Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   R3H37_RS00680 Genome accession   NZ_CP136948
Coordinates   105982..106416 (+) Length   144 a.a.
NCBI ID   WP_002992738.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Spyo01     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 100982..111416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R3H37_RS00650 (R3H37_00650) - 102651..103016 (+) 366 WP_002986560.1 DUF1033 family protein -
  R3H37_RS00655 (R3H37_00655) comYA 103109..104047 (+) 939 WP_023079010.1 competence type IV pilus ATPase ComGA Machinery gene
  R3H37_RS00660 (R3H37_00660) comYB 103983..105017 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  R3H37_RS00665 (R3H37_00665) comYC 105019..105345 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  R3H37_RS00670 (R3H37_00670) comGD 105320..105748 (+) 429 WP_129284411.1 competence type IV pilus minor pilin ComGD -
  R3H37_RS00675 (R3H37_00675) comGE 105705..105989 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  R3H37_RS00680 (R3H37_00680) comYF 105982..106416 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  R3H37_RS00685 (R3H37_00685) comGG 106400..106726 (+) 327 WP_009880358.1 competence type IV pilus minor pilin ComGG -
  R3H37_RS00690 (R3H37_00690) comYH 106824..107777 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  R3H37_RS00695 (R3H37_00695) - 107836..109032 (+) 1197 WP_002987791.1 acetate kinase -
  R3H37_RS00700 (R3H37_00700) - 109218..109526 (+) 309 WP_030126458.1 hypothetical protein -
  R3H37_RS00705 (R3H37_00705) proC 109609..110379 (-) 771 WP_063631714.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16645.27 Da        Isoelectric Point: 10.2526

>NTDB_id=893583 R3H37_RS00680 WP_002992738.1 105982..106416(+) (comYF) [Streptococcus pyogenes strain Spyo01]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide


Download         Length: 435 bp        

>NTDB_id=893583 R3H37_RS00680 WP_002992738.1 105982..106416(+) (comYF) [Streptococcus pyogenes strain Spyo01]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTTGTGATATCAGGATCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGATATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(41-135)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

51.079

96.528

0.493
  comYF Streptococcus mutans UA159

50.36

96.528

0.486
  comGF Lactococcus lactis subsp. cremoris KW2

46.715

95.139

0.444
  comGF/cglF Streptococcus mitis NCTC 12261

44.776

93.056

0.417
  comGF/cglF Streptococcus pneumoniae Rx1

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae D39

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae R6

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae TIGR4

43.609

92.361

0.403
  comGF/cglF Streptococcus mitis SK321

42.857

92.361

0.396