Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VNN26_RS01905 Genome accession   NZ_CP141690
Coordinates   374248..374931 (-) Length   227 a.a.
NCBI ID   WP_019292408.1    Uniprot ID   A0A139MDU9
Organism   Lactococcus petauri strain R22-11 BR-C     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 369248..379931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN26_RS01885 (VNN26_01885) - 369601..370812 (-) 1212 WP_206888277.1 cysteine desulfurase -
  VNN26_RS01890 (VNN26_01890) sufD 370812..372068 (-) 1257 WP_019293599.1 Fe-S cluster assembly protein SufD -
  VNN26_RS01895 (VNN26_01895) sufC 372140..372910 (-) 771 WP_017368843.1 Fe-S cluster assembly ATPase SufC -
  VNN26_RS01900 (VNN26_01900) - 372988..374244 (-) 1257 WP_019293600.1 MraY family glycosyltransferase -
  VNN26_RS01905 (VNN26_01905) mecA 374248..374931 (-) 684 WP_019292408.1 adaptor protein MecA Regulator
  VNN26_RS01910 (VNN26_01910) - 375178..376086 (+) 909 WP_206888275.1 diacylglycerol kinase family protein -
  VNN26_RS01915 (VNN26_01915) rpoC 376179..379826 (-) 3648 WP_206888273.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26254.39 Da        Isoelectric Point: 4.0031

>NTDB_id=918207 VNN26_RS01905 WP_019292408.1 374248..374931(-) (mecA) [Lactococcus petauri strain R22-11 BR-C]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYEDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETINSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=918207 VNN26_RS01905 WP_019292408.1 374248..374931(-) (mecA) [Lactococcus petauri strain R22-11 BR-C]
ATGCAATACGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACAAATCAGTCAATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAACTAGGACTTGAGGAAAGGT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATTATTGTTACTGAAGAAAATATTGAT
ATTGATCCCAATAATCTCCCAGATGATCCCGAAGAATTTGAGCAACTTATGACGGATTTCTTTGGACGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACAAAAGAAACAAAAGTAGAAAATAAACCAGATCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAACATGTCTCAACTTTTAACAGCAGTAAAAAATGTTAAAATTGATGCAGAG
GAATCTGAACTTTATAGCTATGAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAGTCAAAAGGAAAGACAGCCGT
AAGTTCGATGCGTGCCCGAATGTTAGAATACGGACAGGAAACGATCAACAGTCGCGAAACACTACAAGAATACGGCGAGA
TACTAATCAATACACGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139MDU9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.077

100

0.555
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555