| Effector Protein ID: 148358485 |
 T4SS name [ID] | Dot/Icm [42] |
| Gene symbol | - |
| Locus tag | LPC_0351 |
| Strain | Legionella pneumophila str. Corby |
| Replicon | chromosome [GenBank: NC_009494] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 377462..378172 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | SdbA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | SdbA has been proved to contribute to sustained NF-kappaB activation in A549 epithelial cells, and are essential for L. pneumophila replication (Bartfeld, et al, 2009) |
| UniProt ID | A5IAE6 |
| KEGG ID | lpc:LPC_0351 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 236 a.a. [Download] |
| >gi|148358485|ref|YP_001249692.1| hypothetical protein LPC_0351 [Legionella pneumophila str. Corby] MHKKYNYYSLEKEKKTFWQHILDILKAPFRLPGWVVSFFLARNITHVALNPNNIPQQRLIHLTKTSNRPE DDIVVINFKKRPPHKWFNDTLIKIANTIAALPFVTPRLRTRLHYDNENDINHVNKLLAEIDALVQGKSKQ KYCKGRAFDWSKIHLKGLEFLDPKMRGYVYEQLHEKYGYVSYTTKREPNIEFFTLKTPDGSELDSVQVTG EDEEKKPMRERKFIITCIARDQNFIN |
| - |
| Nucleotide Sequence: 711 bp [Download] |
| >gi|295815281|ref|NC_009494.2|:377462-378172 Legionella pneumophila str. Corby chromosome, complete genome ATGCATAAAAAATACAACTACTACAGTCTTGAAAAAGAAAAAAAAACATTCTGGCAACATATACTGGATA TTCTGAAGGCCCCATTTAGGCTACCTGGTTGGGTCGTTTCTTTTTTCTTGGCACGAAATATTACTCATGT GGCATTAAATCCTAATAATATTCCGCAACAACGTTTAATACATCTTACTAAAACAAGCAATCGTCCAGAG GATGATATTGTTGTCATTAATTTCAAAAAACGGCCGCCTCACAAATGGTTTAATGACACGCTGATTAAAA TAGCCAATACGATTGCGGCTCTTCCTTTTGTAACACCAAGATTACGTACAAGATTACATTACGATAATGA GAATGACATCAATCATGTGAACAAGTTGCTTGCCGAGATCGATGCGCTTGTTCAGGGCAAATCAAAACAA AAGTATTGCAAAGGCAGGGCATTCGATTGGTCAAAAATTCATCTGAAGGGATTGGAGTTCCTGGACCCTA AAATGAGAGGGTATGTTTATGAACAACTGCATGAAAAATATGGTTATGTCTCATATACAACAAAACGCGA ACCTAATATTGAATTTTTCACCTTAAAAACTCCTGATGGATCTGAATTGGATTCAGTGCAAGTTACAGGT GAAGATGAAGAAAAAAAACCAATGAGGGAGCGCAAGTTTATTATTACCTGTATTGCGCGGGATCAAAATT TCATTAATTGA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |