Detailed information NTG0091244

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: L6411_RS04415
• Genome accession: NZ_AP025333
• Coordinates: 916352..917089 (+)
• Length: 245 a.a.
• NCBI ID: WP_156020933.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-189
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 911352..922089

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L6411_RS04400 (GUT189_08290)	-	911571..912839 (+)	1269	WP_237374449.1	dihydroorotase	-
L6411_RS04405 (GUT189_08300)	nt5e	912972..915041 (+)	2070	WP_155965493.1	cell surface ecto-5'-nucleotidase Nt5e	-
L6411_RS04410 (GUT189_08310)	-	915423..915806 (-)	384	WP_227985750.1	hypothetical protein	-
L6411_RS10010	-	916160..916321 (+)	162	WP_155973172.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
L6411_RS04415 (GUT189_08320)	comE/blpR	916352..917089 (+)	738	WP_156020933.1	response regulator transcription factor	Regulator
L6411_RS04420 (GUT189_08330)	-	917103..918443 (+)	1341	WP_237374450.1	sensor histidine kinase	-
L6411_RS04425 (GUT189_08340)	-	918500..918625 (-)	126	WP_079276156.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
L6411_RS04430 (GUT189_08350)	-	918882..919136 (+)	255	WP_237374451.1	Blp family class II bacteriocin	-
L6411_RS04435 (GUT189_08360)	-	919152..919358 (+)	207	WP_237374452.1	Blp family class II bacteriocin	-
L6411_RS04440 (GUT189_08370)	-	919361..919573 (+)	213	WP_155965503.1	bacteriocin	-
L6411_RS04445 (GUT189_08380)	-	919907..920137 (+)	231	WP_155964186.1	bacteriocin class II family protein	-
L6411_RS04450 (GUT189_08390)	-	920359..920592 (+)	234	WP_155964185.1	bacteriocin	-
L6411_RS04455 (GUT189_08400)	-	920592..920903 (+)	312	WP_162496986.1	bacteriocin immunity protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28520.02 Da
• Isoelectric Point: 7.1059

>NTDB_id=91244 L6411_RS04415 WP_156020933.1 916352..917089(+) (comE/blpR) [Streptococcus ruminantium strain GUT-189]
MNIFVLEDDIVQQTRIEKVLNNLLEKHKIEPKKLIISGKPEQLIASVEEKGAHQLFFLDIEIRSEELKGLKVAKQIRDID
PYAIIIFVTTHSEFMPLSFRYQVSALDYIEKELATKEFESRIETALLYAVSKDSKTVAEDSFYFKSKYAQVQYPFDEVYY
VETSPRPHRVILYTRTDCMEFTASLSDILKQEKRLLQCHRSFLINPANVIKIDRQAKVVYFPNGTHCLVARKKLDVTLAT
IDQLH

Nucleotide

• Length: 738 bp

>NTDB_id=91244 L6411_RS04415 WP_156020933.1 916352..917089(+) (comE/blpR) [Streptococcus ruminantium strain GUT-189]
ATGAATATATTTGTACTAGAAGATGATATTGTACAACAAACAAGGATTGAAAAAGTGCTTAACAATCTTTTGGAGAAACA
TAAAATAGAGCCCAAAAAACTTATTATTTCTGGGAAACCCGAACAGTTGATTGCTTCAGTGGAGGAGAAAGGGGCGCACC
AGTTGTTCTTTTTGGATATTGAGATAAGATCAGAAGAACTTAAAGGTCTTAAAGTCGCTAAACAAATCAGAGATATTGAT
CCTTATGCTATTATTATTTTTGTGACGACGCATTCTGAATTTATGCCTCTCTCTTTTCGTTATCAAGTATCAGCATTAGA
TTATATTGAAAAGGAACTAGCAACGAAAGAATTTGAATCTCGCATAGAGACAGCTTTACTGTATGCAGTGAGTAAAGATA
GTAAAACAGTAGCTGAGGATTCTTTCTATTTCAAATCTAAATATGCCCAAGTTCAGTACCCATTTGATGAAGTTTATTAT
GTTGAAACGTCTCCAAGACCACATAGGGTTATCCTTTATACAAGAACTGATTGTATGGAGTTCACCGCCAGTTTATCAGA
TATTTTAAAGCAAGAAAAGAGACTGTTACAGTGTCATCGTTCGTTTCTTATCAATCCTGCGAATGTTATCAAAATAGATA
GACAAGCCAAAGTTGTTTATTTTCCCAATGGGACACATTGTTTGGTTGCAAGAAAAAAATTAGATGTTACTTTGGCGACT
ATAGACCAGTTGCACTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-234)

• Response regulator receiver domain (Response_reg) (3-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	52.066	98.776	0.514
comE/comE1	Streptococcus equinus JB1	41.841	97.551	0.408