Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   VXJ98_RS06980 Genome accession   NZ_CP142855
Coordinates   1399933..1400562 (-) Length   209 a.a.
NCBI ID   WP_002450048.1    Uniprot ID   A0A1L8Y4G9
Organism   Staphylococcus hominis strain Sh8213     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1394933..1405562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VXJ98_RS06950 (VXJ98_06950) - 1395636..1396169 (-) 534 WP_017175224.1 acyl-CoA thioesterase -
  VXJ98_RS06955 (VXJ98_06955) - 1396202..1397449 (-) 1248 WP_017175225.1 aminopeptidase -
  VXJ98_RS06960 (VXJ98_06960) - 1397461..1397667 (-) 207 WP_002450082.1 DUF1128 domain-containing protein -
  VXJ98_RS06965 (VXJ98_06965) - 1397809..1398273 (+) 465 WP_017175226.1 low molecular weight protein-tyrosine-phosphatase -
  VXJ98_RS06970 (VXJ98_06970) - 1398279..1398560 (+) 282 WP_002450075.1 hypothetical protein -
  VXJ98_RS06975 (VXJ98_06975) - 1398652..1399854 (+) 1203 WP_017175227.1 YihY/virulence factor BrkB family protein -
  VXJ98_RS06980 (VXJ98_06980) vraR 1399933..1400562 (-) 630 WP_002450048.1 two-component system response regulator VraR Regulator
  VXJ98_RS06985 (VXJ98_06985) vraS 1400564..1401598 (-) 1035 WP_017175228.1 sensor histidine kinase Regulator
  VXJ98_RS06990 (VXJ98_06990) liaF 1401595..1402296 (-) 702 WP_017175229.1 cell wall-active antibiotics response protein LiaF -
  VXJ98_RS06995 (VXJ98_06995) - 1402318..1402704 (-) 387 WP_017175230.1 hypothetical protein -
  VXJ98_RS07000 (VXJ98_07000) - 1402896..1403033 (+) 138 WP_176743805.1 hypothetical protein -
  VXJ98_RS07010 (VXJ98_07010) map 1403381..1404133 (-) 753 WP_017175231.1 type I methionyl aminopeptidase -
  VXJ98_RS07015 (VXJ98_07015) - 1404307..1405296 (+) 990 WP_017175232.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23592.26 Da        Isoelectric Point: 5.3673

>NTDB_id=927423 VXJ98_RS06980 WP_002450048.1 1399933..1400562(-) (vraR) [Staphylococcus hominis strain Sh8213]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGSSGKEAIEKAHTLNPDLILMDLLMNDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYRGESVFEPEVLVKMRNRMKKKAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=927423 VXJ98_RS06980 WP_002450048.1 1399933..1400562(-) (vraR) [Staphylococcus hominis strain Sh8213]
ATGACGATTAAAGTATTATTTGTAGACGATCATGAAATGGTTAGAATTGGTATTTCAAGTTATTTATCTACTCAATCTGA
TATTGAAGTAGTAGGAGAAGGATCATCAGGAAAAGAGGCAATTGAAAAAGCACATACGTTAAATCCTGATTTAATTTTAA
TGGATTTGTTAATGAATGATATGGACGGTGTAGAAGCGACGACACAAATAAAAAAAGATTTGCCTCATATCAAAGTAGTC
ATGTTAACAAGTTTTATAGAAGATAAAGAAGTATATAGAGCACTTGATGCAGGGGTGGATAGTTATATATTAAAAACGAC
AAGTGCCAGTGATATTGCAGAAGCAGTTAGAAAAACATATCGTGGAGAATCTGTATTCGAGCCAGAAGTTTTAGTAAAAA
TGAGAAATAGAATGAAGAAGAAAGCAGAATTATATGAAATGCTCACTGAACGTGAAATGGAAATATTGTTATTAATTGCT
AAAGGCTATTCTAATCAAGAAATTGCCAGTGCTTCACATATTACAATTAAAACAGTAAAAACACATGTGAGTAATATTTT
AAGTAAACTAGAGGTACAAGATAGAACACAAGCGGTTATTTATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L8Y4G9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378