGAATACCGGGAAATTA ATAAATCAACAGATAAGAAAACTCTCCTTGAGCAAGATATTCCCAAACTGTTTAAAGAAGTAAATGCACT ACTACTCTCCAAATTAAAAGAAGAAAAAGCCATTGATGAGCAAGTCCATGAAAAACTCAGTCAACTGGCT GACAAAATTCCTCCTGAGCATTTTACAAGAAATAACATTATAAAATGGTCTGCTACCCCTGAAAAGCTTG AGGAATCAAATCTTAATGAGCTAATCAAATCAGTCGAAAGCCCTACTACTAAACAAACATCAAAACAATT CAGGGAAGCCATGGGTGAAATCACTGGAAGAAATGAGCCTCCTAAAGACACCCTTGGGCATACAATATAG |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |