| Effector Protein ID: 148359697 |
 T4SS name [ID] | Dot/Icm [42] |
| Gene symbol | - |
| Locus tag | LPC_1618 |
| Strain | Legionella pneumophila str. Corby |
| Replicon | chromosome [GenBank: NC_009494] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2527727..2532367 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | LaiA/SdeA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | An integrin-like protein involved in adhesion to and invasion of human lung alveolar epithelial cells. (Chang et al. 2005) |
| UniProt ID | A5IDV8 |
| KEGG ID | lpc:LPC_1618 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | SidE [PF12252], Evalue: 0, Aligned region: 1..512 SidE [PF12252], Evalue: 0, Aligned region: 517..1486 |
| Protein Sequence: 1546 a.a. [Download] |
| >gi|148359697|ref|YP_001250904.1| hypothetical protein LPC_1618 [Legionella pneumophila str. Corby] MPKYVEGVELTQEGMHAIFARMGYGDITSGSIYNGVPTIDTVALNRQGFMPVLTGVGPHRDSGHWIMLIK GPGNQYYLFDPLGKTSGEGYQNILAAQLPMGSNLSVIPNDSGLNMGLCGYWVASAGLRAHQALNQPIPPT LLNLGQTITDEMRNELDHDGYRKITGWLRAVADEFPHGDEQLDAKALRENTEKDLKIEIPTLVLPGKDTS PKEAPVKPTAPQDKSVPVWNGFSLYTDVTVQAAVQYAYDNYLGKPYTGPVESAPANFGGQMVYRQHHGLS HTLRTMAYAELIVEEARKAKLRGETLGKFKDGRTIADVTPEELKKIMIAQAFFVAGRDDEESEKNYAKYH QQSRDAFLKYVKDNESTLIPDVFKDQEDVNFYAMVIEDKKKDWDSTPAHVLINQGHMVDLVRVKQPPESY LESYFKSMQRWIGTQATEAVFAIQRQFFHATYEAVTGFDSDNKEPHLVTSGQFRYVIGEDGKPIREAPKM GQKEGDIKFFPPTYKLKGKERFAFGNAGLGRYVIGEDGQPIRNEPAKGEKQGTLAFFPASYQLQGNERFM RVDEYLKLDEVQQRFPGIGKHLEGGIPGMKYMDYMNRLNSLNRAKCETDVGFCLKQLQTAHDKAKIDPVK EAFQSSKEKGRRQPNVDEIAAARIIQQILANPDCIHDDHVLINGQKLEQQFFRDLLAKCEMAVVGSLLND TDIGNIDTLMRHEKDTEFHSTGKEAIPNKIGAKWEEKQNKYNASRNITETKHNLIFLMQDDSWYFSRVNA IAQNRDTGSTFKEVLITTLMTPLTSKALVDTSSAPAPKRLFRGLNFSEEYAQGLINQANTMIANTTERLF TDHSPEAFKQIKLNDLSKMSGRTNASTTTNIELCRTIWDSNVIFEMLDPDDLLQPKQVGRHGAGTESEFS VYLPEDVALVPVKVTLDESKTQNGENRYIFTFVAVKSPDFIPRHESGYAVEPFLRMQTAKLAEIKSSIEK TQVAPDLNRIIDLQSDLDAVKFTDLSPGYKGFIKNTVGPVLENCLKGFMESDAVALSKVLAAFPPDGQWS AFNFEEARQAKRQMDALKQMVANKVVLDALTQCQDALEKQNIAGALDALKNIPSEKEIGTIRRELREQIQ STRQELESLQRAVVTPVVTDEKKVRERYDALIENTSKKITELETGKLPNLDAVKKGISNLSNLKQEVTVL RNEKIRMHVGTDKVDFSDIEKLEQQIQVMDTKLADAYLLEVTKQISALENEKPKNQTELKTKIAAFLDRT ADIEAFRNDRVKKHGSSTDPLDLSDLDKLSGNLQRINQSLVSSLINTIRVSISQMEAKTFHMQEKEIQQN FELLAKLEKTLDKSKTAEKLREEIPKLNDLLVAKQKTYPQMVQLQLKSEVFITQLREVCQANYDDLDKTR NERLRELDRLDKEAGIGRMVGNLLWGITNKVGLTTDERLDIRTKQQSLARFRTELFNDKIDTDQLISNLA RKRPTELQEGLGISPDNAMDLYMVLTNLESKTTSPEKLEERMKAIDDISTKIGREPEHLKFVMVEEDESN KKTIGF |
| - |
| Nucleotide Sequence: 4641 bp [Download] |
| >gi|295815281|ref|NC_009494.2|:2527727-2532367 Legionella pneumophila str. Corby chromosome, complete genome ATGCCTAAGTATGTCGAAGGGGTAGAACTCACTCAAGAAGGTATGCATGCTATTTTTGCACGCATGGGGT ATGGGGATATTACCAGCGGTAGCATTTACAACGGAGTCCCAACTATTGACACAGTTGCCCTGAACAGGCA AGGTTTCATGCCCGTGTTAACCGGAGTAGGACCACACAGAGACTCCGGCCACTGGATTATGTTAATCAAG GGACCTGGTAACCAATACTACCTCTTTGACCCATTAGGCAAAACCTCGGGTGAAGGCTATCAAAACATTT TAGCAGCACAATTACCAATGGGCTCTAACCTTTCAGTTATTCCTAATGATTCCGGTTTGAATATGGGATT ATGCGGCTATTGGGTCGCCTCTGCCGGTTTAAGAGCACACCAGGCATTAAATCAACCCATCCCTCCTACT TTGTTGAATCTGGGTCAAACCATTACCGATGAAATGCGTAATGAGCTCGATCATGACGGTTATCGAAAAA TTACCGGCTGGTTACGAGCCGTTGCTGATGAATTTCCTCACGGTGATGAGCAATTAGATGCAAAAGCATT AAGGGAAAACACTGAAAAAGATTTAAAAATAGAAATTCCCACCCTGGTTCTTCCAGGAAAAGACACCTCT CCTAAAGAAGCTCCTGTCAAACCCACTGCACCGCAAGATAAATCTGTGCCTGTCTGGAATGGGTTTTCAT TATATACCGATGTAACCGTTCAAGCTGCAGTACAATACGCTTATGACAATTATCTGGGCAAACCTTATAC CGGACCAGTTGAATCAGCACCCGCTAATTTTGGTGGGCAAATGGTGTATAGACAGCACCATGGGCTTTCC CATACTTTACGGACCATGGCTTATGCGGAATTGATTGTTGAAGAAGCACGTAAAGCCAAATTGCGAGGTG AAACATTAGGAAAATTCAAAGACGGCCGTACTATTGCTGATGTTACCCCTGAAGAACTGAAAAAAATCAT GATTGCCCAGGCGTTTTTTGTAGCTGGAAGAGACGATGAGGAATCCGAAAAAAATTATGCCAAATACCAT CAGCAAAGCCGTGATGCCTTCTTAAAGTATGTGAAAGACAATGAATCCACACTGATTCCTGATGTTTTCA AAGATCAGGAAGATGTCAATTTTTATGCCATGGTAATTGAAGATAAAAAGAAAGATTGGGATTCAACTCC AGCGCATGTATTGATTAATCAGGGCCATATGGTCGATTTGGTACGGGTCAAACAACCACCTGAATCCTAT CTGGAAAGTTATTTCAAATCCATGCAACGCTGGATAGGCACCCAGGCAACGGAAGCTGTTTTTGCGATAC AAAGACAATTTTTCCATGCCACTTATGAAGCAGTAACAGGTTTTGACTCTGATAACAAAGAACCTCATCT GGTGACATCTGGTCAATTCCGTTATGTCATCGGTGAAGACGGCAAGCCCATTAGAGAAGCCCCCAAAATG GGGCAAAAAGAAGGTGATATAAAATTTTTTCCCCCCACTTACAAACTGAAAGGAAAAGAACGCTTTGCAT TCGGGAATGCAGGTCTTGGGCGTTATGTCATCGGTGAAGATGGCCAACCTATCCGAAATGAACCTGCAAA AGGTGAGAAACAAGGTACCTTAGCCTTTTTCCCTGCTAGTTATCAGTTACAAGGAAACGAACGCTTTATG CGTGTCGATGAATATCTCAAACTGGATGAAGTACAACAGCGATTCCCCGGGATTGGCAAACATCTGGAAG GTGGGATACCGGGTATGAAGTATATGGATTATATGAATCGACTGAACTCTTTAAACAGGGCAAAGTGTGA AACCGATGTCGGTTTTTGTTTGAAACAATTACAAACAGCCCATGACAAGGCGAAAATTGATCCTGTTAAA GAGGCTTTTCAATCCAGCAAAGAGAAAGGAAGAAGACAACCCAATGTGGATGAAATTGCCGCTGCCCGCA TCATTCAGCAAATCTTGGCCAATCCGGATTGCATCCATGATGATCATGTGCTCATCAATGGCCAGAAACT GGAACAACAATTCTTCCGTGACTTGTTAGCGAAATGCGAGATGGCTGTCGTAGGCTCACTGCTCAATGAC ACCGACATAGGAAACATTGATACTTTAATGCGACATGAAAAAGACACCGAGTTTCATTCTACTGGAAAAG AAGCAATTCCAAACAAAATTGGAGCTAAATGGGAAGAGAAACAAAATAAATATAATGCTAGTCGCAACAT CACCGAAACGAAACACAATTTAATTTTCCTCATGCAAGATGATTCCTGGTACTTTAGCCGAGTCAATGCC ATCGCACAAAACAGAGATACAGGTTCCACTTTCAAGGAAGTGCTGATTACTACTTTAATGACGCCTTTGA CCAGTAAAGCATTAGTCGATACCTCAAGTGCCCCTGCTCCGAAAAGACTGTTTCGTGGATTAAATTTTTC AGAAGAATATGCTCAGGGATTAATCAATCAAGCCAATACAATGATCGCCAATACGACAGAGCGTCTATTT ACAGATCATTCACCAGAAGCCTTTAAACAAATCAAGTTAAATGATTTAAGTAAAATGTCCGGCAGAACTA ATGCCAGTACAACCACGAATATCGAACTGTGTAGAACAATCTGGGATTCTAATGTCATCTTTGAAATGCT TGACCCGGATGATTTGCTGCAGCCCAAGCAAGTAGGACGCCATGGGGCAGGCACTGAAAGTGAATTCTCC GTTTATTTGCCAGAGGATGTTGCCCTGGTCCCAGTCAAAGTGACCCTTGATGAAAGTAAAACGCAAAATG GAGAAAATCGGTATATCTTTACCTTTGTTGCCGTAAAAAGCCCTGACTTTATACCACGGCATGAAAGCGG CTATGCGGTTGAACCGTTTTTAAGAATGCAAACTGCCAAGTTAGCCGAAATCAAAAGCTCTATTGAAAAA ACCCAGGTAGCGCCTGACCTAAATAGAATAATCGATTTACAAAGCGACTTAGACGCAGTGAAATTTACAG ATTTATCCCCTGGATATAAAGGATTTATTAAAAATACAGTTGGCCCTGTTTTGGAAAATTGCCTTAAGGG ATTCATGGAGAGTGATGCGGTCGCTTTAAGTAAGGTCTTAGCAGCATTTCCACCCGACGGACAATGGTCA GCCTTCAATTTTGAAGAAGCAAGGCAAGCCAAAAGACAGATGGATGCCCTCAAACAAATGGTTGCAAATA AAGTAGTGCTTGACGCCTTGACTCAATGCCAGGACGCGCTGGAAAAGCAAAATATCGCTGGCGCACTGGA TGCTCTCAAAAACATACCATCTGAAAAAGAGATAGGTACCATTAGAAGAGAGCTAAGAGAACAAATCCAG AGCACCAGGCAAGAACTGGAATCATTGCAACGTGCGGTTGTTACTCCTGTAGTAACAGATGAAAAGAAAG TAAGAGAACGCTATGATGCCCTGATAGAAAACACATCGAAGAAAATTACTGAACTTGAAACAGGAAAGTT ACCCAATCTCGATGCGGTCAAGAAAGGCATATCTAACTTGAGCAATCTGAAACAAGAGGTAACCGTATTG CGTAATGAAAAAATACGGATGCACGTTGGAACTGATAAAGTTGATTTTTCAGATATTGAAAAACTGGAAC AACAAATACAGGTCATGGATACCAAATTAGCCGATGCTTATTTACTTGAAGTAACCAAACAAATTTCAGC GCTTGAAAATGAAAAACCCAAAAATCAGACTGAATTGAAAACAAAAATAGCAGCATTTCTTGACAGAACC GCTGATATTGAGGCGTTCCGTAATGATCGAGTCAAGAAACACGGATCATCAACAGATCCGCTGGACCTCT CTGATTTGGATAAATTAAGTGGCAACTTACAGCGCATCAATCAATCCCTTGTTTCGTCTTTGATAAATAC TATCCGGGTTTCCATCAGTCAAATGGAAGCGAAAACTTTTCACATGCAAGAAAAGGAAATACAACAGAAT TTCGAGTTACTCGCAAAACTCGAAAAAACATTGGATAAGTCAAAGACTGCAGAAAAACTAAGGGAGGAAA TTCCCAAGCTAAACGATTTACTGGTTGCCAAACAAAAAACCTATCCTCAAATGGTGCAACTGCAACTCAA GAGTGAAGTCTTCATCACTCAATTACGTGAGGTATGTCAAGCTAACTATGACGATCTGGATAAAACAAGA AATGAAAGATTACGAGAACTGGATCGGCTGGACAAAGAAGCTGGAATAGGGAGAATGGTGGGCAATCTGC TCTGGGGCATTACCAACAAAGTAGGTTTAACTACAGATGAACGACTTGACATCAGGACTAAACAGCAATC GCTTGCACGATTCAGGACTGAATTATTCAATGACAAGATTGATACGGATCAGCTAATCTCTAATTTGGCA AGGAAAAGGCCAACCGAACTGCAAGAAGGATTGGGAATATCTCCTGACAATGCGATGGATTTATATATGG TCTTAACCAATTTGGAGTCTAAAACCACTTCCCCAGAAAAACTTGAAGAAAGAATGAAAGCAATCGATGA CATTTCAACCAAGATAGGCAGAGAGCCTGAGCATTTGAAATTTGTCATGGTTGAAGAAGATGAATCCAAT AAAAAAACTATAGGATTTTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |