| Effector Protein ID: 148358680 |
 T4SS name [ID] | Dot/Icm [42] |
| Gene symbol | - |
| Locus tag | LPC_0557 |
| Strain | Legionella pneumophila str. Corby |
| Replicon | chromosome [GenBank: NC_009494] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 3096580..3097737 [-] |
| Product | acid sphingomyelinase-like phosphodiesterase |
| Effector type | Protein |
| Descripton | LegS1 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | A5IAZ1 |
| KEGG ID | lpc:LPC_0557 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Metallophos_2 [PF12850], Evalue: 5.8e-08, Aligned region: 23..265 Metallophos [PF00149], Evalue: 7.9e-05, Aligned region: 23..228 |
| Protein Sequence: 385 a.a. [Download] |
| >gi|148358680|ref|YP_001249887.1| acid sphingomyelinase-like phosphodiesterase [Legionella pneumophila str. Corby] MNFSIRVILLLTCFVSLAFSAPKFLTISDIHYGAENIAKDGQDTGKEFLDVTFKRFEELSQNVDFILHLG DLPTHSLFSTSKKEEYEQVVFHGLHEANPGQKPMFYITGNNDSLLGNYQPFSSDNKSPLNLALDWDGACV HCDGLIIDDTHMRKDGYYSSYVIPNNKEIILIALNSVQWTKTPVFLPKYPNQQRDAFVQLFWLEQQLKNH RAKQLLLAMHVPPGTAYNGNRFWHEIYLDRFLTLLDKYHRSYDQITILFSHSHMEEFRKIKLSDGSTIYA FSTPGISRAHHNNPGMKIFDLDKQMRVRNFTTYFTSDLYEWGNEHYQAMNIPEAIFPNCQNKTIPQCLDT LSPEQVCNNLEAGLFYGVKSTRVPYQGCIKTYQIN |
| - |
| Nucleotide Sequence: 1158 bp [Download] |
| >gi|295815281|ref|NC_009494.2|:c3097737-3096580 Legionella pneumophila str. Corby chromosome, complete genome TTGAATTTTAGTATTCGGGTAATTCTTTTATTAACATGTTTTGTTTCTTTAGCCTTTTCTGCACCAAAAT TTCTAACAATCTCTGATATTCATTATGGTGCAGAAAATATAGCAAAGGATGGGCAGGATACTGGAAAGGA GTTTTTGGATGTCACGTTCAAACGATTTGAGGAATTGTCTCAAAATGTAGATTTTATTTTACATTTGGGT GATCTGCCTACTCACTCGTTATTTTCGACATCTAAAAAAGAAGAATACGAACAAGTTGTATTTCATGGTT TGCATGAAGCGAATCCGGGTCAAAAGCCCATGTTTTATATTACAGGAAATAATGATTCCTTGCTTGGCAA TTACCAGCCATTTTCTTCAGACAATAAGTCGCCACTCAATTTGGCTCTGGATTGGGATGGTGCTTGCGTT CATTGTGATGGGTTAATTATTGATGATACTCATATGCGCAAGGATGGATATTACTCCAGTTATGTCATCC CCAATAATAAAGAGATTATTTTAATAGCACTTAATTCGGTTCAATGGACCAAGACCCCTGTTTTTTTACC AAAGTACCCTAATCAACAAAGGGATGCCTTTGTACAATTATTTTGGCTTGAACAACAATTAAAAAATCAT CGTGCAAAGCAATTGTTGTTGGCGATGCATGTTCCTCCTGGTACAGCCTATAACGGCAACCGGTTTTGGC ATGAAATTTATCTGGATAGATTTTTGACGTTATTAGACAAATATCATCGATCCTATGATCAAATCACCAT ACTGTTCTCACACTCCCATATGGAGGAATTCAGGAAAATCAAATTATCCGATGGCTCAACTATTTATGCG TTTTCTACTCCCGGAATTAGCAGGGCGCATCACAACAATCCCGGGATGAAAATTTTTGATTTAGACAAGC AAATGAGGGTCAGAAATTTTACTACTTATTTTACGTCCGATTTGTATGAGTGGGGTAATGAGCATTATCA AGCCATGAACATTCCTGAAGCCATTTTTCCAAATTGTCAAAATAAAACGATACCCCAGTGCCTGGACACC TTAAGTCCAGAGCAAGTATGCAATAATCTGGAAGCAGGACTATTTTATGGGGTTAAAAGTACGCGTGTTC CCTATCAAGGATGCATTAAAACTTACCAGATCAATTAA |
| Reference |
(1) Gomez-Valero L et al. (2014). Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires' disease. Genome Biol. 15(11):505. [PudMed:25370836] 
|
(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
|
| experimental literature |
| in silico analysis literature |