| Effector Protein ID: 148358487 |
 T4SS name [ID] | Dot/Icm [42] |
| Gene symbol | - |
| Locus tag | LPC_0353 |
| Strain | Legionella pneumophila str. Corby |
| Replicon | chromosome [GenBank: NC_009494] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 380892..382445 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | LegG2 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | LegG2, which has a Ras GEF domain, is believed to be involved in GDP-to-GTP exchange in Ras GTP-binding protein (de Felipe, et al. 2005) |
| UniProt ID | A5IAE8 |
| KEGG ID | lpc:LPC_0353 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | RasGEF [PF00617], Evalue: 2.3e-09, Aligned region: 95..256 |
| Protein Sequence: 517 a.a. [Download] |
| >gi|148358487|ref|YP_001249694.1| hypothetical protein LPC_0353 [Legionella pneumophila str. Corby] MIGMRAEQCNLKSFFVHSLKNKSNLLPLIACFNNREINMPKILDSNAYREMENELNNLFEQIYKHGKNDR TAITLQVQQFLDNLSESIRDHSRLLLTNIAREELIYFKEKKPGDSREKFQNIDKMSDYFNNLSALINFSV MQQEDPTLRVFYYDMYIQLMNFCYLKGDLFGAGAIYTGLIANNLPNSIDRKQLSSESRLIFKDCEEKFKR LFNLSTTYNEHTNLKRQFKTALIPALPSLLTVQIYTKDAYDNSVSDFERVQEKLRQLDIEHNRFLNQLQN DHSTWSKAYYDYMSNVYLPQSIFEYTTLLREYEELITTHGGPIAKQFHEDKNSEHLVSFVESTLLENQSD LKLSPFQNERIVEMLSEIDVVKSECSSPDVFDDISWKLREMNCTLVKAKSIGDYTSKIFANLDTPYMEEN TDEDPKPVLVEELQTDDVYQLHHSGMKLIRELEQAIEDHKPKVIYHCSGEANYGFFKEARRRGRHLSPEP MDIEVMDVDVMDYDENDLRNQTVMITV |
| - |
| Nucleotide Sequence: 1554 bp [Download] |
| >gi|295815281|ref|NC_009494.2|:380892-382445 Legionella pneumophila str. Corby chromosome, complete genome GTGATTGGAATGCGTGCTGAACAATGCAACTTAAAATCATTTTTTGTCCACAGTTTGAAAAATAAAAGTA ATTTATTGCCATTAATTGCATGTTTTAATAATAGAGAAATCAATATGCCTAAAATTTTAGATAGCAATGC ATATCGCGAGATGGAAAATGAGCTCAATAATCTTTTCGAGCAAATTTATAAGCATGGTAAAAATGACAGA ACCGCGATTACATTACAAGTTCAGCAATTTTTAGATAATTTGAGCGAATCCATTAGGGATCATTCCCGCT TATTGCTTACCAATATTGCCAGAGAAGAACTCATTTATTTTAAGGAAAAGAAACCTGGAGATTCGCGAGA GAAATTTCAAAATATCGATAAGATGAGTGATTACTTTAACAATTTATCTGCATTGATTAATTTCTCTGTA ATGCAACAAGAAGATCCTACTCTGCGGGTTTTTTATTATGATATGTATATTCAACTAATGAATTTTTGCT ATCTTAAAGGGGATTTGTTTGGAGCGGGTGCAATTTATACGGGTTTAATAGCTAATAACCTCCCTAACTC TATTGATCGGAAGCAATTGAGCTCCGAGAGTCGCCTGATTTTTAAAGATTGTGAAGAAAAATTTAAGCGA TTATTCAATCTCTCAACTACATACAATGAACACACTAATTTAAAAAGACAATTCAAAACTGCTTTGATAC CCGCATTACCGTCACTTCTCACGGTTCAGATATATACTAAAGACGCTTACGATAACTCTGTCAGCGATTT TGAAAGAGTTCAGGAGAAGTTACGTCAGTTGGATATAGAACATAATCGGTTTCTTAATCAATTACAAAAT GACCATTCAACCTGGTCTAAAGCTTATTATGATTATATGAGTAATGTTTATCTCCCGCAAAGTATATTCG AATACACGACTCTTTTAAGAGAGTATGAAGAACTTATCACAACGCATGGTGGCCCTATTGCGAAACAGTT TCATGAGGATAAGAATTCAGAACATCTGGTAAGCTTTGTTGAATCGACGCTATTAGAAAATCAATCAGAT CTCAAATTATCTCCTTTTCAAAATGAGAGAATTGTTGAAATGCTTTCCGAGATTGACGTGGTAAAAAGTG AGTGCTCAAGCCCAGATGTGTTTGATGACATCTCCTGGAAGTTGAGAGAAATGAATTGTACTTTGGTAAA AGCCAAATCTATTGGTGATTATACTTCCAAAATTTTTGCAAATCTTGATACTCCATACATGGAAGAAAAT ACGGATGAAGATCCGAAACCAGTGCTTGTAGAAGAACTGCAAACGGATGATGTGTACCAACTTCACCATA GTGGTATGAAATTGATACGTGAGCTCGAACAGGCTATAGAAGATCATAAACCGAAGGTTATTTATCATTG TTCAGGTGAGGCAAACTATGGTTTCTTTAAGGAAGCCAGAAGGAGGGGGAGGCATTTGAGTCCAGAACCA ATGGATATCGAAGTCATGGATGTGGATGTGATGGATTATGATGAGAACGATTTACGTAATCAAACCGTTA TGATTACGGTGTAG |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |