Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   SUT_RS03175 Genome accession   NZ_AP025331
Coordinates   630114..631463 (+) Length   449 a.a.
NCBI ID   WP_024532081.1    Uniprot ID   A0A2Z5TLH3
Organism   Streptococcus ruminantium strain GUT-183     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 625114..636463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUT_RS03150 (GUT183_05820) - 626230..626889 (-) 660 WP_120171455.1 amino acid ABC transporter permease -
  SUT_RS03155 (GUT183_05830) - 626902..627600 (-) 699 WP_120171456.1 amino acid ABC transporter permease -
  SUT_RS03160 (GUT183_05840) - 627615..628451 (-) 837 WP_120171457.1 transporter substrate-binding domain-containing protein -
  SUT_RS03165 (GUT183_05850) - 628461..629222 (-) 762 WP_155964462.1 amino acid ABC transporter ATP-binding protein -
  SUT_RS03170 (GUT183_05860) micA 629417..630121 (+) 705 WP_120171458.1 response regulator YycF Regulator
  SUT_RS03175 (GUT183_05870) micB 630114..631463 (+) 1350 WP_024532081.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SUT_RS03180 (GUT183_05880) vicX 631470..632273 (+) 804 WP_024532080.1 MBL fold metallo-hydrolase Regulator
  SUT_RS03185 (GUT183_05890) pbp2b 632496..634571 (+) 2076 WP_024532079.1 penicillin-binding protein PBP2B -
  SUT_RS03190 (GUT183_05900) recR 634580..635176 (+) 597 WP_024532078.1 recombination mediator RecR -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51069.15 Da        Isoelectric Point: 4.6687

>NTDB_id=91130 SUT_RS03175 WP_024532081.1 630114..631463(+) (micB) [Streptococcus ruminantium strain GUT-183]
MFNQLRYLITTAEFWFVGILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIDGNYADILDLRGSPEITDMANSLNDLSE
VIRLTHDHLEQEKTRLTSILSYMSDGVVATDRIGRVIMINDMAQKQLGLSGKKQEQYHLLEVLDLPDRYTLRDLFAQTPE
IIIEHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMIRMITDLLSLSRIDNQVGQVDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGRITFSMKTTDSQLIVSISDEGLGIPKTDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHRGFIWAKSEYGHGSTFTIVLPYSKDIALDDWDEASEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=91130 SUT_RS03175 WP_024532081.1 630114..631463(+) (micB) [Streptococcus ruminantium strain GUT-183]
ATGTTTAATCAATTACGGTATCTAATTACTACAGCAGAGTTTTGGTTTGTCGGAATTTTGATTGGTTTTCTGATTGCTTT
GACGGTTCTCTTGATTGAAAACTACCGAGATAATAAGCAAATCAAACAACTGAATCAAAAAGTTAATGCTCTCATTGATG
GAAATTATGCAGATATTTTAGATTTGAGAGGGAGTCCAGAAATTACTGATATGGCTAACTCTCTTAATGATTTGTCAGAA
GTTATTCGGCTGACTCATGATCATTTAGAGCAGGAAAAAACACGCTTGACTTCCATTCTTTCCTATATGAGTGATGGGGT
GGTTGCAACGGACAGGATTGGGCGAGTTATCATGATCAACGATATGGCCCAGAAGCAGTTGGGGTTATCGGGAAAAAAGC
AGGAACAGTACCATCTGCTAGAGGTGTTAGATTTACCAGATCGGTATACTCTCAGAGATTTGTTTGCTCAGACACCAGAG
ATTATTATTGAGCACACCAATGAAAATGAGGAATTTCTTACTCTTCGTGCCAATTTTGCTACCATTCGTAGCGAGAGCGG
CTTGATTTCAGGTCTAGTAGTCGTCTTGCACGATATGACCGAACAGGCCAAAGAAGAGCGAGAGCGGCGCTTATTCGTAT
CCAATGTCAGTCATGAATTGCGGACTCCTTTGACTTCTGTTAAGTCCTACTTAGAAGCCTTGGATGAAGGAGCTTTGACT
GAGTCGGTTGCCCCGAGTTTTGTCAAAGTATCCTTGGATGAAACCAATCGAATGATACGGATGATTACAGACTTGTTAAG
TCTCTCCCGAATCGACAATCAAGTTGGTCAGGTAGATGTGGAGCTGATCAATTTTACGGCTTTTGTAACCTTTATCCTCA
ACCGTTTTGACCAGATGAAAAATGCCGACTCTGATAAGGTTTACACCATTGTACGTGATTATCAGATTAGCCCAATTTGG
GTGGAGATTGATACTGATAAGATGACGCAAGTTTTAGATAATATCCTGAACAATGCTATCAAATACTCACCTGATGGTGG
TAGGATTACTTTTAGTATGAAAACGACAGACAGCCAGTTGATTGTGTCTATTTCCGATGAAGGCTTGGGGATTCCAAAGA
CAGACTTACCTAAAATTTTCGACCGTTTTTATCGGGTAGACAAGGCACGCTCAAGGGCACAAGGAGGCACTGGCTTAGGA
CTGGCCATTGCCAAAGAAATCATCAAGCAACACAGGGGCTTTATTTGGGCTAAGAGCGAGTATGGCCATGGTTCAACCTT
TACCATTGTCTTACCATATAGTAAGGACATTGCTCTTGACGATTGGGATGAAGCTTCTGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TLH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.037

97.105

0.67
  vicK Streptococcus mutans UA159

69.479

89.755

0.624

Multiple sequence alignment