Detailed information NTG0948146

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXR41_RS09895
• Genome accession: NZ_CP147694
• Coordinates: 1994433..1995476 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN102-2
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1989433..2000476

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR41_RS09865 (UXR41_09865)	-	1989851..1991107 (-)	1257	WP_001795438.1	aminopeptidase	-
UXR41_RS09870 (UXR41_09870)	-	1991110..1991310 (-)	201	WP_000180461.1	DUF1128 family protein	-
UXR41_RS09875 (UXR41_09875)	-	1991457..1991921 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXR41_RS09880 (UXR41_09880)	-	1991928..1992203 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXR41_RS09885 (UXR41_09885)	-	1992481..1993698 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXR41_RS09890 (UXR41_09890)	vraR	1993814..1994443 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXR41_RS09895 (UXR41_09895)	vraS	1994433..1995476 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXR41_RS09900 (UXR41_09900)	liaF	1995473..1996174 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXR41_RS09905 (UXR41_09905)	-	1996189..1996575 (-)	387	WP_001110179.1	hypothetical protein	-
UXR41_RS09910 (UXR41_09910)	map	1996792..1997550 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXR41_RS09915 (UXR41_09915)	-	1998078..1999064 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXR41_RS09920 (UXR41_09920)	-	1999495..1999908 (-)	414	WP_001549145.1	hypothetical protein	-
UXR41_RS09925 (UXR41_09925)	-	1999937..2000047 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=948146 UXR41_RS09895 WP_001017131.1 1994433..1995476(-) (vraS) [Staphylococcus aureus strain BSN102-2]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=948146 UXR41_RS09895 WP_001017131.1 1994433..1995476(-) (vraS) [Staphylococcus aureus strain BSN102-2]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1