Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RL453_RS10980 Genome accession   NZ_CP134618
Coordinates   2265660..2266376 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain IPLA15     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2260660..2271376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL453_RS10960 (RL453_10945) - 2261752..2262702 (+) 951 WP_000790327.1 LacI family DNA-binding transcriptional regulator -
  RL453_RS10965 (RL453_10950) - 2262851..2264335 (+) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  RL453_RS10970 (RL453_10955) - 2264332..2265291 (+) 960 WP_001253302.1 carbohydrate kinase family protein -
  RL453_RS10975 (RL453_10960) - 2265479..2265588 (-) 110 Protein_2153 hypothetical protein -
  RL453_RS10980 (RL453_10965) agrA 2265660..2266376 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  RL453_RS10985 (RL453_10970) agrC 2266395..2267687 (-) 1293 WP_000387803.1 quorum-sensing sensor histidine kinase AgrC -
  RL453_RS10990 (RL453_10975) agrD 2267712..2267852 (-) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  RL453_RS10995 (RL453_10980) - 2267856..2268419 (-) 564 WP_001105705.1 accessory gene regulator AgrB -
  RL453_RS13980 hld 2268709..2268789 (+) 81 WP_000046023.1 delta-hemolysin -
  RL453_RS11005 (RL453_10990) - 2269388..2270173 (-) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  RL453_RS11010 (RL453_10995) - 2270534..2271160 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=882402 RL453_RS10980 WP_000688492.1 2265660..2266376(-) (agrA) [Staphylococcus aureus strain IPLA15]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=882402 RL453_RS10980 WP_000688492.1 2265660..2266376(-) (agrA) [Staphylococcus aureus strain IPLA15]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1